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protein coding gene - pfl5 (SPBC1289.15) - cell surface glycoprotein, flocculin Pfl5

Gene summary

Standard name
pfl5
Systematic ID
SPBC1289.15
Product
cell surface glycoprotein, flocculin Pfl5
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
SPBC8E4.07c
UniProt ID
Q9URU4
ORFeome ID
48/48F02
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome II: 4421395..4425608 forward strand

Annotation

Comment

PBO:0114316 - repeat containing

GO biological process

GO:0000128 - flocculation

References:

GO cellular component

GO:0005737 - cytoplasm

References:

GO:0070263 - external side of fungal-type cell wall

References:

GO molecular function

GO:0098632 - cell-cell adhesion mediator activity

References:

Miscellaneous functional group

PBO:0000068 - cell surface glycoprotein

Modification

MOD:00693 - glycosylated residue

References:

MOD:00006 - N-glycosylated residue

References:

MOD:00046 - O-phospho-L-serine

References:

Protein sequence feature

SO:0000418 - signal_peptide

References:

Qualitative gene expression

PomGeneEx:0000011 - RNA level increased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0000155 - increased flocculation

References:

Genotypes:

FYPO:0009038 - resistance to egtazic acid

References:

Genotypes:

FYPO:0000104 - sensitive to cycloheximide

References:

Genotypes:

FYPO:0000799 - sensitive to diamide

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0002177 - viable vegetative cell with normal cell morphology

References:

Genotypes:

Taxonomic conservation

PBO:0016885 - Schizosaccharomyces specific

Warnings

PBO:0036493 - 26 copies of a 35 amino acid repeat

Protein features

IDNameInterPro nameDB name
PF10182Flo11Flo11Pfam
PS51824FLO11Flo11PROSITE profiles
SM01213Flo11Flo11SMART
PTHR31492Mam3-likePANTHER
mobidb-lite-Disorderdisorder_predictionMobiDB-Disorder
mobidb-lite-Low-complexitydisorder_predictionMobiDB-Low-complexity
Signal PeptideSignal-Peptide-DeepTMHMM

Orthologs

References / Literature

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
GO_REF:0000050 - Manual transfer of GO annotation data to genes by curator judgment of sequence model
PMID:11452028 - Expression of hsp16 in response to nucleotide depletion is regulated via the spc1 MAPK pathway in Schizosaccharomyces pombe.
Taricani L et al. Nucleic Acids Res 2001 Jul 15;29(14):3030-40
PB_REF:0000001 - Protein modification annotation by manual transfer of experimentally-verified annotation data to orthologs based on curator judgment of sequence features.
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.
UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.
Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101
PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.
Mata J et al. Nat Genet 2002 Sep;32(1):143-7
PMID:26896847 - Ensembl comparative genomics resources.
Herrero J et al. Database (Oxford) 2016;2016
PMID:23236291 - Deciphering the transcriptional-regulatory network of flocculation in Schizosaccharomyces pombe.
Kwon EJ et al. PLoS Genet 2012;8(12):e1003104
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83