protein coding gene - mdm34 (SPBC19C2.11c) - ERMES complex subunit, membrane tether and lipid transfer protein Mdm34

Gene summary

Standard name

mdm34

Systematic ID

SPBC19C2.11c

Product

ERMES complex subunit, membrane tether and lipid transfer protein Mdm34

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

Q9UUC9

ORFeome ID

21/21B01

Characterisation status

biological role inferred

Feature type

mRNA gene

Genomic location

chromosome II: 1697447..1699237 reverse strand

Annotation

Protein features

Orthologs

• mdm34 (SJAG_01305) Schizosaccharomyces japonicus
• MDM34 (YGL219C) Saccharomyces cerevisiae

References / Literature

PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.

Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105

PMID:20118936 - Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae.

Lantermann AB et al. Nat Struct Mol Biol 2010 Feb;17(2):251-7

PMID:29432178 - General amino acid control in fission yeast is regulated by a nonconserved transcription factor, with functions analogous to Gcn4/Atf4.

Duncan CDS et al. Proc Natl Acad Sci U S A 2018 Feb 20;115(8):E1829-E1838

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:29279306 - Structure-function insights into direct lipid transfer between membranes by Mmm1-Mdm12 of ERMES.

Kawano S et al. J Cell Biol 2018 Mar 05;217(3):959-974

PMID:26412298 - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Beckley JR et al. Mol Cell Proteomics 2015 Dec;14(12):3132-41

PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.

Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399

GO_REF:0000002 - Comments

PMID:30824696 - Systematic analysis reveals the prevalence and principles of bypassable gene essentiality.

Li J et al. Nat Commun 2019 Mar 01;10(1):1002

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

GO_REF:0000033 - Annotation inferences using phylogenetic trees

PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.

Mata J et al. Nat Genet 2002 Sep;32(1):143-7

GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference

PMID:33483504 - Emr1 regulates the number of foci of the endoplasmic reticulum-mitochondria encounter structure complex.

Rasul F et al. Nat Commun 2021 Jan 22;12(1):521

PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.

Strachan J et al. J Cell Sci 2023 Dec 01;136(23)

PMID:40124504 - Ltc1 localization by EMC regulates cell membrane fluidity to facilitate membrane protein biogenesis.

Berraquero M et al. iScience 2025 Mar 21;28(3):112096

PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.

Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623