PomBase home

protein coding gene - gpi15 (SPBC685.05) - pig-H

Gene summary

Standard name
gpi15
Systematic ID
SPBC685.05
Product
pig-H
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
Q9Y7L7
ORFeome ID
42/42G06
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome II: 2777780..2778628 forward strand

Annotation

PBO:0003560 - 2.4.1.198

Disease association

MONDO:0060724 - glycosylphosphatidylinositol biosynthesis defect 17

References:

GO biological process

GO:0006506 - GPI anchor biosynthetic process

References:

GO cellular component

GO:0005783 - endoplasmic reticulum

References:

GO:0000506 - glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex

References:

GO molecular function

GO:0017176 - phosphatidylinositol N-acetylglucosaminyltransferase activity

References:

Protein sequence feature

SO:0000418 - signal_peptide

SO:0001812 - transmembrane_helix

References:

Quantitative gene expression

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002420 - inviable after spore germination, single cell division, abnormal cell shape

References:

Genotypes:

FYPO:0002151 - inviable spore

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF10181PIG-HPIGH-H_domPfam
PTHR15231PIG-HPANTHER
Transmembrane alpha helixDeepTMHMM

Orthologs

References / Literature

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:11152613 - Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
Krogh A et al. J Mol Biol 2001 Jan 19;305(3):567-80
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053