protein coding gene - blt1 (SPBC1A4.05) - cortical scaffold protein Blt1

Gene summary

Standard name

blt1

Systematic ID

SPBC1A4.05

Product

cortical scaffold protein Blt1

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

O74338

ORFeome ID

37/37F05

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome II: 1984466..1988552 forward strand

Annotation

Protein features

Orthologs

• blt1 (SJAG_03564) Schizosaccharomyces japonicus

References / Literature

PMID:23349808 - Fission yeast Nod1 is a component of cortical nodes involved in cell size control and division site placement.

Jourdain I et al. PLoS One 2013;8(1):e54142

PMID:34250083 - Barcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast.

Romila CA et al. Microb Cell 2021 Jul 05;8(7):146-160

PMID:12153582 - Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe.

Soto T et al. Eur J Biochem 2002 Aug;269(15):3847-55

PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.

Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:21712547 - Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast.

Koch A et al. Sci Signal 2011 Jun 28;4(179):rs6

PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.

Strachan J et al. J Cell Sci 2023 Dec 01;136(23)

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.

Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.

Rodríguez-López M et al. Elife 2023 Oct 03;12

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:24957674 - Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Anver S et al. EMBO Rep 2014 Aug;15(8):894-902

PMID:21504829 - Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Stewart EV et al. Mol Cell 2011 Apr 22;42(2):160-71

PMID:30853434 - NDR Kinase Sid2 Drives Anillin-like Mid1 from the Membrane to Promote Cytokinesis and Medial Division Site Placement.

Willet AH et al. Curr Biol 2019 Mar 18;29(6):1055-1063.e2

PMID:29996109 - Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.

Swaffer MP et al. Cell Rep 2018 Jul 10;24(2):503-514

PMID:24790095 - Characterization of the roles of Blt1p in fission yeast cytokinesis.

Goss JW et al. Mol Biol Cell 2014 Jul 01;25(13):1946-57

PMID:18257517 - Phosphoproteome analysis of fission yeast.

Wilson-Grady JT et al. J Proteome Res 2008 Mar;7(3):1088-97

PMID:19547744 - Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Beltrao P et al. PLoS Biol 2009 Jun 16;7(6):e1000134

PMID:23615450 - Separate roles of IQGAP Rng2p in forming and constricting the Schizosaccharomyces pombe cytokinetic contractile ring.

Tebbs IR et al. Mol Biol Cell 2013 Jun;24(12):1904-17

PMID:27298342 - Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks.

Willis NA et al. Proc Natl Acad Sci U S A 2016 Jun 28;113(26):E3676-85

PMID:29722930 - Septins regulate the equatorial dynamics of the separation initiation network kinase Sid2p and glucan synthases to ensure proper cytokinesis.

Zheng S et al. FEBS J 2018 Jul;285(13):2468-2480

PMID:14655046 - Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast.

Miki F et al. Mol Genet Genomics 2004 Jan;270(6):449-61

PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704

PMID:28410370 - A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Dudin O et al. PLoS Genet 2017 Apr;13(4):e1006721

PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.

Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399

PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.

Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87

PMID:19474792 - Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle.

Martin SG et al. Nature 2009 Jun 11;459(7248):852-6

PMID:27168121 - Discovery of genes involved in mitosis, cell division, cell wall integrity and chromosome segregation through construction of Schizosaccharomyces pombe deletion strains.

Chen JS et al. Yeast 2016 Sep;33(9):507-17

PMID:31276301 - A unique kinesin-like protein, Klp8, is involved in mitosis and cell morphology through microtubule stabilization.

Kashiwazaki J et al. Cytoskeleton (Hoboken) 2019 May;76(5):355-367

PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.

Halova L et al. Open Biol 2021 Apr;11(4):200405

PMID:39476757 - Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.

Cipak L et al. Biochem Biophys Res Commun 2024 Oct 25;736:150895

PMID:23149940 - Blt1 and Mid1 provide overlapping membrane anchors to position the division plane in fission yeast.

Guzman-Vendrell M et al. Mol Cell Biol 2013 Jan;33(2):418-28

PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.

Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:20625380 - A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length.

Liu NN et al. Cell Res 2010 Aug;20(8):963-5

PMID:23297348 - Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.

Chen JS et al. Mol Cell Proteomics 2013 May;12(5):1074-86

PMID:28914606 - Nanoscale architecture of the Schizosaccharomyces pombe contractile ring.

McDonald NA et al. Elife 2017 Sep 15;6

PMID:19474789 - A spatial gradient coordinates cell size and mitotic entry in fission yeast.

Moseley JB et al. Nature 2009 Jun 11;459(7248):857-60

PMID:28539404 - Analysis of interphase node proteins in fission yeast by quantitative and superresolution fluorescence microscopy.

Akamatsu M et al. Mol Biol Cell 2017 Nov 07;28(23):3203-3214

PMID:22918943 - Anillin-related protein Mid1p coordinates the assembly of the cytokinetic contractile ring in fission yeast.

Saha S et al. Mol Biol Cell 2012 Oct;23(20):3982-92

PMID:27206859 - TOR complex 2 localises to the cytokinetic actomyosin ring and controls the fidelity of cytokinesis.

Baker K et al. J Cell Sci 2016 Jul 01;129(13):2613-24

PMID:31041892 - Fission yeast type 2 node proteins Blt1p and Gef2p cooperate to ensure timely completion of cytokinesis.

Kwon L et al. BMC Mol Cell Biol 2019 Jan 24;20(1):1

PMID:21849474 - Spatial control of Cdc42 activation determines cell width in fission yeast.

Kelly FD et al. Mol Biol Cell 2011 Oct;22(20):3801-11

PMID:24508166 - Dueling kinases regulate cell size at division through the SAD kinase Cdr2.

Deng L et al. Curr Biol 2014 Feb 17;24(4):428-33

PMID:31217286 - Increasing ergosterol levels delays formin-dependent assembly of F-actin cables and disrupts division plane positioning in fission yeast.

Arbizzani F et al. J Cell Sci 2019 Jul 01;132(13)