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protein coding gene - tea4 (SPBC1706.01) - tip elongation aberrant protein Tea4

Gene summary

Standard name
tea4
Systematic ID
SPBC1706.01
Product
tip elongation aberrant protein Tea4
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
wsh3
UniProt ID
O60132
ORFeome ID
28/28G01
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome II: 588359..591434 forward strand

Annotation

GO biological process

GO:0061171 - establishment of bipolar cell polarity

References:

GO:0030010 - establishment of cell polarity

References:

GO:0030950 - establishment or maintenance of actin cytoskeleton polarity

References:

GO:0061245 - establishment or maintenance of bipolar cell polarity

References:

GO cellular component

GO:0051285 - cell cortex of cell tip

References:

GO:0032153 - cell division site

References:

GO:0051286 - cell tip

References:

GO:0097575 - lateral cell cortex

References:

GO:0035371 - microtubule plus-end

References:

GO:0035839 - non-growing cell tip

References:

GO:0035840 - old growing cell tip

References:

GO molecular function

GO:0008093 - cytoskeletal adaptor activity

References:

GO:0005515 - protein binding

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

MOD:00047 - O-phospho-L-threonine

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MOD:00048 - O4'-phospho-L-tyrosine

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MOD:00696 - phosphorylated residue

References:

MOD:01148 - ubiquitinylated lysine

References:

Multi-locus phenotype

FYPO:0000161 - abnormal actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0003013 - abnormal actomyosin contractile ring disassembly

References:

Genotypes:

FYPO:0000117 - abnormal septum assembly

References:

Genotypes:

FYPO:0000026 - abnormal vegetative cell polarity

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Genotypes:

FYPO:0001018 - abolished NETO

References:

Genotypes:

FYPO:0000930 - abolished protein localization to cell cortex during vegetative growth

References:

Genotypes:

FYPO:0002126 - abolished protein localization to plasma membrane during vegetative growth

References:

Genotypes:

FYPO:0002128 - abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth

References:

Genotypes:

FYPO:0003315 - actin cables absent from cell

References:

Genotypes:

FYPO:0006027 - actin cables present in increased numbers

References:

Genotypes:

FYPO:0006030 - actin cortical patches absent from cell

References:

Genotypes:

FYPO:0000016 - curved vegetative cell

References:

Genotypes:

FYPO:0000082 - decreased cell population growth at high temperature

References:

Genotypes:

FYPO:0001407 - decreased cell population growth on glucose carbon source

References:

Genotypes:

FYPO:0003150 - decreased NETO

References:

Genotypes:

FYPO:0006637 - decreased protein localization to cell cortex of cell tip, with protein distributed in cortex

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0002482 - inviable spheroid vegetative cell

References:

Genotypes:

FYPO:0001294 - normal actin cortical patch localization

References:

Genotypes:

FYPO:0005465 - normal cell polarity

References:

Genotypes:

FYPO:0007451 - normal protein localization to cell cortex of cell tip during vegetative growth

References:

Genotypes:

FYPO:0001315 - normal vegetative cell morphology

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0003302 - nucleus mislocalized towards cell tip during mitotic interphase

References:

Genotypes:

FYPO:0001120 - pear-shaped vegetative cell

References:

Genotypes:

FYPO:0001017 - premature NETO

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Genotypes:

FYPO:0000021 - spheroid vegetative cell

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Genotypes:

FYPO:0002942 - swollen spheroid cell during G0

References:

Genotypes:

FYPO:0000945 - swollen spheroid vegetative cell

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Genotypes:

FYPO:0000013 - T-shaped vegetative cell with normal cell length

References:

Genotypes:

FYPO:0002112 - viable curved vegetative cell

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Genotypes:

FYPO:0003389 - viable elongated vegetative cell with swollen medial region

References:

Genotypes:

FYPO:0004103 - viable spherical vegetative cell

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Genotypes:

FYPO:0007231 - viable spindle-shaped cell

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Genotypes:

FYPO:0002177 - viable vegetative cell with normal cell morphology

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Genotypes:

Qualitative gene expression

PomGeneEx:0000019 - protein level decreased

References:

PomGeneEx:0000011 - RNA level increased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0000240 - abnormal filament morphology

References:

Genotypes:

FYPO:0003625 - abnormal microtubule cytoskeleton morphology during mitotic interphase

References:

Genotypes:

FYPO:0006875 - abnormal protein localization to cell cortex of cell tip during vegetative growth

References:

Genotypes:

FYPO:0000731 - abnormal protein localization to medial cortex during vegetative growth

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Genotypes:

FYPO:0005800 - abnormal protein movement within plasma membrane during vegetative growth

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Genotypes:

FYPO:0005503 - abnormally monopolar protein localization to cell tip

References:

Genotypes:

FYPO:0001018 - abolished NETO

References:

Genotypes:

FYPO:0007242 - abolished NETO in both daughter cells

References:

Genotypes:

FYPO:0003209 - abolished protein localization to cell tip, with protein mislocalized to cytoplasm

References:

Genotypes:

FYPO:0002128 - abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth

References:

Genotypes:

FYPO:0000705 - abolished protein-protein interaction

References:

Genotypes:

FYPO:0006010 - abolished shmoo contact with partner cell

References:

Genotypes:

FYPO:0006027 - actin cables present in increased numbers

References:

Genotypes:

FYPO:0006030 - actin cortical patches absent from cell

References:

Genotypes:

FYPO:0003327 - curved interphase microtubules

References:

Genotypes:

FYPO:0000016 - curved vegetative cell

References:

Genotypes:

FYPO:0009078 - decreased cell population growth on ethanol carbon source

References:

Genotypes:

FYPO:0001407 - decreased cell population growth on glucose carbon source

References:

Genotypes:

FYPO:0009099 - decreased cell population growth on mannitol carbon source

References:

Genotypes:

FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

References:

Genotypes:

FYPO:0007450 - decreased maintenance of protein location in cell cortex of cell tip

References:

Genotypes:

FYPO:0003150 - decreased NETO

References:

Genotypes:

FYPO:0000929 - decreased protein localization to cell cortex during vegetative growth

References:

Genotypes:

FYPO:0001586 - decreased protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0002556 - decreased protein localization to medial cortex, with protein distributed in cell cortex near non-growing end, during vegetative growth

References:

Genotypes:

FYPO:0003771 - decreased protein localization to plasma membrane of cell tip during vegetative growth

References:

Genotypes:

FYPO:0001645 - decreased protein-protein interaction

References:

Genotypes:

FYPO:0005801 - decreased rate of protein movement within plasma membrane at cell tip

References:

Genotypes:

FYPO:0002021 - dispersed actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0004806 - incomplete cell wall disassembly at cell fusion site

References:

Genotypes:

FYPO:0003938 - increased cell population growth during glucose starvation

References:

Genotypes:

FYPO:0005261 - increased cell population growth on galactose carbon source

References:

Genotypes:

FYPO:0004167 - increased cell population growth on glycerol carbon source

References:

Genotypes:

FYPO:0009074 - increased cell population growth on serine nitrogen source

References:

Genotypes:

FYPO:0003532 - increased monopolar index

References:

Genotypes:

FYPO:0002852 - increased protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0004978 - increased protein localization to new growing cell tip

References:

Genotypes:

FYPO:0002870 - increased protein localization to non-growing cell tip

References:

Genotypes:

FYPO:0001571 - increased protein-protein interaction

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0000339 - mislocalized septum during vegetative growth

References:

Genotypes:

FYPO:0001390 - misoriented septum during vegetative growth

References:

Genotypes:

FYPO:0001019 - monopolar actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0003717 - normal actin cytoskeleton morphology during vegetative growth

References:

Genotypes:

FYPO:0001368 - normal actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0000674 - normal cell population growth at high temperature

References:

Genotypes:

FYPO:0000899 - normal microtubule cytoskeleton organization during vegetative growth

References:

Genotypes:

FYPO:0000833 - normal protein level during vegetative growth

References:

Genotypes:

FYPO:0000644 - normal protein localization during vegetative growth

References:

Genotypes:

FYPO:0007451 - normal protein localization to cell cortex of cell tip during vegetative growth

References:

Genotypes:

FYPO:0002442 - normal protein localization to cell division site

References:

Genotypes:

FYPO:0001587 - normal protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0008003 - normal protein localization to site of mechanical stress

References:

Genotypes:

FYPO:0005828 - normal protein transport along microtubule to cell tip during vegetative growth

References:

Genotypes:

FYPO:0000703 - normal protein-protein interaction

References:

Genotypes:

FYPO:0007398 - normal stress-activated MAPK cascade

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0004730 - protein mislocalized to lateral cell cortex

References:

Genotypes:

FYPO:0000067 - resistance to brefeldin A

References:

Genotypes:

FYPO:0000763 - resistance to cadmium

References:

Genotypes:

FYPO:0009038 - resistance to egtazic acid

References:

Genotypes:

FYPO:0003595 - S-shaped cell

References:

Genotypes:

FYPO:0009067 - sensitive to amorolfine

References:

Genotypes:

FYPO:0000095 - sensitive to bleomycin

References:

Genotypes:

FYPO:0001701 - sensitive to bortezomib

References:

Genotypes:

FYPO:0000096 - sensitive to cadmium

References:

Genotypes:

FYPO:0000097 - sensitive to caffeine during vegetative growth

References:

Genotypes:

FYPO:0000104 - sensitive to cycloheximide

References:

Genotypes:

FYPO:0000842 - sensitive to ethanol during vegetative growth

References:

Genotypes:

FYPO:0000785 - sensitive to formamide

References:

Genotypes:

FYPO:0000087 - sensitive to hydrogen peroxide

References:

Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

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Genotypes:

FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

References:

Genotypes:

FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0000089 - sensitive to methyl methanesulfonate

References:

Genotypes:

FYPO:0003358 - sensitive to miconazole

References:

Genotypes:

FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0009090 - sensitive to sodium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0002701 - sensitive to torin1

References:

Genotypes:

FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

References:

Genotypes:

FYPO:0000945 - swollen spheroid vegetative cell

References:

Genotypes:

FYPO:0002848 - T-shaped cell during recovery from stationary phase

References:

Genotypes:

FYPO:0007379 - T-shaped vegetative cell

References:

Genotypes:

FYPO:0000013 - T-shaped vegetative cell with normal cell length

References:

Genotypes:

FYPO:0002112 - viable curved vegetative cell

References:

Genotypes:

FYPO:0003389 - viable elongated vegetative cell with swollen medial region

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0002104 - viable vegetative cell with normal cell shape

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0000070 - gene structure updated

References:

Protein features

IDNameInterPro nameDB name
PF00018SH3_1SH3_domainPfam
PS50002SH3SH3_domainPROSITE profiles
SM00326SH3SH3_domainSMART
G3DSA:2.30.30.40CATH-Gene3D
SSF50044SH3-like_dom_sfSUPERFAMILY
PTHR47775Polarity_Bud-Selection_RegPANTHER
mobidb-lite-Disorderdisorder_predictionMobiDB-Disorder
mobidb-lite-Low-complexitydisorder_predictionMobiDB-Low-complexity
mobidb-lite-Polardisorder_predictionMobiDB-Polar
mobidb-lite-Polyampholytedisorder_predictionMobiDB-Polyampholyte

Orthologs

References / Literature

PMID:34296454 - The TOR-dependent phosphoproteome and regulation of cellular protein synthesis.
Mak T et al. EMBO J 2021 Aug 16;40(16):e107911
PMID:23615447 - Compartmentalized nodes control mitotic entry signaling in fission yeast.
Deng L et al. Mol Biol Cell 2013 Jun;24(12):1872-81
PANTHER:PTHR13357 - Unknown title
PMID:19646873 - The conserved NDR kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42.
Das M et al. Curr Biol 2009 Aug 11;19(15):1314-9
PMID:21703453 - A phosphorylation cycle shapes gradients of the DYRK family kinase Pom1 at the plasma membrane.
Hachet O et al. Cell 2011 Jun 24;145(7):1116-28
PMID:29930085 - Local and global Cdc42 guanine nucleotide exchange factors for fission yeast cell polarity are coordinated by microtubules and the Tea1-Tea4-Pom1 axis.
Tay YD et al. J Cell Sci 2018 Jul 19;131(14)
PMID:23163955 - Analysis of stress-induced duplex destabilization (SIDD) properties of replication origins, genes and intergenes in the fission yeast, Schizosaccharomyces pombe.
Yadav MP et al. BMC Res Notes 2012 Nov 19;5:643
PMID:15936270 - Wsh3/Tea4 is a novel cell-end factor essential for bipolar distribution of Tea1 and protects cell polarity under environmental stress in S. pombe.
Tatebe H et al. Curr Biol 2005 Jun 07;15(11):1006-15
PMID:39509469 - Rho1 and Rgf1 establish a new actin-dependent signal to determine growth poles in yeast independently of microtubules and the Tea1-Tea4 complex.
Garcia P et al. PLoS Biol 2024 Nov 07;22(11):e3002491
PMID:27984725 - CDK Substrate Phosphorylation and Ordering the Cell Cycle.
Swaffer MP et al. Cell 2016 Dec 15;167(7):1750-1761.e16
PMID:21340088 - Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.
Arita Y et al. Mol Biosyst 2011 May;7(5):1463-72
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:27298342 - Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks.
Willis NA et al. Proc Natl Acad Sci U S A 2016 Jun 28;113(26):E3676-85
PMID:17895368 - Schizosaccharomyces pombe protein phosphatase 1 in mitosis, endocytosis and a partnership with Wsh3/Tea4 to control polarised growth.
Alvarez-Tabarés I et al. J Cell Sci 2007 Oct 15;120(Pt 20):3589-601
PMID:31822915 - Mkt1 is required for RNAi-mediated silencing and establishment of heterochromatin in fission yeast.
Taglini F et al. Nucleic Acids Res 2020 Feb 20;48(3):1239-1253
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:19474792 - Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle.
Martin SG et al. Nature 2009 Jun 11;459(7248):852-6
PMID:19474789 - A spatial gradient coordinates cell size and mitotic entry in fission yeast.
Moseley JB et al. Nature 2009 Jun 11;459(7248):857-60
PMID:26412298 - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.
Beckley JR et al. Mol Cell Proteomics 2015 Dec;14(12):3132-41
PMID:34666001 - Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast.
Neeli-Venkata R et al. Dev Cell 2021 Oct 25;56(20):2856-2870.e7
PMID:21712547 - Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast.
Koch A et al. Sci Signal 2011 Jun 28;4(179):rs6
PMID:16537923 - Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.
Todd BL et al. Mol Cell Biol 2006 Apr;26(7):2817-31
PMID:19542312 - Functional genomics of adhesion, invasion, and mycelial formation in Schizosaccharomyces pombe.
Dodgson J et al. Eukaryot Cell 2009 Aug;8(8):1298-306
PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.
Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704
PMID:19597328 - Role of the protein kinase Kin1 and nuclear centering in actomyosin ring formation in fission yeast.
Cadou A et al. Cell Cycle 2009 Aug;8(15):2451-62
PMID:18684775 - A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.
Kennedy PJ et al. Toxicol Sci 2008 Nov;106(1):124-39
PMID:23093943 - Cytokinesis-based constraints on polarized cell growth in fission yeast.
Bohnert KA et al. PLoS Genet 2012;8(10):e1003004
PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.
Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399
PMID:22137473 - Shaping fission yeast cells by rerouting actin-based transport on microtubules.
Lo Presti L et al. Curr Biol 2011 Dec 20;21(24):2064-9
PMID:26246599 - Phosphorylation-dependent inhibition of Cdc42 GEF Gef1 by 14-3-3 protein Rad24 spatially regulates Cdc42 GTPase activity and oscillatory dynamics during cell morphogenesis.
Das M et al. Mol Biol Cell 2015 Oct 01;26(19):3520-34
PMID:32101745 - Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation.
Lee SY et al. Cell Rep 2020 Feb 25;30(8):2686-2698.e8
PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.
Halova L et al. Open Biol 2021 Apr;11(4):200405
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.
Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963
PMID:28410370 - A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.
Dudin O et al. PLoS Genet 2017 Apr;13(4):e1006721
PMID:18495844 - Interphase microtubule bundles use global cell shape to guide spindle alignment in fission yeast.
Daga RR et al. J Cell Sci 2008 Jun 15;121(Pt 12):1973-80
PMID:25210736 - Dynamics of cell shape inheritance in fission yeast.
Abenza JF et al. PLoS One 2014;9(9):e106959
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.
Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:26525038 - Casein kinase 1γ acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast.
Koyano T et al. Genes Cells 2015 Dec;20(12):1046-58
PMID:39476757 - Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.
Cipak L et al. Biochem Biophys Res Commun 2024 Oct 25;736:150895
PMID:23050226 - A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.
Chen Z et al. G3 (Bethesda) 2012 Oct;2(10):1161-8
PMID:29996109 - Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.
Swaffer MP et al. Cell Rep 2018 Jul 10;24(2):503-514
PMID:29249658 - Mechanisms Connecting the Conserved Protein Kinases Ssp1, Kin1, and Pom1 in Fission Yeast Cell Polarity and Division.
Lee ME et al. Curr Biol 2018 Jan 08;28(1):84-92.e4
PMID:23695164 - Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.
Das J et al. Sci Signal 2013 May 21;6(276):ra38
PMID:15809031 - Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity.
Martin SG et al. Dev Cell 2005 Apr;8(4):479-91
PMID:20870879 - Reorganization of the growth pattern of Schizosaccharomyces pombe in invasive filament formation.
Dodgson J et al. Eukaryot Cell 2010 Nov;9(11):1788-97
PMID:23673619 - Spatial segregation of polarity factors into distinct cortical clusters is required for cell polarity control.
Dodgson J et al. Nat Commun 2013;4:1834
PMID:26443240 - PKA antagonizes CLASP-dependent microtubule stabilization to re-localize Pom1 and buffer cell size upon glucose limitation.
Kelkar M et al. Nat Commun 2015 Oct 07;6:8445
PMID:25837586 - Spontaneous Cdc42 polarization independent of GDI-mediated extraction and actin-based trafficking.
Bendezú FO et al. PLoS Biol 2015 Apr;13(4):e1002097
PMID:36138017 - Ubiquitination of CLIP-170 family protein restrains polarized growth upon DNA replication stress.
Wang X et al. Nat Commun 2022 Sep 22;13(1):5565
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:18257517 - Phosphoproteome analysis of fission yeast.
Wilson-Grady JT et al. J Proteome Res 2008 Mar;7(3):1088-97
PMID:18060866 - ADP-ribosylation factor arf6p may function as a molecular switch of new end take off in fission yeast.
Fujita A Biochem Biophys Res Commun 2008 Feb 01;366(1):193-8
PMID:21652630 - Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.
Snaith HA et al. J Cell Sci 2011 Jul 01;124(Pt 13):2187-99
PMID:24554432 - The Tea4-PP1 landmark promotes local growth by dual Cdc42 GEF recruitment and GAP exclusion.
Kokkoris K et al. J Cell Sci 2014 May 01;127(Pt 9):2005-16
PMID:25373780 - A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.
Graml V et al. Dev Cell 2014 Oct 27;31(2):227-239
PMID:39156640 - Fission yeast Bgs1 glucan synthase participates in the control of growth polarity and membrane traffic.
Ramos M et al. iScience 2024 Aug 16;27(8):110477
PMID:19547744 - Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.
Beltrao P et al. PLoS Biol 2009 Jun 16;7(6):e1000134
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:23907979 - The fission yeast cell wall stress sensor-like proteins Mtl2 and Wsc1 act by turning on the GTPase Rho1p but act independently of the cell wall integrity pathway.
Cruz S et al. Microbiologyopen 2013 Oct;2(5):778-94
PMID:24945319 - CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation.
Vanoosthuyse V et al. PLoS Genet 2014 Jun;10(6):e1004415
PMID:27852900 - Gradients of phosphatidylserine contribute to plasma membrane charge localization and cell polarity in fission yeast.
Haupt A et al. Mol Biol Cell 2017 Jan 01;28(1):210-220
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323