protein coding gene - sme1 (SPBC11G11.06c) - Sm snRNP core protein Sme1

Gene summary

Standard name

sme1

Systematic ID

SPBC11G11.06c

Product

Sm snRNP core protein Sme1

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

Q9USZ3

ORFeome ID

07/07C01

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome II: 1763466..1765196 reverse strand

Annotation

Protein features

Orthologs

• SNRPE (HGNC:11161) Homo sapiens
• sme1 (SJAG_03469) Schizosaccharomyces japonicus
• SME1 (YOR159C) Saccharomyces cerevisiae

References / Literature

PMID:24874881 - The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast.

Kallgren SP et al. PLoS Genet 2014;10(5):e1004334

PMID:25274039 - A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast.

Bayne EH et al. Genome Biol 2014;15(10):481

PMID:31219728 - Identification of proteins associated with splicing factors Ntr1, Ntr2, Brr2 and Gpl1 in the fission yeast Schizosaccharomyces pombe .

Cipakova I et al. Cell Cycle 2019 Jul;18(14):1532-1536

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs

PMID:26292707 - Structure of a yeast spliceosome at 3.6-angstrom resolution.

Yan C et al. Science 2015 Sep 11;349(6253):1182-91

PMID:24014766 - Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10.

Livesay SB et al. Eukaryot Cell 2013 Nov;12(11):1472-89

GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.

PMID:22446625 - Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexes.

Tang W et al. Nature 2012 Mar 25;484(7393):260-4

PMID:24442611 - Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes.

Chen W et al. RNA 2014 Mar;20(3):308-20

PMID:39833470 - Structures of aberrant spliceosome intermediates on their way to disassembly.

Soni K et al. Nat Struct Mol Biol 2025 Jan 20;

GO_REF:0000002 - Comments

PMID:30355493 - Expanded Interactome of the Intrinsically Disordered Protein Dss1.

Schenstrøm SM et al. Cell Rep 2018 Oct 23;25(4):862-870

PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.

Strachan J et al. J Cell Sci 2023 Dec 01;136(23)

PMID:24713849 - Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.

Egan ED et al. RNA 2014 Jun;20(6):867-81

PMID:17264129 - Proteomic analysis of the U1 snRNP of Schizosaccharomyces pombe reveals three essential organism-specific proteins.

Newo AN et al. Nucleic Acids Res 2007;35(5):1391-401

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:15755920 - Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.

Carnahan RH et al. Eukaryot Cell 2005 Mar;4(3):577-87

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:21386897 - Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.

Ren L et al. PLoS One 2011 Feb 28;6(2):e16719

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

GO_REF:0000033 - Annotation inferences using phylogenetic trees

PMID:28947618 - Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing.

Thakran P et al. EMBO J 2018 Jan 04;37(1):89-101

PMID:29422664 - Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast.

Páez-Moscoso DJ et al. Nat Commun 2018 Feb 08;9(1):587

PMID:24298023 - Characterization and in vivo functional analysis of the Schizosaccharomyces pombe ICLN gene.

Barbarossa A et al. Mol Cell Biol 2014 Feb;34(4):595-605