protein coding gene - nda3 (SPBC26H8.07c) - tubulin beta Nda3

Gene summary

Standard name

nda3

Systematic ID

SPBC26H8.07c

Product

tubulin beta Nda3

Organism

Schizosaccharomyces pombe (fission yeast)

Synonyms

ben1, alp12

UniProt ID

P05219

ORFeome ID

33/33C09

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome II: 3964092..3965973 reverse strand

Annotation

Protein features

Orthologs

• TUBB2A (HGNC:12412) Homo sapiens
• TUBB1 (HGNC:16257) Homo sapiens
• TUBB4B (HGNC:20771) Homo sapiens
• TUBB3 (HGNC:20772) Homo sapiens
• TUBB8 (HGNC:20773) Homo sapiens
• TUBB4A (HGNC:20774) Homo sapiens
• TUBB6 (HGNC:20776) Homo sapiens
• TUBB (HGNC:20778) Homo sapiens
• TUBB2B (HGNC:30829) Homo sapiens
• nda3 (SJAG_04003) Schizosaccharomyces japonicus
• TUB2 (YFL037W) Saccharomyces cerevisiae

References / Literature

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:15743909 - Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast.

Kovar DR et al. Mol Biol Cell 2005 May;16(5):2313-24

GO_REF:0000051 - S. pombe keyword mapping

PMID:22375062 - Plo1 phosphorylates Dam1 to promote chromosome bi-orientation in fission yeast.

Buttrick GJ et al. J Cell Sci 2012 Apr 01;125(Pt 7):1645-51

PMID:22521786 - Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint.

Shepperd LA et al. Curr Biol 2012 May 22;22(10):891-9

PMID:32168916 - Human Cancer-Associated Mutations of SF3B1 Lead to a Splicing Modification of Its Own RNA.

Bergot T et al. Cancers (Basel) 2020 Mar 11;12(3)

PMID:16738311 - Fission yeast Cid12 has dual functions in chromosome segregation and checkpoint control.

Win TZ et al. Mol Cell Biol 2006 Jun;26(12):4435-47

PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.

Strachan J et al. J Cell Sci 2023 Dec 01;136(23)

PMID:12007420 - Tea3p is a cell end marker activating polarized growth in Schizosaccharomyces pombe.

Arellano M et al. Curr Biol 2002 Apr 30;12(9):751-6

PMID:9223296 - The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex.

He X et al. Proc Natl Acad Sci U S A 1997 Jul 22;94(15):7965-70

PMID:8887647 - Fission yeast mal2+ is required for chromosome segregation.

Fleig U et al. Mol Cell Biol 1996 Nov;16(11):6169-77

PMID:9450991 - Essential role of tubulin-folding cofactor D in microtubule assembly and its association with microtubules in fission yeast.

Hirata D et al. EMBO J 1998 Feb 02;17(3):658-66

PMID:9745017 - Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutants.

Potashkin J et al. Curr Genet 1998 Sep;34(3):153-63

PMID:10905343 - Characterisation of fission yeast alp11 mutants defines three functional domains within tubulin-folding cofactor B.

Radcliffe PA et al. Mol Gen Genet 2000 Jun;263(5):752-60

PMID:8834798 - Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring.

Chang F et al. J Cell Sci 1996 Jan;109 ( Pt 1):131-42

PMID:9658169 - Identification of novel temperature-sensitive lethal alleles in essential beta-tubulin and nonessential alpha 2-tubulin genes as fission yeast polarity mutants.

Radcliffe P et al. Mol Biol Cell 1998 Jul;9(7):1757-71

PMID:8972853 - Fission yeast genes which disrupt mitotic chromosome segregation when overexpressed.

Javerzat JP et al. Nucleic Acids Res 1996 Dec 01;24(23):4676-83

PMID:11432827 - Fission yeast ch-TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpoint.

Garcia MA et al. EMBO J 2001 Jul 02;20(13):3389-401

PMID:19217403 - Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.

Williams JS et al. Mol Cell 2009 Feb 13;33(3):287-98

PMID:8937982 - Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function.

Ekwall K et al. J Cell Sci 1996 Nov;109 ( Pt 11):2637-48

PMID:16394105 - The V260I mutation in fission yeast alpha-tubulin Atb2 affects microtubule dynamics and EB1-Mal3 localization and activates the Bub1 branch of the spindle checkpoint.

Asakawa K et al. Mol Biol Cell 2006 Mar;17(3):1421-35

PMID:41354344 - The mitotic functions of a fission yeast CK1 enzyme are regulated by Cdk1-dependent and auto-phosphorylation.

Akizuki K et al. J Biol Chem 2025 Dec 05;:111007

PMID:12719471 - Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation.

Pidoux AL et al. J Cell Biol 2003 Apr 28;161(2):295-307

PMID:11359928 - Identification of two type V myosins in fission yeast, one of which functions in polarized cell growth and moves rapidly in the cell.

Motegi F et al. Mol Biol Cell 2001 May;12(5):1367-80

PMID:23770679 - Microtubules and Alp7-Alp14 (TACC-TOG) reposition chromosomes before meiotic segregation.

Kakui Y et al. Nat Cell Biol 2013 Jul;15(7):786-96

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:6094012 - The NDA3 gene of fission yeast encodes beta-tubulin: a cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis.

Hiraoka Y et al. Cell 1984 Dec;39(2 Pt 1):349-58

PMID:10978278 - The cofactor-dependent pathways for alpha- and beta-tubulins in microtubule biogenesis are functionally different in fission yeast.

Radcliffe PA et al. Genetics 2000 Sep;156(1):93-103

PMID:3040264 - DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe.

Uemura T et al. Cell 1987 Sep 11;50(6):917-25

PMID:15509783 - Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p.

Vanoosthuyse V et al. Mol Cell Biol 2004 Nov;24(22):9786-801

PMID:21540296 - Condensin phosphorylated by the Aurora-B-like kinase Ark1 is continuously required until telophase in a mode distinct from Top2.

Nakazawa N et al. J Cell Sci 2011 Jun 01;124(Pt 11):1795-807

PMID:22730331 - Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions.

Nie M et al. J Biol Chem 2012 Aug 24;287(35):29610-9

PMID:29742018 - The kinase domain of CK1 enzymes contains the localization cue essential for compartmentalized signaling at the spindle pole.

Elmore ZC et al. Mol Biol Cell 2018 Jul 01;29(13):1664-1674

PMID:9573052 - Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis.

Bähler J et al. Genes Dev 1998 May 01;12(9):1356-70

PMID:6887245 - Cell division cycle genes nda2 and nda3 of the fission yeast Schizosaccharomyces pombe control microtubular organization and sensitivity to anti-mitotic benzimidazole compounds.

Umesono K et al. J Mol Biol 1983 Aug 05;168(2):271-84

PMID:11861765 - Fission yeast Pds5 is required for accurate chromosome segregation and for survival after DNA damage or metaphase arrest.

Wang SW et al. J Cell Sci 2002 Feb 01;115(Pt 3):587-98

PMID:33506191 - Escape from mitotic catastrophe by actin-dependent nuclear displacement in fission yeast.

Yukawa M et al. iScience 2021 Jan 22;24(1):102031

PMID:15126629 - Suppression of a mitotic mutant by tRNA-Ala anticodon mutations that produce a dominant defect in late mitosis.

Kimata Y et al. J Cell Sci 2004 May 01;117(Pt 11):2283-93

PMID:2274023 - Molecular basis for determining the sensitivity of eucaryotes to the antimitotic drug rhizoxin.

Takahashi M et al. Mol Gen Genet 1990 Jul;222(2-3):169-75

PMID:31719112 - Checkpoint Regulation of Nuclear Tos4 Defines S Phase Arrest in Fission Yeast.

Kim SM et al. G3 (Bethesda) 2020 Jan 07;10(1):255-266

PMID:14742702 - Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation.

Sato M et al. Mol Biol Cell 2004 Apr;15(4):1609-22

PMID:10459013 - Sid2p, a spindle pole body kinase that regulates the onset of cytokinesis.

Sparks CA et al. J Cell Biol 1999 Aug 23;146(4):777-90

PMID:8876193 - Microtubules mediate mitochondrial distribution in fission yeast.

Yaffe MP et al. Proc Natl Acad Sci U S A 1996 Oct 15;93(21):11664-8

PMID:16950131 - Phospho-regulation of the Cdc14/Clp1 phosphatase delays late mitotic events in S. pombe.

Wolfe BA et al. Dev Cell 2006 Sep;11(3):423-30

PMID:22540037 - Predicting the fission yeast protein interaction network.

Pancaldi V et al. G3 (Bethesda) 2012 Apr;2(4):453-67

PMID:37445861 - Resistance to Chemotherapeutic 5-Fluorouracil Conferred by Modulation of Heterochromatic Integrity through Ino80 Function in Fission Yeast.

Lim KK et al. Int J Mol Sci 2023 Jun 26;24(13)

PMID:19373772 - The dynamin related protein Dnm1 fragments mitochondria in a microtubule-dependent manner during the fission yeast cell cycle.

Jourdain I et al. Cell Motil Cytoskeleton 2009 Aug;66(8):509-23

PMID:19592249 - A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism.

Vanoosthuyse V et al. Curr Biol 2009 Jul 28;19(14):1176-81

PMID:11350031 - Mutation in the prp12+ gene encoding a homolog of SAP130/SF3b130 causes differential inhibition of pre-mRNA splicing and arrest of cell-cycle progression in Schizosaccharomyces pombe.

Habara Y et al. RNA 2001 May;7(5):671-81

PMID:16467379 - Actin-depolymerizing protein Adf1 is required for formation and maintenance of the contractile ring during cytokinesis in fission yeast.

Nakano K et al. Mol Biol Cell 2006 Apr;17(4):1933-45

PMID:6887244 - Cold-sensitive nuclear division arrest mutants of the fission yeast Schizosaccharomyces pombe.

Toda T et al. J Mol Biol 1983 Aug 05;168(2):251-70

PMID:10769212 - Molecular mechanism of myosin-II assembly at the division site in Schizosaccharomyces pombe.

Motegi F et al. J Cell Sci 2000 May;113 ( Pt 10):1813-25

PMID:27350684 - Mutant allele of rna14 in fission yeast affects pre-mRNA splicing.

Yadav S et al. J Genet 2016 Jun;95(2):389-97

PMID:39747188 - PhpC NF-Y transcription factor infiltrates heterochromatin to generate cryptic intron-containing transcripts crucial for small RNA production.

Srivastav MK et al. Nat Commun 2025 Jan 02;16(1):268

PMID:27834216 - Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism.

Britto M et al. Proc Natl Acad Sci U S A 2016 Nov 22;113(47):E7483-E7489

PMID:26900649 - The hairpin region of Ndc80 is important for the kinetochore recruitment of Mph1/MPS1 in fission yeast.

Chmielewska AE et al. Cell Cycle 2016;15(5):740-7

PMID:8211184 - U2AF homolog required for splicing in vivo.

Potashkin J et al. Science 1993 Oct 22;262(5133):573-5

PMID:28366744 - Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest.

May KM et al. Curr Biol 2017 Apr 24;27(8):1221-1228

PMID:26412298 - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Beckley JR et al. Mol Cell Proteomics 2015 Dec;14(12):3132-41

PMID:19330768 - Tubulin heterodimers remain functional for one cell cycle after the inactivation of tubulin-folding cofactor D in fission yeast cells.

Fedyanina OS et al. Yeast 2009 Apr;26(4):235-47

PMID:11909965 - Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner.

Millband DN et al. Mol Cell Biol 2002 Apr;22(8):2728-42

PMID:17036054 - Microtubule depolymerization can drive poleward chromosome motion in fission yeast.

Grishchuk EL et al. EMBO J 2006 Oct 18;25(20):4888-96

GO_REF:0000050 - Manual transfer of GO annotation data to genes by curator judgment of sequence model

PMID:8978687 - The fission yeast dma1 gene is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised.

Murone M et al. EMBO J 1996 Dec 02;15(23):6605-16

PMID:15128870 - A role for the Cdc14-family phosphatase Flp1p at the end of the cell cycle in controlling the rapid degradation of the mitotic inducer Cdc25p in fission yeast.

Esteban V et al. J Cell Sci 2004 May 15;117(Pt 12):2461-8

PMID:22281223 - Kinase activity of fission yeast Mph1 is required for Mad2 and Mad3 to stably bind the anaphase promoting complex.

Zich J et al. Curr Biol 2012 Feb 21;22(4):296-301

PMID:9892665 - Moe1, a conserved protein in Schizosaccharomyces pombe, interacts with a Ras effector, Scd1, to affect proper spindle formation.

Chen CR et al. Proc Natl Acad Sci U S A 1999 Jan 19;96(2):517-22

PMID:7003311 - Genetic analysis of resistant mutants to antimitotic benzimidazole compounds in Schizosaccharomyces pombe.

Yamamoto M Mol Gen Genet 1980;180(1):231-4

PMID:16481403 - The fission yeast transforming acidic coiled coil-related protein Mia1p/Alp7p is required for formation and maintenance of persistent microtubule-organizing centers at the nuclear envelope.

Zheng L et al. Mol Biol Cell 2006 May;17(5):2212-22

PMID:11950879 - Control of localization of a spindle checkpoint protein, Mad2, in fission yeast.

Ikui AE et al. J Cell Sci 2002 Apr 15;115(Pt 8):1603-10

PMID:10775265 - The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeast.

Guertin DA et al. EMBO J 2000 Apr 17;19(8):1803-15

PMID:22696680 - Fission yeast Alp14 is a dose-dependent plus end-tracking microtubule polymerase.

Al-Bassam J et al. Mol Biol Cell 2012 Aug;23(15):2878-90

PMID:26804021 - Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing.

Tashiro S et al. Nat Commun 2016 Jan 25;7:10393

PMID:6327053 - Identification of the pleiotropic cell division cycle gene NDA2 as one of two different alpha-tubulin genes in Schizosaccharomyces pombe.

Toda T et al. Cell 1984 May;37(1):233-42

PMID:34805795 - The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability.

Calvo IA et al. iScience 2021 Nov 19;24(11):103338

PMID:27664031 - C-terminal region of Mad2 plays an important role during mitotic spindle checkpoint in fission yeast Schizosaccharomyces pombe.

Singh GK et al. Mol Biol Rep 2017 Feb;44(1):89-96

PMID:15936270 - Wsh3/Tea4 is a novel cell-end factor essential for bipolar distribution of Tea1 and protects cell polarity under environmental stress in S. pombe.

Tatebe H et al. Curr Biol 2005 Jun 07;15(11):1006-15

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

PMID:7334057 - Sequential alterations in the nuclear chromatin region during mitosis of the fission yeast Schizosaccharomyces pombe: video fluorescence microscopy of synchronously growing wild-type and cold-sensitive cdc mutants by using a DNA-binding fluorescent probe.

Toda T et al. J Cell Sci 1981 Dec;52:271-87

PMID:11694585 - Interactions among a fimbrin, a capping protein, and an actin-depolymerizing factor in organization of the fission yeast actin cytoskeleton.

Nakano K et al. Mol Biol Cell 2001 Nov;12(11):3515-26

PMID:12234926 - Fission yeast Mor2/Cps12, a protein similar to Drosophila Furry, is essential for cell morphogenesis and its mutation induces Wee1-dependent G(2) delay.

Hirata D et al. EMBO J 2002 Sep 16;21(18):4863-74

PMID:24963130 - The KASH protein Kms2 coordinates mitotic remodeling of the spindle pole body.

Wälde S et al. J Cell Sci 2014 Aug 15;127(Pt 16):3625-40

PMID:21664573 - Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors.

Meadows JC et al. Dev Cell 2011 Jun 14;20(6):739-50

PMID:30810475 - Early splicing functions of fission yeast Prp16 and its unexpected requirement for gene Silencing is governed by intronic features.

Vijayakumari D et al. RNA Biol 2019 Jun;16(6):754-769

PMID:12796296 - Scw1p antagonizes the septation initiation network to regulate septum formation and cell separation in the fission yeast Schizosaccharomyces pombe.

Jin QW et al. Eukaryot Cell 2003 Jun;2(3):510-20

PMID:24173154 - Visualization of chromosomes in mitotically arrested cells of the fission yeast Schizosaccharomyces pombe.

Umesono K et al. Curr Genet 1983 Apr;7(2):123-8

PMID:18272786 - Pxl1p, a paxillin-related protein, stabilizes the actomyosin ring during cytokinesis in fission yeast.

Ge W et al. Mol Biol Cell 2008 Apr;19(4):1680-92

PMID:22500803 - EBs recognize a nucleotide-dependent structural cap at growing microtubule ends.

Maurer SP et al. Cell 2012 Apr 13;149(2):371-82

PMID:9601094 - Mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe.

He X et al. J Cell Sci 1998 Jun;111 ( Pt 12):1635-47

PMID:16824200 - Schizosaccharomyces pombe homolog of Survivin, Bir1p, exhibits a novel dynamic behavior at the spindle mid-zone.

Rajagopalan S et al. Genes Cells 2006 Jul;11(7):815-27

PMID:21856157 - mmb1p binds mitochondria to dynamic microtubules.

Fu C et al. Curr Biol 2011 Sep 13;21(17):1431-9

PMID:11309419 - A mechanism for nuclear positioning in fission yeast based on microtubule pushing.

Tran PT et al. J Cell Biol 2001 Apr 16;153(2):397-411

PMID:18362178 - Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis.

Nakazawa N et al. J Cell Biol 2008 Mar 24;180(6):1115-31

PMID:22119525 - SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast.

Singh NS et al. Curr Biol 2011 Dec 06;21(23):1968-78

PMID:25274039 - A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast.

Bayne EH et al. Genome Biol 2014;15(10):481

PMID:2665944 - Regulation of p34cdc2 protein kinase during mitosis.

Moreno S et al. Cell 1989 Jul 28;58(2):361-72

PMID:34402513 - Phosphorylation in the intrinsically disordered region of F-BAR protein Imp2 regulates its contractile ring recruitment.

Willet AH et al. J Cell Sci 2021 Aug 15;134(16)

PMID:36108046 - Recovery from spindle checkpoint-mediated arrest requires a novel Dnt1-dependent APC/C activation mechanism.

Bai S et al. PLoS Genet 2022 Sep;18(9):e1010397

PMID:9722643 - The fission yeast chromo domain encoding gene chp1(+) is required for chromosome segregation and shows a genetic interaction with alpha-tubulin.

Doe CL et al. Nucleic Acids Res 1998 Sep 15;26(18):4222-9

PMID:9917066 - Molecular genetic analysis of U2AF59 in Schizosaccharomyces pombe: differential sensitivity of introns to mutational inactivation.

Romfo CM et al. RNA 1999 Jan;5(1):49-65

PMID:19846658 - Bub3p facilitates spindle checkpoint silencing in fission yeast.

Vanoosthuyse V et al. Mol Biol Cell 2009 Dec;20(24):5096-105

PMID:12791993 - Equatorial retention of the contractile actin ring by microtubules during cytokinesis.

Pardo M et al. Science 2003 Jun 06;300(5625):1569-74

PMID:18418059 - The Flp1/Clp1 phosphatase cooperates with HECT-type Pub1/2 protein-ubiquitin ligases in Schizosaccharomyces pombe.

Esteban V et al. Cell Cycle 2008 May 01;7(9):1269-76

PMID:25002536 - A novel histone deacetylase complex in the control of transcription and genome stability.

Zilio N et al. Mol Cell Biol 2014 Sep 15;34(18):3500-14

PMID:9763447 - cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe.

West RR et al. Mol Biol Cell 1998 Oct;9(10):2839-55

PMID:20375067 - Fission yeast Rad26ATRIP delays spindle-pole-body separation following interphase microtubule damage.

Herring M et al. J Cell Sci 2010 May 01;123(Pt 9):1537-45

PMID:20976105 - Silencing mediated by the Schizosaccharomyces pombe HIRA complex is dependent upon the Hpc2-like protein, Hip4.

Anderson HE et al. PLoS One 2010 Oct 18;5(10):e13488

PMID:27618268 - Bub3-Bub1 Binding to Spc7/KNL1 Toggles the Spindle Checkpoint Switch by Licensing the Interaction of Bub1 with Mad1-Mad2.

Mora-Santos MD et al. Curr Biol 2016 Oct 10;26(19):2642-2650

PMID:12653963 - The small GTPase Rho4 is involved in controlling cell morphology and septation in fission yeast.

Nakano K et al. Genes Cells 2003 Apr;8(4):357-70

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:9200612 - tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell.

Mata J et al. Cell 1997 Jun 13;89(6):939-49

PMID:2211869 - The transition of cells of the fission yeast beta-tubulin mutant nda3-311 as seen by freeze-substitution electron microscopy. Requirement of functional tubulin for spindle pole body duplication.

Kanbe T et al. J Cell Sci 1990 Jun;96 ( Pt 2):275-82

PMID:26152728 - A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.

Mathiassen SG et al. J Biol Chem 2015 Aug 21;290(34):21141-21153

PMID:29235477 - Nucleotide- and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics.

von Loeffelholz O et al. Nat Commun 2017 Dec 13;8(1):2110

PMID:15371542 - The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association.

Kerres A et al. Mol Biol Cell 2004 Dec;15(12):5255-67

PMID:33925026 - Dual Impact of a Benzimidazole Resistant β-Tubulin on Microtubule Behavior in Fission Yeast.

Minagawa M et al. Cells 2021 Apr 28;10(5)

PMID:34798057 - Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation.

Finet O et al. Mol Cell 2022 Jan 20;82(2):404-419.e9

PMID:20967237 - Fission yeast cells undergo nuclear division in the absence of spindle microtubules.

Castagnetti S et al. PLoS Biol 2010 Oct 12;8(10):e1000512

PMID:26864000 - Alp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism.

Hussmann F et al. Sci Rep 2016 Feb 11;6:20653

PMID:30659798 - Cryo-EM Structure (4.5-Å) of Yeast Kinesin-5-Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance.

von Loeffelholz O et al. J Mol Biol 2019 Feb 15;431(4):864-872

PMID:8388878 - Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast.

Funabiki H et al. J Cell Biol 1993 Jun;121(5):961-76

PMID:11063680 - Fission yeast Ras1 effector Scd1 interacts with the spindle and affects its proper formation.

Li YC et al. Genetics 2000 Nov;156(3):995-1004

PMID:12546793 - Mitotic hyperphosphorylation of the fission yeast SIN scaffold protein cdc11p is regulated by the protein kinase cdc7p.

Krapp A et al. Curr Biol 2003 Jan 21;13(2):168-72

PMID:9755169 - Cdc18 transcription and proteolysis couple S phase to passage through mitosis.

Baum B et al. EMBO J 1998 Oct 01;17(19):5689-98

PMID:15797925 - The nuclear rim protein Amo1 is required for proper microtubule cytoskeleton organisation in fission yeast.

Pardo M et al. J Cell Sci 2005 Apr 15;118(Pt 8):1705-14

PMID:9167972 - Microtubule-associated coiled-coil protein Ssm4 is involved in the meiotic development in fission yeast.

Yamashita A et al. Genes Cells 1997 Feb;2(2):155-66

PMID:22264709 - TUBA1A mutation-associated lissencephaly: case report and review of the literature.

Sohal AP et al. Pediatr Neurol 2012 Feb;46(2):127-31

PMID:12479804 - Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN).

Guertin DA et al. Dev Cell 2002 Dec;3(6):779-90

PMID:9679144 - Regulation of cell polarity by microtubules in fission yeast.

Sawin KE et al. J Cell Biol 1998 Jul 27;142(2):457-71

PMID:15647375 - The roles of fission yeast ase1 in mitotic cell division, meiotic nuclear oscillation, and cytokinesis checkpoint signaling.

Yamashita A et al. Mol Biol Cell 2005 Mar;16(3):1378-95

PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.

Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:19454013 - Conserved features of cohesin binding along fission yeast chromosomes.

Schmidt CK et al. Genome Biol 2009;10(5):R52

PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.

Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101

PMID:16478992 - Requirement of fission yeast Cid14 in polyadenylation of rRNAs.

Win TZ et al. Mol Cell Biol 2006 Mar;26(5):1710-21

GO_REF:0000002 - Comments

PMID:9348288 - Mal3, the fission yeast homologue of the human APC-interacting protein EB-1 is required for microtubule integrity and the maintenance of cell form.

Beinhauer JD et al. J Cell Biol 1997 Nov 03;139(3):717-28

PMID:10418128 - Effects of pressure stress on the fission yeast Schizosaccharomyces pombe cold-sensitive mutant nda3.

Sato M et al. FEMS Microbiol Lett 1999 Jul 01;176(1):31-8

PMID:28218250 - Chromatin remodeller Fun30 Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Lee J et al. Nat Commun 2017 Feb 20;8:14527

PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs

PMID:3409871 - Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis.

Ohkura H et al. EMBO J 1988 May;7(5):1465-73

PMID:8665408 - Mutational analysis of U1 function in Schizosaccharomyces pombe: pre-mRNAs differ in the extent and nature of their requirements for this snRNA in vivo.

Alvarez CJ et al. RNA 1996 May;2(5):404-18

PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.

Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7

PMID:30463883 - Suppressor Analysis Uncovers That MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly in Schizosaccharomyces pombe .

Yukawa M et al. G3 (Bethesda) 2019 Jan 09;9(1):269-280

PMID:27146110 - Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast.

Gergely ZR et al. Mol Biol Cell 2016 Nov 07;27(22):3490-3514