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protein coding gene - sfc9 (SPBC8D2.07c) - transcription factor TFIIIC complex subunit Sfc9

Gene summary

Standard name
sfc9
Systematic ID
SPBC8D2.07c
Product
transcription factor TFIIIC complex subunit Sfc9
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
SPBC8D2.08c
UniProt ID
O13650
ORFeome ID
39/39F11
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome II: 1372488..1374966 reverse strand

Annotation

GO biological process

GO:0006338 - chromatin remodeling

References:

GO:0006383 - transcription by RNA polymerase III

References:

GO cellular component

GO:0005634 - nucleus

References:

GO:0000127 - transcription factor TFIIIC complex

References:

GO molecular function

GO:0000995 - RNA polymerase III general transcription initiation factor activity

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

Protein features

PBO:0111743 - zinc finger protein

Quantitative gene expression

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0000059 - abnormal mitotic cell cycle

References:

Genotypes:

FYPO:0003529 - inviable after spore germination, multiple cell divisions, cell cycle arrest in mitotic interphase, elongated cells

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0000070 - gene structure updated

Protein features

IDNameInterPro nameDB name
PF12657TFIIIC_deltaTFIIIC_delta_NPfam
PF12660zf-TFIIICTFIIIC_ZnfPfam
SSF50978WD40_repeat_dom_sfSUPERFAMILY
PTHR15496GTF3C4PANTHER

Orthologs

References / Literature

PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:26257282 - Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes.
Iwasaki O et al. Mol Cell 2015 Sep 03;59(5):755-67
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:23297348 - Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.
Chen JS et al. Mol Cell Proteomics 2013 May;12(5):1074-86
PMID:22540037 - Predicting the fission yeast protein interaction network.
Pancaldi V et al. G3 (Bethesda) 2012 Apr;2(4):453-67
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:30824696 - Systematic analysis reveals the prevalence and principles of bypassable gene essentiality.
Li J et al. Nat Commun 2019 Mar 01;10(1):1002
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
GO_REF:0000108 - Automatic assignment of GO terms using logical inference, based on on inter-ontology links.