protein coding gene - cnd1 (SPBC776.13) - condensin complex non-SMC subunit Cnd1

Gene summary

Standard name

cnd1

Systematic ID

SPBC776.13

Product

condensin complex non-SMC subunit Cnd1

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

O94679

ORFeome ID

49/49G08

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome II: 3200088..3203986 forward strand

Annotation

Protein features

Orthologs

• NCAPD2 (HGNC:24305) Homo sapiens
• cnd1 (SJAG_03161) Schizosaccharomyces japonicus
• YCS4 (YLR272C) Saccharomyces cerevisiae

References / Literature

PMID:25847133 - RNA pol II transcript abundance controls condensin accumulation at mitotically up-regulated and heat-shock-inducible genes in fission yeast.

Nakazawa N et al. Genes Cells 2015 Jun;20(6):481-99

PMID:37820734 - Establishment of dsDNA-dsDNA interactions by the condensin complex.

Tang M et al. Mol Cell 2023 Nov 02;83(21):3787-3800.e9

PMID:10485849 - Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4.

Sutani T et al. Genes Dev 1999 Sep 01;13(17):2271-83

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:21712547 - Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast.

Koch A et al. Sci Signal 2011 Jun 28;4(179):rs6

PMID:25520186 - ATPase-dependent auto-phosphorylation of the open condensin hinge diminishes DNA binding.

Akai Y et al. Open Biol 2014 Dec;4(12)

PMID:33176152 - Acute Heat Stress Leads to Reversible Aggregation of Nuclear Proteins into Nucleolar Rings in Fission Yeast.

Gallardo P et al. Cell Rep 2020 Nov 10;33(6):108377

PMID:12000964 - Cnd2 has dual roles in mitotic condensation and interphase.

Aono N et al. Nature 2002 May 09;417(6885):197-202

PMID:23263988 - Quantitative analysis of chromosome condensation in fission yeast.

Petrova B et al. Mol Cell Biol 2013 Mar;33(5):984-98

GO_REF:0000033 - Annotation inferences using phylogenetic trees

PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.

Halova L et al. Open Biol 2021 Apr;11(4):200405

PMID:26537787 - Targeting of SUMO substrates to a Cdc48-Ufd1-Npl4 segregase and STUbL pathway in fission yeast.

Køhler JB et al. Nat Commun 2015 Nov 05;6:8827

PMID:29735745 - Control of mitotic chromosome condensation by the fission yeast transcription factor Zas1.

Schiklenk C et al. J Cell Biol 2018 Jul 02;217(7):2383-2401

PMID:26257282 - Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes.

Iwasaki O et al. Mol Cell 2015 Sep 03;59(5):755-67

PMID:21633354 - Condensin association with histone H2A shapes mitotic chromosomes.

Tada K et al. Nature 2011 Jun 01;474(7352):477-83

PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.

Skribbe M et al. Mol Cell 2025 Feb 19;

PMID:22645654 - Opposing role of condensin hinge against replication protein A in mitosis and interphase through promoting DNA annealing.

Akai Y et al. Open Biol 2011 Dec;1(4):110023

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

PMID:18362178 - Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis.

Nakazawa N et al. J Cell Biol 2008 Mar 24;180(6):1115-31

PMID:25764183 - Condensin HEAT subunits required for DNA repair, kinetochore/centromere function and ploidy maintenance in fission yeast.

Xu X et al. PLoS One 2015;10(3):e0119347

PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.

Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323

PMID:21540296 - Condensin phosphorylated by the Aurora-B-like kinase Ark1 is continuously required until telophase in a mode distinct from Top2.

Nakazawa N et al. J Cell Sci 2011 Jun 01;124(Pt 11):1795-807

PMID:31072933 - Suppressor screening reveals common kleisin-hinge interaction in condensin and cohesin, but different modes of regulation.

Xu X et al. Proc Natl Acad Sci U S A 2019 May 28;116(22):10889-10898

PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:20118936 - Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae.

Lantermann AB et al. Nat Struct Mol Biol 2010 Feb;17(2):251-7

PMID:24362309 - A genetic screen for functional partners of condensin in fission yeast.

Robellet X et al. G3 (Bethesda) 2014 Feb 19;4(2):373-81

PMID:27737959 - Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis.

Martin CA et al. Genes Dev 2016 Oct 01;30(19):2158-2172