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protein coding gene - rli1 (SPBC14F5.06) - iron-sulfur ATPase involved in ribosome biogenesis and translation Rli1

Gene summary

Standard name
rli1
Systematic ID
SPBC14F5.06
Product
iron-sulfur ATPase involved in ribosome biogenesis and translation Rli1
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
O60102
ORFeome ID
46/46F12
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome II: 4164628..4167261 forward strand

Annotation

GO biological process

GO:0002183 - cytoplasmic translational initiation

References:

GO:0042273 - ribosomal large subunit biogenesis

References:

GO:0006415 - translational termination

References:

GO cellular component

GO:0005829 - cytosol

References:

GO:0005634 - nucleus

References:

GO molecular function

GO:0005524 - ATP binding

References:

GO:0016887 - ATP hydrolysis activity

References:

GO:0005506 - iron ion binding

References:

GO:0051536 - iron-sulfur cluster binding

References:

GO:0043024 - ribosomal small subunit binding

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

MOD:01148 - ubiquitinylated lysine

References:

Qualitative gene expression

PomGeneEx:0000019 - protein level decreased

References:

PomGeneEx:0000012 - RNA level decreased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002151 - inviable spore

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011072 - conserved in archaea

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF00005ABC_tranABC_transporter-like_ATP-bdPfam
PF00037Fer44Fe4S_Fe-S-bdPfam
PF04068Fer4_RLIRNaseL-inhib-like_metal-bd_domPfam
cd03236ABC_RNaseL_inhibitor_domain1RLI_dom_1CDD
PS001984FE4S_FER_14Fe4S_Fe_S_CSPROSITE patterns
PS00211ABC_TRANSPORTER_1ABC_transporter-like_CSPROSITE patterns
PS50893ABC_TRANSPORTER_2ABC_transporter-like_ATP-bdPROSITE profiles
PS513794FE4S_FER_24Fe4S_Fe-S-bdPROSITE profiles
SM00382AAAAAA+_ATPaseSMART
PR01868ABCEFAMILYRLI1PRINTS
G3DSA:3.40.50.300:FF:000144CATH-FunFam
G3DSA:3.40.50.300:FF:000152CATH-FunFam
G3DSA:3.40.50.300P-loop_NTPaseCATH-Gene3D
SSF52540P-loop_NTPaseSUPERFAMILY
SSF54862SUPERFAMILY
PTHR19248RLI1PANTHER
NF009945PRK13409.1NCBIFAM

Orthologs

References / Literature

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:12529438 - Global transcriptional responses of fission yeast to environmental stress.
Chen D et al. Mol Biol Cell 2003 Jan;14(1):214-29
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:26412298 - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.
Beckley JR et al. Mol Cell Proteomics 2015 Dec;14(12):3132-41
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
GO_REF:0000002 - Comments
PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.
Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:28218250 - Chromatin remodeller Fun30 Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.
Lee J et al. Nat Commun 2017 Feb 20;8:14527
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:26167880 - SR protein kinases promote splicing of nonconsensus introns.
Lipp JJ et al. Nat Struct Mol Biol 2015 Aug;22(8):611-7
PMID:38051102 - Fission Yeast TORC1 Promotes Cell Proliferation through Sfp1, a Transcription Factor Involved in Ribosome Biogenesis.
Tai YT et al. Mol Cell Biol 2023 Dec 05;:1-18
GO_REF:0000050 - Manual transfer of GO annotation data to genes by curator judgment of sequence model
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:18257517 - Phosphoproteome analysis of fission yeast.
Wilson-Grady JT et al. J Proteome Res 2008 Mar;7(3):1088-97
PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.
Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.
Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623