protein coding gene - apc10 (SPBC1A4.01) - anaphase-promoting complex substrate recognition subunit Apc10

Gene summary

Standard name

apc10

Systematic ID

SPBC1A4.01

Product

anaphase-promoting complex substrate recognition subunit Apc10

Organism

Schizosaccharomyces pombe (fission yeast)

Synonyms

SPBC1E8.06

UniProt ID

O42971

ORFeome ID

40/40A07

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome II: 1973362..1974265 forward strand

Annotation

Protein features

Orthologs

• ANAPC10 (HGNC:24077) Homo sapiens
• apc10 (SJAG_03561) Schizosaccharomyces japonicus
• DOC1 (YGL240W) Saccharomyces cerevisiae

References / Literature

PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.

Mata J et al. Nat Genet 2002 Sep;32(1):143-7

PMID:31626996 - Multiplexed proteome profiling of carbon source perturbations in two yeast species with SL-SP3-TMT.

Paulo JA et al. J Proteomics 2020 Jan 06;210:103531

PMID:15060174 - Swm1/Apc13 is an evolutionarily conserved subunit of the anaphase-promoting complex stabilizing the association of Cdc16 and Cdc27.

Schwickart M et al. Mol Cell Biol 2004 Apr;24(8):3562-76

PMID:15161942 - The nucleolus is involved in mRNA export from the nucleus in fission yeast.

Ideue T et al. J Cell Sci 2004 Jun 15;117(Pt 14):2887-95

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:34738170 - Overexpression of cell-wall GPI-anchored proteins restores cell growth of N-glycosylation-defective och1 mutants in Schizosaccharomyces pombe.

Fukunaga T et al. Appl Microbiol Biotechnol 2021 Dec;105(23):8771-8781

PMID:15507118 - An interactive gene network for securin-separase, condensin, cohesin, Dis1/Mtc1 and histones constructed by mass transformation.

Yuasa T et al. Genes Cells 2004 Nov;9(11):1069-82

PMID:18082611 - Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1.

Ohi MD et al. Mol Cell 2007 Dec 14;28(5):871-85

PMID:12477395 - Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes.

Yoon HJ et al. Curr Biol 2002 Dec 10;12(23):2048-54

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:18354085 - Diminishing HDACs by drugs or mutations promotes normal or abnormal sister chromatid separation by affecting APC/C and adherin.

Kimata Y et al. J Cell Sci 2008 Apr 01;121(Pt 7):1107-18

PMID:16950791 - Role of Hcn1 and its phosphorylation in fission yeast anaphase-promoting complex/cyclosome function.

Yoon HJ et al. J Biol Chem 2006 Oct 27;281(43):32284-93

PMID:12653962 - A brute force postgenome approach to identify temperature-sensitive mutations that negatively interact with separase and securin plasmids.

Matsumura T et al. Genes Cells 2003 Apr;8(4):341-55

PMID:24463365 - Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.

Rallis C et al. Biol Open 2014 Feb 15;3(2):161-71

PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.

Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105

PMID:28947618 - Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing.

Thakran P et al. EMBO J 2018 Jan 04;37(1):89-101

PMID:31474649 - Identification of 15 New Bypassable Essential Genes of Fission Yeast.

Takeda A et al. Cell Struct Funct 2019 Sep 27;44(2):113-119

PMID:10582241 - Control of metaphase-anaphase progression by proteolysis: cyclosome function regulated by the protein kinase A pathway, ubiquitination and localization.

Yanagida M et al. Philos Trans R Soc Lond B Biol Sci 1999 Sep 29;354(1389):1559-69; discussion 1569-70

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:9736616 - Apc10 and Ste9/Srw1, two regulators of the APC-cyclosome, as well as the CDK inhibitor Rum1 are required for G1 cell-cycle arrest in fission yeast.

Kominami K et al. EMBO J 1998 Sep 15;17(18):5388-99

PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704

PMID:30355493 - Expanded Interactome of the Intrinsically Disordered Protein Dss1.

Schenstrøm SM et al. Cell Rep 2018 Oct 23;25(4):862-870

PMID:18556659 - The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).

Sczaniecka M et al. J Biol Chem 2008 Aug 22;283(34):23039-47

PMID:11033806 - [Overexpression of the apc10+ gene in the fission yeast Schizosaccharomyces pombe can suppress temperature sensitivity of the nuc2-663 mutant,but not its sterility].

Grishchuk EL et al. Mol Biol (Mosk) 2000;34(5):809-15

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83