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protein coding gene - rsm25 (SPBC16A3.04) - mitochondrial ribosomal protein subunit S23

Gene summary

Standard name
rsm25
Systematic ID
SPBC16A3.04
Product
mitochondrial ribosomal protein subunit S23
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
O42911
ORFeome ID
07/07F08
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome II: 4290896..4291962 reverse strand

Annotation

Disease association

MONDO:0033534 - combined oxidative phosphorylation deficiency 46

References:

GO biological process

GO:0032543 - mitochondrial translation

References:

GO cellular component

GO:0005763 - mitochondrial small ribosomal subunit

References:

GO:0005739 - mitochondrion

References:

GO molecular function

GO:0003735 - structural constituent of ribosome

References:

Modification

MOD:01148 - ubiquitinylated lysine

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF13741MRP-S25Ribosomal_mS23_funPFAM
cd23701At1g26750mS23_domCDD
PTHR3779937S RIBOSOMAL PROTEIN S25, MITOCHONDRIALRibosomal_mS23_funPANTHER
PIRSF029764RSM25Ribosomal_mS23_funPIRSF

Orthologs

References / Literature

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.
Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
PANTHER:PTHR15925 - Unknown title
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7