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pseudogene - ght7 (SPBC1348.14c) - plasma membrane hexose transmembrane transporter Ght7

Gene summary

Standard name
ght7
Systematic ID
SPBC1348.14c
Product
plasma membrane hexose transmembrane transporter Ght7
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
SPBPB8B6.01c, SPAC1348.14c, SPAPB8B6.01c, SPAP8B6.01c
ORFeome ID
50/50H01
Feature type
pseudogene
Genomic location
chromosome II: 38514..40239 reverse strand

Annotation

GO biological process

GO:0034219 - carbohydrate transmembrane transport

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GO:1902600 - proton transmembrane transport

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GO cellular component

GO:0005737 - cytoplasm

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GO:0005886 - plasma membrane

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GO molecular function

GO:0005351 - carbohydrate:proton symporter activity

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Multi-locus phenotype

FYPO:0001355 - decreased vegetative cell population growth

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Genotypes:

FYPO:0000106 - sensitive to hygromycin B

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Genotypes:

Protein sequence feature

SO:0001812 - transmembrane_helix

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Qualitative gene expression

PomGeneEx:0000018 - protein level increased

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PomGeneEx:0000013 - RNA level unchanged

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Quantitative gene expression

PBO:0011963 - RNA level

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Single locus phenotype

FYPO:0001309 - increased viability in stationary phase

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Genotypes:

FYPO:0004765 - normal cell population growth during glucose starvation

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Genotypes:

FYPO:0010094 - normal growth on galactose/ethanol carbon source

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Genotypes:

FYPO:0001164 - normal growth on glucose carbon source

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Genotypes:

FYPO:0003898 - normal growth on glycerol/ethanol carbon source

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Genotypes:

FYPO:0001357 - normal vegetative cell population growth

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Genotypes:

FYPO:0002693 - resistance to diamide

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Genotypes:

FYPO:0000725 - resistance to methyl methanesulfonate

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Genotypes:

FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0007931 - sensitive to egtazic acid

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Genotypes:

FYPO:0001719 - sensitive to lithium

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Genotypes:

FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0002060 - viable vegetative cell population

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Genotypes:

FYPO:0002177 - viable vegetative cell with normal cell morphology

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Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

Orthologs

References / Literature

PMID:30730059 - Iron regulates hexose transporters in Schizosaccharomyces pombe.
Özkan E et al. J Basic Microbiol 2019 May;59(5):458-464
PMID:38899862 - Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.
Schwer B et al. mBio 2024 Jun 20;:e0125224
PMID:35781263 - Characterization of hexose transporter genes in the views of the chronological life span and glucose uptake in fission yeast.
Maruyama T et al. J Gen Appl Microbiol 2023 Mar 06;68(6):270-277
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:39833200 - Centromere positioning orchestrates telomere bouquet formation and the initiation of meiotic differentiation.
Jiménez-Martín A et al. Nat Commun 2025 Jan 20;16(1):837
PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.
Skribbe M et al. Mol Cell 2025 Feb 19;
PMID:42030144 - Gene loss, repression, amplification, and horizontal acquisition shape galactose/melibiose metabolism in fission yeast.
Du XM et al. Proc Natl Acad Sci U S A 2026 Apr 28;123(17):e2532532123
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:42015844 - Schizosaccharomyces Orthogroup (SOG) Resource: A Web Platform for Exploring Gene Conservation in Fission Yeasts.
Jia GS et al. Yeast 2026 Apr 22;
PMID:11152613 - Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
Krogh A et al. J Mol Biol 2001 Jan 19;305(3):567-80
PMID:40520116 - Histone deacetylation as a landmark for Sgo2 relocation from centromeres to subtelomeres during interphase.
Osaki M et al. iScience 2025 Jun 20;28(6):112717
PMID:26804021 - Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing.
Tashiro S et al. Nat Commun 2016 Jan 25;7:10393
GO_REF:0000108 - Automatic assignment of GO terms using logical inference, based on on inter-ontology links.
PMID:23050226 - A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.
Chen Z et al. G3 (Bethesda) 2012 Oct;2(10):1161-8
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:25411338 - Mechanisms of expression and translocation of major fission yeast glucose transporters regulated by CaMKK/phosphatases, nuclear shuttling, and TOR.
Saitoh S et al. Mol Biol Cell 2015 Jan 15;26(2):373-86
PMID:31626996 - Multiplexed proteome profiling of carbon source perturbations in two yeast species with SL-SP3-TMT.
Paulo JA et al. J Proteomics 2020 Jan 06;210:103531
PMID:23254763 - Ght2⁺ is required for UDP-galactose synthesis from extracellular galactose by Schizosaccharomyces pombe.
Matsuzawa T et al. Appl Microbiol Biotechnol 2013 Jun;97(11):4957-64
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83