PomBase home

protein coding gene - mam3302 (SPBC15D4.11c) - mitochondrial Mam33 family protein, Mam3302

Gene summary

Standard name
mam3302
Systematic ID
SPBC15D4.11c
Product
mitochondrial Mam33 family protein, Mam3302
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
O74316
ORFeome ID
13/13H01
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome II: 3030371..3031460 reverse strand

Annotation

Disease association

MONDO:0054677 - combined oxidative phosphorylation deficiency 33

References:

GO biological process

GO:1902775 - mitochondrial large ribosomal subunit assembly

References:

GO:0000957 - mitochondrial RNA catabolic process

References:

GO cellular component

GO:0005759 - mitochondrial matrix

References:

GO:0005739 - mitochondrion

References:

GO molecular function

GO:0062153 - C5-methylcytidine-containing RNA reader activity

References:

Modification

MOD:00693 - glycosylated residue

References:

Qualitative gene expression

PomGeneEx:0000018 - protein level increased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0000478 - normal meiosis

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

Protein features

IDNameInterPro nameDB name
PF02330MAM33MAM33PFAM
SSF54529Mitochondrial glycoprotein MAM33-likeMAM33_sfSUPERFAMILY
G3DSA:3.10.280.10Mitochondrial glycoproteinMAM33_sfGENE3D
PTHR10826COMPLEMENT COMPONENT 1MAM33PANTHER

Orthologs

References / Literature

PMID:16169489 - Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.
Gregan J et al. Curr Biol 2005 Sep 20;15(18):1663-9
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
Pfam:PF02330 - Unknown title
PMID:31626996 - Multiplexed proteome profiling of carbon source perturbations in two yeast species with SL-SP3-TMT.
Paulo JA et al. J Proteomics 2020 Jan 06;210:103531
PMID:28821619 - Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast.
Burr R et al. J Biol Chem 2017 Sep 29;292(39):16333-16350
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6