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protein coding gene - mrpl23 (SPBC16G5.04) - mitochondrial ribosomal protein subunit L13

Gene summary

Standard name
mrpl23
Systematic ID
SPBC16G5.04
Product
mitochondrial ribosomal protein subunit L13
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
O60118
ORFeome ID
05/05A12
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome II: 4219773..4220616 forward strand

Annotation

GO biological process

GO:0032543 - mitochondrial translation

References:

GO cellular component

GO:0005762 - mitochondrial large ribosomal subunit

References:

GO:0005739 - mitochondrion

References:

GO molecular function

GO:0003729 - mRNA binding

References:

GO:0003735 - structural constituent of ribosome

References:

Protein sequence feature

SO:0001808 - mitochondrial_targeting_signal

References:

Qualitative gene expression

PomGeneEx:0000012 - RNA level decreased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0002199 - inviable vegetative cell with normal cell morphology

References:

Genotypes:

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF00572Ribosomal_L13Ribosomal_uL13Pfam
cd00392Ribosomal_L13Ribosomal_uL13CDD
G3DSA:3.90.1180.10:FF:000007CATH-FunFam
G3DSA:3.90.1180.10Ribosomal_uL13_sfCATH-Gene3D
SSF52161Ribosomal_uL13_sfSUPERFAMILY
PTHR11545Ribosomal_uL13PANTHER
PIRSF002181Ribosomal_L13Ribosomal_uL13_bactPIRSF
TIGR01066rplM_bactRibosomal_uL13_bactNCBIFAM
MF_01366Ribosomal_uL13Ribosomal_uL13HAMAP

Orthologs

References / Literature

GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:16537923 - Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.
Todd BL et al. Mol Cell Biol 2006 Apr;26(7):2817-31
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.
UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:30321377 - Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome.
Telekawa C et al. Nucleic Acids Res 2018 Nov 30;46(21):11169-11183
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.