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protein coding gene - myo1 (SPBC146.13c) - myosin type I

Gene summary

Standard name
myo1
Systematic ID
SPBC146.13c
Product
myosin type I
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
Q9Y7Z8
ORFeome ID
39/39C03
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome II: 1023963..1027973 reverse strand

Annotation

Disease association

MONDO:0013589 - focal segmental glomerulosclerosis 6

References:

GO biological process

GO:0030036 - actin cytoskeleton organization

References:

GO:0072583 - clathrin-dependent endocytosis

References:

GO:0030989 - dynein-driven meiotic oscillatory nuclear movement

References:

GO:0000281 - mitotic cytokinesis

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GO cellular component

GO:0030479 - actin cortical patch

References:

GO:0051285 - cell cortex of cell tip

References:

GO:0032153 - cell division site

References:

GO:0051286 - cell tip

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GO:0005737 - cytoplasm

References:

GO:0061645 - endocytic patch

References:

GO:0043332 - mating projection tip

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GO:0031097 - medial cortex

References:

GO:0045160 - myosin I complex

References:

GO:0005886 - plasma membrane

References:

GO:0005628 - prospore membrane

References:

GO molecular function

GO:0051015 - actin filament binding

References:

GO:0071933 - Arp2/3 complex binding

References:

GO:0005524 - ATP binding

References:

GO:0016887 - ATP hydrolysis activity

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GO:0008289 - lipid binding

References:

GO:0000146 - microfilament motor activity

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

MOD:00047 - O-phospho-L-threonine

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MOD:00048 - O4'-phospho-L-tyrosine

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MOD:00696 - phosphorylated residue

References:

MOD:01148 - ubiquitinylated lysine

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Multi-locus phenotype

FYPO:0002196 - abnormal vegetative cell shape

References:

Genotypes:

FYPO:0004481 - abolished cell population growth at high temperature

References:

Genotypes:

FYPO:0006796 - abolished protein localization to actin cortical patch, with protein mislocalized to cytoplasm

References:

Genotypes:

FYPO:0006795 - abolished protein localization to actin cortical patch, with protein mislocalized to nucleus

References:

Genotypes:

FYPO:0000422 - decreased endocytosis during vegetative growth

References:

Genotypes:

FYPO:0000708 - decreased mating efficiency

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

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Genotypes:

FYPO:0003482 - increased punctate cytoplasmic protein localization

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Genotypes:

FYPO:0002150 - inviable spore population

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Genotypes:

FYPO:0002061 - inviable vegetative cell population

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Genotypes:

FYPO:0003210 - mislocalized, misoriented septum

References:

Genotypes:

FYPO:0001147 - normal mating efficiency

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Genotypes:

FYPO:0001357 - normal vegetative cell population growth

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Genotypes:

FYPO:0002526 - sensitive to latrunculin B

References:

Genotypes:

FYPO:0000021 - spheroid vegetative cell

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Genotypes:

FYPO:0002060 - viable vegetative cell population

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Genotypes:

Protein features

PBO:0111829 - IQ domain

Qualitative gene expression

PomGeneEx:0000023 - protein level constant

References:

PomGeneEx:0000011 - RNA level increased

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Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

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Single locus phenotype

FYPO:0000728 - abnormal actin cortical patch assembly

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Genotypes:

FYPO:0000743 - abnormal actin cortical patch internalization

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Genotypes:

FYPO:0005666 - abnormal actin cytoskeleton during meiosis

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Genotypes:

FYPO:0002946 - abnormal cell wall

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Genotypes:

FYPO:0007285 - abnormal dynamic protein localization to cell tip

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Genotypes:

FYPO:0006121 - abnormal membrane raft distribution

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Genotypes:

FYPO:0006497 - abnormal plasma membrane phosphatidylserine distribution

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Genotypes:

FYPO:0000135 - abnormal plasma membrane sterol distribution

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Genotypes:

FYPO:0000196 - abnormal prospore formation

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Genotypes:

FYPO:0000191 - abnormal regulation of establishment or maintenance of cell polarity

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Genotypes:

FYPO:0002023 - abnormal septum morphology during vegetative growth

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Genotypes:

FYPO:0001894 - abnormal sporulation resulting in formation of ascus with more or fewer than four spores

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Genotypes:

FYPO:0000428 - abolished entry into G0

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Genotypes:

FYPO:0000927 - abolished horsetail movement

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Genotypes:

FYPO:0003209 - abolished protein localization to cell tip, with protein mislocalized to cytoplasm

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Genotypes:

FYPO:0000705 - abolished protein-protein interaction

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Genotypes:

FYPO:0000583 - abolished sporulation

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Genotypes:

FYPO:0006030 - actin cortical patches absent from cell

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Genotypes:

FYPO:0004972 - actin cortical patches present in increased numbers

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Genotypes:

FYPO:0000082 - decreased cell population growth at high temperature

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Genotypes:

FYPO:0009078 - decreased cell population growth on ethanol carbon source

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Genotypes:

FYPO:0009053 - decreased cell population growth on glutamate nitrogen source

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Genotypes:

FYPO:0009100 - decreased cell population growth on glycerol and galactose carbon source

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Genotypes:

FYPO:0000684 - decreased cell population growth on glycerol carbon source

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Genotypes:

FYPO:0002924 - decreased cell population growth on maltose carbon source

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Genotypes:

FYPO:0001176 - decreased cell population growth on sucrose carbon source

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Genotypes:

FYPO:0004446 - decreased endocytosis during meiotic cell cycle

References:

Genotypes:

FYPO:0000422 - decreased endocytosis during vegetative growth

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Genotypes:

FYPO:0004971 - decreased level of stress responsive gene mRNA during cellular response to phosphate starvation

References:

Genotypes:

FYPO:0000708 - decreased mating efficiency

References:

Genotypes:

FYPO:0006120 - decreased protein localization to actin cortical patch

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Genotypes:

FYPO:0006868 - decreased protein localization to cell cortex during meiotic prophase I

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Genotypes:

FYPO:0001586 - decreased protein localization to cell tip during vegetative growth

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Genotypes:

FYPO:0003208 - decreased protein localization to cell tip, with protein distributed in plasma membrane or cortex

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Genotypes:

FYPO:0004444 - decreased protein localization to prospore membrane during meiosis II with protein mislocalized to plasma membrane

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Genotypes:

FYPO:0001365 - decreased rate of actomyosin contractile ring contraction

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Genotypes:

FYPO:0003014 - decreased rate of actomyosin contractile ring disassembly

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Genotypes:

FYPO:0001117 - decreased RNA level during vegetative growth

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Genotypes:

FYPO:0000584 - decreased sporulation frequency

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Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

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Genotypes:

FYPO:0004653 - delayed onset of actomyosin contractile ring contraction

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Genotypes:

FYPO:0006797 - delayed onset of cell separation after cytokinesis

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Genotypes:

FYPO:0000639 - delayed onset of septum assembly

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Genotypes:

FYPO:0002021 - dispersed actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0001253 - elongated multinucleate multiseptate vegetative cell, single septa between nuclei

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Genotypes:

FYPO:0004167 - increased cell population growth on glycerol carbon source

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Genotypes:

FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

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Genotypes:

FYPO:0009072 - increased cell population growth on lysine nitrogen source

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Genotypes:

FYPO:0001974 - increased number of cells with 1C DNA content

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Genotypes:

FYPO:0000650 - increased septation index

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Genotypes:

FYPO:0001406 - increased septum thickness

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Genotypes:

FYPO:0004557 - increased vegetative cell population growth

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Genotypes:

FYPO:0004967 - increased vegetative cell population growth during phosphate starvation

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Genotypes:

FYPO:0001309 - increased viability in stationary phase

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Genotypes:

FYPO:0006794 - inviable branched, swollen vegetative cell

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Genotypes:

FYPO:0002061 - inviable vegetative cell population

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Genotypes:

FYPO:0000245 - loss of viability in stationary phase

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Genotypes:

FYPO:0003452 - mislocalized protein

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Genotypes:

FYPO:0003210 - mislocalized, misoriented septum

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Genotypes:

FYPO:0002487 - normal actin cable morphology

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Genotypes:

FYPO:0001294 - normal actin cortical patch localization

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Genotypes:

FYPO:0002022 - normal actin cortical patch morphology

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Genotypes:

FYPO:0001368 - normal actomyosin contractile ring assembly

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Genotypes:

FYPO:0000980 - normal growth on amphotericin B

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Genotypes:

FYPO:0000961 - normal growth on sorbitol

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Genotypes:

FYPO:0003835 - normal horsetail movement

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Genotypes:

FYPO:0003627 - normal protein localization

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Genotypes:

FYPO:0000744 - normal protein localization to actin cortical patch

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Genotypes:

FYPO:0002442 - normal protein localization to cell division site

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Genotypes:

FYPO:0001587 - normal protein localization to cell tip during vegetative growth

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Genotypes:

FYPO:0002674 - normal protein localization to plasma membrane

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Genotypes:

FYPO:0008003 - normal protein localization to site of mechanical stress

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Genotypes:

FYPO:0007671 - normal transcription scaling

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Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0004969 - normal vegetative cell population growth during phosphate starvation

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Genotypes:

FYPO:0006119 - protein mislocalized to actin cable

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Genotypes:

FYPO:0004730 - protein mislocalized to lateral cell cortex

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Genotypes:

FYPO:0000067 - resistance to brefeldin A

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Genotypes:

FYPO:0009038 - resistance to egtazic acid

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Genotypes:

FYPO:0001453 - resistance to ethanol

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Genotypes:

FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0001034 - resistance to tunicamycin

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Genotypes:

FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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Genotypes:

FYPO:0009067 - sensitive to amorolfine

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Genotypes:

FYPO:0007921 - sensitive to benzamidine

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Genotypes:

FYPO:0000095 - sensitive to bleomycin

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Genotypes:

FYPO:0001701 - sensitive to bortezomib

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Genotypes:

FYPO:0000096 - sensitive to cadmium

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Genotypes:

FYPO:0000097 - sensitive to caffeine during vegetative growth

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Genotypes:

FYPO:0009080 - sensitive to calcofluor and sodium dodecyl sulfate

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Genotypes:

FYPO:0000104 - sensitive to cycloheximide

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Genotypes:

FYPO:0000799 - sensitive to diamide

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Genotypes:

FYPO:0000842 - sensitive to ethanol during vegetative growth

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Genotypes:

FYPO:0007928 - sensitive to ethylenediaminetetraacetic acid

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Genotypes:

FYPO:0000785 - sensitive to formamide

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Genotypes:

FYPO:0000087 - sensitive to hydrogen peroxide

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Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

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Genotypes:

FYPO:0009071 - sensitive to itraconazole

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Genotypes:

FYPO:0000107 - sensitive to latrunculin A

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Genotypes:

FYPO:0001719 - sensitive to lithium

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Genotypes:

FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

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Genotypes:

FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0000089 - sensitive to methyl methanesulfonate

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Genotypes:

FYPO:0002641 - sensitive to micafungin

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Genotypes:

FYPO:0001214 - sensitive to potassium chloride

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Genotypes:

FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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Genotypes:

FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0000271 - sensitive to salt stress

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Genotypes:

FYPO:0005889 - sensitive to sodium chloride

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Genotypes:

FYPO:0009090 - sensitive to sodium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0000841 - sensitive to sodium dodecyl sulfate

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Genotypes:

FYPO:0000086 - sensitive to tacrolimus

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Genotypes:

FYPO:0002328 - sensitive to terbinafine

References:

Genotypes:

FYPO:0000797 - sensitive to tert-butyl hydroperoxide

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Genotypes:

FYPO:0000091 - sensitive to thiabendazole

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Genotypes:

FYPO:0002701 - sensitive to torin1

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Genotypes:

FYPO:0000268 - sensitive to UV during vegetative growth

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Genotypes:

FYPO:0000115 - sensitive to valproic acid

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Genotypes:

FYPO:0003656 - sensitive to vanadate

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Genotypes:

FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

References:

Genotypes:

FYPO:0001234 - slow vegetative cell population growth

References:

Genotypes:

FYPO:0000021 - spheroid vegetative cell

References:

Genotypes:

FYPO:0000647 - vegetative cell lysis

References:

Genotypes:

FYPO:0004970 - viable elongated vegetative cell during phosphate starvation

References:

Genotypes:

FYPO:0002106 - viable stubby vegetative cell

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0002197 - viable vegetative cell with abnormal cell shape

References:

Genotypes:

FYPO:0002176 - viable vegetative cell with normal cell size

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

Protein features

IDNameInterPro nameDB name
PF00018SH3_1SH3_domainPfam
PF00063Myosin_headMyosin_head_motor_dom-likePfam
PF06017Myosin_TH1Myosin_TH1Pfam
PF22773Myo1_CAMyo1_CAPfam
cd01378MYSc_Myo1MYSc_Myo1CDD
cd11858SH3_Myosin-I_fungiFungal_myosin-I_SH3CDD
PS50002SH3SH3_domainPROSITE profiles
PS51456MYOSIN_MOTORMyosin_head_motor_dom-likePROSITE profiles
PS51757TH1Myosin_TH1PROSITE profiles
SM00242MYScMyosin_head_motor_dom-likeSMART
SM00326SH3SH3_domainSMART
PR00193MYOSINHEAVYMyosin_head_motor_dom-likePRINTS
G3DSA:1.10.10.820:FF:000001CATH-FunFam
G3DSA:1.20.120.720:FF:000015CATH-FunFam
G3DSA:1.20.5.4820:FF:000004CATH-FunFam
G3DSA:1.20.58.530:FF:000007CATH-FunFam
G3DSA:1.10.10.820CATH-Gene3D
G3DSA:1.20.120.720CATH-Gene3D
G3DSA:1.20.5.4820CATH-Gene3D
G3DSA:1.20.58.530CATH-Gene3D
G3DSA:2.30.30.40CATH-Gene3D
G3DSA:3.40.850.10Kinesin_motor_dom_sfCATH-Gene3D
SSF50044SH3-like_dom_sfSUPERFAMILY
SSF52540P-loop_NTPaseSUPERFAMILY
PTHR13140PANTHER
mobidb-lite-Disorderdisorder_predictionMobiDB-Disorder
mobidb-lite-Low-complexitydisorder_predictionMobiDB-Low-complexity
mobidb-lite-Polardisorder_predictionMobiDB-Polar
mobidb-lite-Proline-richdisorder_predictionMobiDB-Proline-rich

Orthologs

References / Literature

PMID:21850271 - Genome-wide screening for genes associated with FK506 sensitivity in fission yeast.
Ma Y et al. PLoS One 2011;6(8):e23422
PMID:20603077 - Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site.
Roberts-Galbraith RH et al. Mol Cell 2010 Jul 09;39(1):86-99
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:33330476 - Comparative Analysis of the Roles of Non-muscle Myosin-IIs in Cytokinesis in Budding Yeast, Fission Yeast, and Mammalian Cells.
Wang K et al. Front Cell Dev Biol 2020;8:593400
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:27918601 - Identifying genes required for respiratory growth of fission yeast.
Malecki M et al. Wellcome Open Res 2016;1:12
PMID:30201262 - Fission yeast Adf1 is necessary for reassembly of actin filaments into the contractile ring during cytokinesis.
Ueda EI et al. Biochem Biophys Res Commun 2018 Nov 25;506(2):330-338
PMID:31391237 - The S. pombe adaptor protein Bbc1 regulates localization of Wsp1 and Vrp1 during endocytic actin patch assembly.
MacQuarrie CD et al. J Cell Sci 2019 Sep 11;132(17)
PMID:16864655 - Assembly of the cytokinetic contractile ring from a broad band of nodes in fission yeast.
Wu JQ et al. J Cell Biol 2006 Jul 31;174(3):391-402
PMID:23950735 - Global analysis of fission yeast mating genes reveals new autophagy factors.
Sun LL et al. PLoS Genet 2013;9(8):e1003715
PMID:11260263 - Identification and functional analysis of the gene for type I myosin in fission yeast.
Toya M et al. Genes Cells 2001 Mar;6(3):187-99
PMID:19098712 - Rng3, a member of the UCS family of myosin co-chaperones, associates with myosin heavy chains cotranslationally.
Amorim MJ et al. EMBO Rep 2009 Feb;10(2):186-91
PMID:16087707 - Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast.
Sirotkin V et al. J Cell Biol 2005 Aug 15;170(4):637-48
PMID:21832151 - Endocytosis is essential for dynamic translocation of a syntaxin 1 orthologue during fission yeast meiosis.
Kashiwazaki J et al. Mol Biol Cell 2011 Oct;22(19):3658-70
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.
Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
PMID:27180904 - Sterol-Rich Membrane Domains Define Fission Yeast Cell Polarity.
Makushok T et al. Cell 2016 May 19;165(5):1182-1196
PMID:20838651 - A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity.
Kouranti I et al. PLoS Biol 2010 Sep 07;8(9)
PMID:23738021 - A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe.
Zhou X et al. PLoS One 2013;8(5):e65904
PMID:11112691 - Two type V myosins with non-overlapping functions in the fission yeast Schizosaccharomyces pombe: Myo52 is concerned with growth polarity and cytokinesis, Myo51 is a component of the cytokinetic actin ring.
Win TZ et al. J Cell Sci 2001 Jan;114(Pt 1):69-79
PMID:17202724 - Localization of type I myosin and F-actin to the leading edge region of the forespore membrane in Schizosaccharomyces pombe.
Itadani A et al. Cell Struct Funct 2006;31(2):181-95
PMID:20519959 - S. pombe genome deletion project: an update.
Spirek M et al. Cell Cycle 2010 Jun 15;9(12):2399-402
PMID:21620704 - Characterization of dip1p reveals a switch in Arp2/3-dependent actin assembly for fission yeast endocytosis.
Basu R et al. Curr Biol 2011 Jun 07;21(11):905-16
PMID:31217286 - Increasing ergosterol levels delays formin-dependent assembly of F-actin cables and disrupts division plane positioning in fission yeast.
Arbizzani F et al. J Cell Sci 2019 Jul 01;132(13)
PMID:21885283 - Distinct roles for F-BAR proteins Cdc15p and Bzz1p in actin polymerization at sites of endocytosis in fission yeast.
Arasada R et al. Curr Biol 2011 Sep 13;21(17):1450-9
PMID:39476757 - Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.
Cipak L et al. Biochem Biophys Res Commun 2024 Oct 25;736:150895
GO_REF:0000117 - Electronic Gene Ontology annotations created by ARBA machine learning models
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:20705471 - Differential regulation of unconventional fission yeast myosins via the actin track.
Clayton JE et al. Curr Biol 2010 Aug 24;20(16):1423-31
PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.
Halova L et al. Open Biol 2021 Apr;11(4):200405
PMID:12939254 - The PCH family protein, Cdc15p, recruits two F-actin nucleation pathways to coordinate cytokinetic actin ring formation in Schizosaccharomyces pombe.
Carnahan RH et al. J Cell Biol 2003 Sep 01;162(5):851-62
PMID:28784611 - Phosphoinositide-mediated ring anchoring resists perpendicular forces to promote medial cytokinesis.
Snider CE et al. J Cell Biol 2017 Oct 02;216(10):3041-3050
PMID:16537923 - Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.
Todd BL et al. Mol Cell Biol 2006 Apr;26(7):2817-31
PMID:32059768 - Size-Dependent Increase in RNA Polymerase II Initiation Rates Mediates Gene Expression Scaling with Cell Size.
Sun XM et al. Curr Biol 2020 Apr 06;30(7):1217-1230.e7
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:29996109 - Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.
Swaffer MP et al. Cell Rep 2018 Jul 10;24(2):503-514
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:19547744 - Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.
Beltrao P et al. PLoS Biol 2009 Jun 16;7(6):e1000134
PMID:19672306 - Genome-wide screen of genes required for caffeine tolerance in fission yeast.
Calvo IA et al. PLoS One 2009 Aug 12;4(8):e6619
PMID:18257517 - Phosphoproteome analysis of fission yeast.
Wilson-Grady JT et al. J Proteome Res 2008 Mar;7(3):1088-97
PMID:20587778 - Quantitative analysis of the mechanism of endocytic actin patch assembly and disassembly in fission yeast.
Sirotkin V et al. Mol Biol Cell 2010 Aug 15;21(16):2894-904
PMID:15504913 - UCS protein Rng3p activates actin filament gliding by fission yeast myosin-II.
Lord M et al. J Cell Biol 2004 Oct 25;167(2):315-25
PMID:21693583 - A calmodulin-related light chain from fission yeast that functions with myosin-I and PI 4-kinase.
Sammons MR et al. J Cell Sci 2011 Jul 15;124(Pt 14):2466-77
PMID:27053105 - Mga2 Transcription Factor Regulates an Oxygen-responsive Lipid Homeostasis Pathway in Fission Yeast.
Burr R et al. J Biol Chem 2016 Jun 03;291(23):12171-83
PMID:37531259 - Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins.
Willet AH et al. Mol Biol Cell 2023 Oct 01;34(11):br17
PMID:39110593 - VAP-mediated membrane-tethering mechanisms implicate ER-PM contact function in pH homeostasis.
Hoh KL et al. Cell Rep 2024 Aug 05;43(8):114592
PMID:19808887 - Ste20-kinase-dependent TEDS-site phosphorylation modulates the dynamic localisation and endocytic function of the fission yeast class I myosin, Myo1.
Attanapola SL et al. J Cell Sci 2009 Nov 01;122(Pt 21):3856-61
PMID:19805578 - Genome-wide mapping of myosin protein-RNA networks suggests the existence of specialized protein production sites.
Mata J FASEB J 2010 Feb;24(2):479-84
PMID:19264558 - Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.
Deshpande GP et al. DNA Repair (Amst) 2009 May 01;8(5):672-9
PMID:26412298 - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.
Beckley JR et al. Mol Cell Proteomics 2015 Dec;14(12):3132-41
PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.
Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
PMID:18346214 - btn1 affects endocytosis, polarization of sterol-rich membrane domains and polarized growth in Schizosaccharomyces pombe.
Codlin S et al. Traffic 2008 Jun;9(6):936-50
PMID:18684775 - A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.
Kennedy PJ et al. Toxicol Sci 2008 Nov;106(1):124-39
PMID:25422470 - Oscillatory AAA+ ATPase Knk1 constitutes a novel morphogenetic pathway in fission yeast.
Scheffler K et al. Proc Natl Acad Sci U S A 2014 Dec 16;111(50):17899-904
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:23297348 - Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.
Chen JS et al. Mol Cell Proteomics 2013 May;12(5):1074-86
PMID:40205688 - Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms.
Brooker HR et al. Cytoskeleton (Hoboken) 2025 Apr 09;
GO_REF:0000002 - Comments
PMID:16866873 - Actin-capping protein is involved in controlling organization of actin cytoskeleton together with ADF/cofilin, profilin and F-actin crosslinking proteins in fission yeast.
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