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protein coding gene - SPBC1348.09 - short chain dehydrogenase, implicated in cellular detoxification

Gene summary

Systematic ID
SPBC1348.09
Product
short chain dehydrogenase, implicated in cellular detoxification
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
SPAC1348.09
UniProt ID
P0CU01
Characterisation status
conserved unknown
Feature type
mRNA gene
Genomic location
chromosome II: 24916..25626 forward strand

Annotation

GO cellular component

GO:0005737 - cytoplasm

References:

GO:0005634 - nucleus

References:

GO molecular function

GO:0016491 - oxidoreductase activity

References:

Genome organisation

PBO:0000066 - telomeric duplication

Quantitative gene expression

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0002177 - viable vegetative cell with normal cell morphology

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0000055 - no apparent S. cerevisiae ortholog

Protein features

IDNameInterPro nameDB name
PF00106adh_shortSDR_famPFAM
PR00081GDHRDHSDR_famPRINTS
PR00080SDRFAMILYSDR_famPRINTS
SSF51735NAD(P)-binding Rossmann-fold domainsNAD(P)-bd_dom_sfSUPERFAMILY
G3DSA:3.40.50.720GENE3D
PTHR43976SHORT CHAIN DEHYDROGENASESDR_oxidoreductasePANTHER

References / Literature

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
GO_REF:0000050 - Manual transfer of GO annotation data to genes by curator judgment of sequence model
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.