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protein coding gene - mat3-Mc (SPBC1711.02) - mating type M-specific HMG-box DNA-binding transcription factor Mc at silenced MAT3 locus

Gene summary

Standard name
mat3-Mc
Systematic ID
SPBC1711.02
Product
mating type M-specific HMG-box DNA-binding transcription factor Mc at silenced MAT3 locus
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
matMc, mat3Mc, mat3-Mc-silenced, matmc_2
UniProt ID
P0CY16
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome II: 2132849..2133394 forward strand

Annotation

GO biological process

GO:0045944 - positive regulation of transcription by RNA polymerase II

References:

GO cellular component

GO:0005634 - nucleus

References:

GO molecular function

GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

References:

GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

References:

Protein features

PBO:0111928 - mating type M-specific polypeptide matMc

Qualitative gene expression

PomGeneEx:0000011 - RNA level increased

References:

Quantitative gene expression

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0002177 - viable vegetative cell with normal cell morphology

References:

Genotypes:

Protein features

IDNameInterPro nameDB name
PF00505HMG_boxHMG_box_domPFAM
cd01389HMG-box_ROX1-likeCDD
PS50118HMG_BOX_2HMG_box_domPROSITE_PROFILES
SM00398hmgende2HMG_box_domSMART
G3DSA:1.10.30.10:FF:000041FUNFAM
SSF47095HMG-boxHMG_box_dom_sfSUPERFAMILY
G3DSA:1.10.30.10High mobility group box domainHMG_box_dom_sfGENE3D
PTHR10270SOX TRANSCRIPTION FACTORSRY-related_HMG-box_TF-likePANTHER

Orthologs

References / Literature

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323
PMID:26896847 - Ensembl comparative genomics resources.
Herrero J et al. Database (Oxford) 2016;2016
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:38415071 - The Cdc14 phosphatase, Clp1, does not affect genome expression.
Lopez Maury L et al. MicroPubl Biol 2024;2024
PMID:39094565 - Mapping the dynamics of epigenetic adaptation in S. pombe during heterochromatin misregulation.
Larkin A et al. Dev Cell 2024 Jul 26;
PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.
Mata J et al. Nat Genet 2002 Sep;32(1):143-7
PMID:9055078 - Epigenetic inheritance of transcriptional silencing and switching competence in fission yeast.
Thon G et al. Genetics 1997 Mar;145(3):685-96
PMID:15292231 - Regulation of Swi6/HP1-dependent heterochromatin assembly by cooperation of components of the mitogen-activated protein kinase pathway and a histone deacetylase Clr6.
Kim HS et al. J Biol Chem 2004 Oct 08;279(41):42850-9