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protein coding gene - tea1 (SPCC1223.06) - cell end marker Tea1

Gene summary

Standard name
tea1
Systematic ID
SPCC1223.06
Product
cell end marker Tea1
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
alp8
UniProt ID
P87061
ORFeome ID
48/48C11
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome III: 1848771..1852620 forward strand

Annotation

Comment

PBO:0036285 - localisation to cell tip microtubule-dependent

References:

GO biological process

GO:0061245 - establishment or maintenance of bipolar cell polarity

References:

GO:1990896 - protein localization to cell cortex of cell tip

References:

GO:0008360 - regulation of cell shape

References:

GO:0007165 - signal transduction

References:

GO cellular component

GO:0051285 - cell cortex of cell tip

References:

GO:0032153 - cell division site

References:

GO:0051286 - cell tip

References:

GO:0005881 - cytoplasmic microtubule

References:

GO:1904511 - cytoplasmic microtubule plus-end

References:

GO:0000935 - division septum

References:

GO:0035838 - growing cell tip

References:

GO:0015630 - microtubule cytoskeleton

References:

GO:1990752 - microtubule end

References:

GO:0035839 - non-growing cell tip

References:

GO:0035840 - old growing cell tip

References:

GO:0099070 - static microtubule bundle

References:

GO:0043332 - mating projection tip

References:

GO molecular function

GO:0005515 - protein binding

References:

GO:0043495 - protein-membrane adaptor activity

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

MOD:00047 - O-phospho-L-threonine

References:

MOD:00696 - phosphorylated residue

References:

Multi-locus phenotype

FYPO:0000190 - abnormal actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0001971 - abnormal cell separation after cytokinesis resulting in chained cells

References:

Genotypes:

FYPO:0000141 - abnormal mitotic sister chromatid segregation

References:

Genotypes:

FYPO:0000117 - abnormal septum assembly

References:

Genotypes:

FYPO:0001118 - abnormal vegetative cell morphology

References:

Genotypes:

FYPO:0001018 - abolished NETO

References:

Genotypes:

FYPO:0000930 - abolished protein localization to cell cortex during vegetative growth

References:

Genotypes:

FYPO:0006220 - abolished protein localization to septum

References:

Genotypes:

FYPO:0006027 - actin cables present in increased numbers

References:

Genotypes:

FYPO:0001394 - activation of monopolar cell growth at either end

References:

Genotypes:

FYPO:0003314 - activation of monopolar cell growth at new end

References:

Genotypes:

FYPO:0004700 - bent vegetative cell

References:

Genotypes:

FYPO:0001512 - branched, elongated cell

References:

Genotypes:

FYPO:0000082 - decreased cell population growth at high temperature

References:

Genotypes:

FYPO:0006637 - decreased protein localization to cell cortex of cell tip, with protein distributed in cortex

References:

Genotypes:

FYPO:0003317 - decreased protein localization to growing cell tip, with protein distributed in plasma membrane or cortex

References:

Genotypes:

FYPO:0001838 - decreased protein phosphorylation during vegetative growth

References:

Genotypes:

FYPO:0004085 - decreased vegetative cell growth

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0007380 - elongated T-shaped vegetative cell

References:

Genotypes:

FYPO:0004859 - increased cell wall polysaccharide level

References:

Genotypes:

FYPO:0003532 - increased monopolar index

References:

Genotypes:

FYPO:0002302 - inviable after spore germination, multiple cell divisions, spheroid cell

References:

Genotypes:

FYPO:0002411 - inviable curved elongated vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0000228 - lagging mitotic chromosomes

References:

Genotypes:

FYPO:0005880 - long interphase microtubules curved around cell end

References:

Genotypes:

FYPO:0001019 - monopolar actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0000118 - multiseptate vegetative cell

References:

Genotypes:

FYPO:0001294 - normal actin cortical patch localization

References:

Genotypes:

FYPO:0005465 - normal cell polarity

References:

Genotypes:

FYPO:0001399 - normal mitotic spindle

References:

Genotypes:

FYPO:0007451 - normal protein localization to cell cortex of cell tip during vegetative growth

References:

Genotypes:

FYPO:0003316 - normal protein localization to growing cell tip

References:

Genotypes:

FYPO:0002085 - normal vegetative cell growth

References:

Genotypes:

FYPO:0001315 - normal vegetative cell morphology

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0001017 - premature NETO

References:

Genotypes:

FYPO:0000091 - sensitive to thiabendazole

References:

Genotypes:

FYPO:0000021 - spheroid vegetative cell

References:

Genotypes:

FYPO:0002942 - swollen spheroid cell during G0

References:

Genotypes:

FYPO:0000945 - swollen spheroid vegetative cell

References:

Genotypes:

FYPO:0007379 - T-shaped vegetative cell

References:

Genotypes:

FYPO:0000013 - T-shaped vegetative cell with normal cell length

References:

Genotypes:

FYPO:0002459 - viable branched, elongated vegetative cell

References:

Genotypes:

FYPO:0002112 - viable curved vegetative cell

References:

Genotypes:

FYPO:0001496 - viable elongated multiseptate vegetative cell

References:

Genotypes:

FYPO:0003481 - viable elongated vegetative cell, elongated upon mitotic entry

References:

Genotypes:

FYPO:0000648 - viable small vegetative cell

References:

Genotypes:

FYPO:0006822 - viable small vegetative cell with normal cell growth rate

References:

Genotypes:

FYPO:0004103 - viable spherical vegetative cell

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0002104 - viable vegetative cell with normal cell shape

References:

Genotypes:

Protein features

PBO:0111882 - kelch repeat protein

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002373 - abnormal actin cortical patch localization during mitosis

References:

Genotypes:

FYPO:0000190 - abnormal actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0000240 - abnormal filament morphology

References:

Genotypes:

FYPO:0005464 - abnormal maintenance of protein location at cell tip during vegetative growth

References:

Genotypes:

FYPO:0003625 - abnormal microtubule cytoskeleton morphology during mitotic interphase

References:

Genotypes:

FYPO:0000147 - abnormal NETO

References:

Genotypes:

FYPO:0006547 - abnormal plasma membrane phosphatidylserine distribution resulting in decreased concentration at cell tip

References:

Genotypes:

FYPO:0005503 - abnormally monopolar protein localization to cell tip

References:

Genotypes:

FYPO:0001018 - abolished NETO

References:

Genotypes:

FYPO:0000930 - abolished protein localization to cell cortex during vegetative growth

References:

Genotypes:

FYPO:0006502 - abolished protein localization to cell cortex of cell tip during vegetative growth

References:

Genotypes:

FYPO:0003329 - abolished protein localization to cell tip during mitotic interphase

References:

Genotypes:

FYPO:0003209 - abolished protein localization to cell tip, with protein mislocalized to cytoplasm

References:

Genotypes:

FYPO:0002859 - abolished protein localization to non-growing cell tip

References:

Genotypes:

FYPO:0007995 - abolished protein localization to old cell tip during mitotic interphase

References:

Genotypes:

FYPO:0000705 - abolished protein-protein interaction

References:

Genotypes:

FYPO:0001394 - activation of monopolar cell growth at either end

References:

Genotypes:

FYPO:0003314 - activation of monopolar cell growth at new end

References:

Genotypes:

FYPO:0008389 - activation of monopolar cell growth at old end during septation

References:

Genotypes:

FYPO:0004700 - bent vegetative cell

References:

Genotypes:

FYPO:0007563 - cell cycle arrest in mitotic G1 phase in response to pheromone without starvation

References:

Genotypes:

FYPO:0002924 - decreased cell population growth on maltose carbon source

References:

Genotypes:

FYPO:0001176 - decreased cell population growth on sucrose carbon source

References:

Genotypes:

FYPO:0003150 - decreased NETO

References:

Genotypes:

FYPO:0005798 - decreased protein localization to cell cortex of cell tip during vegetative growth

References:

Genotypes:

FYPO:0006637 - decreased protein localization to cell cortex of cell tip, with protein distributed in cortex

References:

Genotypes:

FYPO:0001586 - decreased protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0002871 - decreased protein localization to growing cell tip

References:

Genotypes:

FYPO:0002556 - decreased protein localization to medial cortex, with protein distributed in cell cortex near non-growing end, during vegetative growth

References:

Genotypes:

FYPO:0002679 - decreased protein phosphorylation

References:

Genotypes:

FYPO:0001645 - decreased protein-protein interaction

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0004806 - incomplete cell wall disassembly at cell fusion site

References:

Genotypes:

FYPO:0003938 - increased cell population growth during glucose starvation

References:

Genotypes:

FYPO:0005261 - increased cell population growth on galactose carbon source

References:

Genotypes:

FYPO:0009101 - increased cell population growth on glycerol and galactose carbon source

References:

Genotypes:

FYPO:0004167 - increased cell population growth on glycerol carbon source

References:

Genotypes:

FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

References:

Genotypes:

FYPO:0009093 - increased cell population growth on lysine and serine nitrogen source

References:

Genotypes:

FYPO:0009028 - increased cell population growth on proline nitrogen source

References:

Genotypes:

FYPO:0009074 - increased cell population growth on serine nitrogen source

References:

Genotypes:

FYPO:0009096 - increased cell population growth on xylose carbon source

References:

Genotypes:

FYPO:0003532 - increased monopolar index

References:

Genotypes:

FYPO:0006874 - increased protein localization to cell cortex of old growing cell tip

References:

Genotypes:

FYPO:0001677 - increased protein localization to medial cortex during vegetative growth

References:

Genotypes:

FYPO:0002870 - increased protein localization to non-growing cell tip

References:

Genotypes:

FYPO:0004557 - increased vegetative cell population growth

References:

Genotypes:

FYPO:0004511 - long curved interphase microtubules

References:

Genotypes:

FYPO:0004611 - long interphase microtubules

References:

Genotypes:

FYPO:0005880 - long interphase microtubules curved around cell end

References:

Genotypes:

FYPO:0006636 - mislocalized protein distributed in cell cortex

References:

Genotypes:

FYPO:0007388 - misoriented mitotic spindle

References:

Genotypes:

FYPO:0001390 - misoriented septum during vegetative growth

References:

Genotypes:

FYPO:0001019 - monopolar actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0007997 - monopolar actin cortical patch localization to new end

References:

Genotypes:

FYPO:0000674 - normal cell population growth at high temperature

References:

Genotypes:

FYPO:0003797 - normal conjugation frequency

References:

Genotypes:

FYPO:0007810 - normal cytoplasmic microtubules during cellular response to pheromone

References:

Genotypes:

FYPO:0000964 - normal growth on thiabendazole

References:

Genotypes:

FYPO:0003702 - normal microtubule cytoskeleton morphology during vegetative growth

References:

Genotypes:

FYPO:0007412 - normal mitotic spindle orientation

References:

Genotypes:

FYPO:0002559 - normal protein localization to actomyosin contractile ring

References:

Genotypes:

FYPO:0002442 - normal protein localization to cell division site

References:

Genotypes:

FYPO:0001587 - normal protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0003316 - normal protein localization to growing cell tip

References:

Genotypes:

FYPO:0004731 - normal protein localization to interphase microtubule plus-end

References:

Genotypes:

FYPO:0003185 - normal protein localization to microtubule cytoskeleton during mitotic interphase

References:

Genotypes:

FYPO:0008003 - normal protein localization to site of mechanical stress

References:

Genotypes:

FYPO:0005827 - normal protein transport along microtubule during vegetative growth

References:

Genotypes:

FYPO:0000703 - normal protein-protein interaction

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0006501 - premature actin fusion focus assembly

References:

Genotypes:

FYPO:0003527 - protein mislocalized to cell tip

References:

Genotypes:

FYPO:0000067 - resistance to brefeldin A

References:

Genotypes:

FYPO:0000763 - resistance to cadmium

References:

Genotypes:

FYPO:0002693 - resistance to diamide

References:

Genotypes:

FYPO:0009038 - resistance to egtazic acid

References:

Genotypes:

FYPO:0001453 - resistance to ethanol

References:

Genotypes:

FYPO:0009083 - resistance to lithium chloride and methyl methanesulfonate

References:

Genotypes:

FYPO:0009081 - resistance to potassium chloride and methyl methanesulfonate

References:

Genotypes:

FYPO:0003383 - resistance to tert-butyl hydroperoxide

References:

Genotypes:

FYPO:0000327 - resistance to trichostatin A

References:

Genotypes:

FYPO:0001034 - resistance to tunicamycin

References:

Genotypes:

FYPO:0003595 - S-shaped cell

References:

Genotypes:

FYPO:0004325 - sensitive to 5-fluorouracil

References:

Genotypes:

FYPO:0007868 - sensitive to actin polymerization inhibitor

References:

Genotypes:

FYPO:0001097 - sensitive to amitrole

References:

Genotypes:

FYPO:0009067 - sensitive to amorolfine

References:

Genotypes:

FYPO:0007921 - sensitive to benzamidine

References:

Genotypes:

FYPO:0000095 - sensitive to bleomycin

References:

Genotypes:

FYPO:0000842 - sensitive to ethanol during vegetative growth

References:

Genotypes:

FYPO:0007928 - sensitive to ethylenediaminetetraacetic acid

References:

Genotypes:

FYPO:0000785 - sensitive to formamide

References:

Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

References:

Genotypes:

FYPO:0001719 - sensitive to lithium

References:

Genotypes:

FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0001214 - sensitive to potassium chloride

References:

Genotypes:

FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0005889 - sensitive to sodium chloride

References:

Genotypes:

FYPO:0009090 - sensitive to sodium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0002328 - sensitive to terbinafine

References:

Genotypes:

FYPO:0006103 - short interphase microtubules

References:

Genotypes:

FYPO:0002848 - T-shaped cell during recovery from stationary phase

References:

Genotypes:

FYPO:0007379 - T-shaped vegetative cell

References:

Genotypes:

FYPO:0000013 - T-shaped vegetative cell with normal cell length

References:

Genotypes:

FYPO:0002215 - viable curved elongated vegetative cell

References:

Genotypes:

FYPO:0002112 - viable curved vegetative cell

References:

Genotypes:

FYPO:0003481 - viable elongated vegetative cell, elongated upon mitotic entry

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0002197 - viable vegetative cell with abnormal cell shape

References:

Genotypes:

FYPO:0002177 - viable vegetative cell with normal cell morphology

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

Protein features

IDNameInterPro nameDB name
PF01344Kelch_1Kelch_1PFAM
PF24681Kelch_KLHDC2_KLHL20_DRC7PFAM
SM00612kelc_smartKelch_1SMART
G3DSA:2.120.10.80:FF:000049FUNFAM
SSF117281Kelch motifKelch-typ_b-propellerSUPERFAMILY
G3DSA:2.120.10.80Kelch-typ_b-propellerGENE3D
PTHR46093ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5PANTHER
CoilCoilCOILS
mobidb-lite-Disorderdisorder_predictionMOBIDB-Disorder
mobidb-lite-Low-complexitydisorder_predictionMOBIDB-Low-complexity
mobidb-lite-Polardisorder_predictionMOBIDB-Polar
mobidb-lite-Positive-Polyelectrolytedisorder_predictionMOBIDB-Positive-Polyelectrolyte

Orthologs

References / Literature

PMID:14663827 - Role of Tea1p, Tea3p and Pom1p in the determination of cell ends in Schizosaccharomyces pombe.
Niccoli T et al. Yeast 2003 Dec;20(16):1349-58
PMID:12764130 - The kelch repeat protein, Tea1, is a potential substrate target of the p21-activated kinase, Shk1, in the fission yeast, Schizosaccharomyces pombe.
Kim H et al. J Biol Chem 2003 Aug 08;278(32):30074-82
PMID:21703453 - A phosphorylation cycle shapes gradients of the DYRK family kinase Pom1 at the plasma membrane.
Hachet O et al. Cell 2011 Jun 24;145(7):1116-28
PMID:16611237 - Modulation of Alp4 function in Schizosaccharomyces pombe induces novel phenotypes that imply distinct functions for nuclear and cytoplasmic gamma-tubulin complexes.
Masuda H et al. Genes Cells 2006 Apr;11(4):319-36
PMID:16988828 - Spatial regulation of cytokinesis by the Kin1 and Pom1 kinases in fission yeast.
La Carbona S et al. Curr Genet 2006 Dec;50(6):377-91
PMID:27180904 - Sterol-Rich Membrane Domains Define Fission Yeast Cell Polarity.
Makushok T et al. Cell 2016 May 19;165(5):1182-1196
PMID:27298342 - Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks.
Willis NA et al. Proc Natl Acad Sci U S A 2016 Jun 28;113(26):E3676-85
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:11018050 - Tea2p is a kinesin-like protein required to generate polarized growth in fission yeast.
Browning H et al. J Cell Biol 2000 Oct 02;151(1):15-28
PMID:25837586 - Spontaneous Cdc42 polarization independent of GDI-mediated extraction and actin-based trafficking.
Bendezú FO et al. PLoS Biol 2015 Apr;13(4):e1002097
PMID:11972773 - The p21-activated kinase, Shk1, is required for proper regulation of microtubule dynamics in the fission yeast, Schizosaccharomyces pombe.
Qyang Y et al. Mol Microbiol 2002 Apr;44(2):325-34
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.
Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:28357272 - A central role for TOR signalling in a yeast model for juvenile CLN3 disease.
Bond ME et al. Microb Cell 2015 Nov 11;2(12):466-480
PMID:27852900 - Gradients of phosphatidylserine contribute to plasma membrane charge localization and cell polarity in fission yeast.
Haupt A et al. Mol Biol Cell 2017 Jan 01;28(1):210-220
PMID:22137473 - Shaping fission yeast cells by rerouting actin-based transport on microtubules.
Lo Presti L et al. Curr Biol 2011 Dec 20;21(24):2064-9
PMID:22696680 - Fission yeast Alp14 is a dose-dependent plus end-tracking microtubule polymerase.
Al-Bassam J et al. Mol Biol Cell 2012 Aug;23(15):2878-90
PMID:29930085 - Local and global Cdc42 guanine nucleotide exchange factors for fission yeast cell polarity are coordinated by microtubules and the Tea1-Tea4-Pom1 axis.
Tay YD et al. J Cell Sci 2018 Jul 19;131(14)
PMID:31822915 - Mkt1 is required for RNAi-mediated silencing and establishment of heterochromatin in fission yeast.
Taglini F et al. Nucleic Acids Res 2020 Feb 20;48(3):1239-1253
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23615447 - Compartmentalized nodes control mitotic entry signaling in fission yeast.
Deng L et al. Mol Biol Cell 2013 Jun;24(12):1872-81
PMID:25373780 - A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.
Graml V et al. Dev Cell 2014 Oct 27;31(2):227-239
PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.
Skribbe M et al. Mol Cell 2025 Feb 19;
PMID:9405296 - Genes that cause aberrant cell morphology by overexpression in fission yeast: a role of a small GTP-binding protein Rho2 in cell morphogenesis.
Hirata D et al. J Cell Sci 1998 Jan;111 ( Pt 2):149-59
PMID:9573052 - Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis.
Bähler J et al. Genes Dev 1998 May 01;12(9):1356-70
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:11950884 - Different mechanisms of cell polarisation in vegetative and shmooing growth in fission yeast.
Niccoli T et al. J Cell Sci 2002 Apr 15;115(Pt 8):1651-62
PMID:39156640 - Fission yeast Bgs1 glucan synthase participates in the control of growth polarity and membrane traffic.
Ramos M et al. iScience 2024 Aug 16;27(8):110477
PMID:21652630 - Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.
Snaith HA et al. J Cell Sci 2011 Jul 01;124(Pt 13):2187-99
PMID:11516644 - Role of bud6p and tea1p in the interaction between actin and microtubules for the establishment of cell polarity in fission yeast.
Glynn JM et al. Curr Biol 2001 Jun 05;11(11):836-45
PMID:15837798 - Efficient formation of bipolar microtubule bundles requires microtubule-bound gamma-tubulin complexes.
Janson ME et al. J Cell Biol 2005 Apr 25;169(2):297-308
PMID:12052869 - Two ras pathways in fission yeast are differentially regulated by two ras guanine nucleotide exchange factors.
Papadaki P et al. Mol Cell Biol 2002 Jul;22(13):4598-606
PMID:8522609 - Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle.
Verde F et al. J Cell Biol 1995 Dec;131(6 Pt 1):1529-38
PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.
Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:19542312 - Functional genomics of adhesion, invasion, and mycelial formation in Schizosaccharomyces pombe.
Dodgson J et al. Eukaryot Cell 2009 Aug;8(8):1298-306
PMID:39476757 - Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.
Cipak L et al. Biochem Biophys Res Commun 2024 Oct 25;736:150895
PMID:23695164 - Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.
Das J et al. Sci Signal 2013 May 21;6(276):ra38
PMID:26124291 - A stable microtubule array drives fission yeast polarity reestablishment upon quiescence exit.
Laporte D et al. J Cell Biol 2015 Jul 06;210(1):99-113
PMID:12007420 - Tea3p is a cell end marker activating polarized growth in Schizosaccharomyces pombe.
Arellano M et al. Curr Biol 2002 Apr 30;12(9):751-6
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:10503548 - Analysis of the cps1 gene provides evidence for a septation checkpoint in Schizosaccharomyces pombe.
Le Goff X et al. Mol Gen Genet 1999 Aug;262(1):163-72
PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323
PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.
Halova L et al. Open Biol 2021 Apr;11(4):200405
PMID:12034771 - Roles of fission yeast tea1p in the localization of polarity factors and in organizing the microtubular cytoskeleton.
Behrens R et al. J Cell Biol 2002 May 27;157(5):783-93
PMID:14506270 - The novel Rho GTPase-activating protein family protein, Rga8, provides a potential link between Cdc42/p21-activated kinase and Rho signaling pathways in the fission yeast, Schizosaccharomyces pombe.
Yang P et al. J Biol Chem 2003 Dec 05;278(49):48821-30
PMID:18328707 - Pom1 DYRK regulates localization of the Rga4 GAP to ensure bipolar activation of Cdc42 in fission yeast.
Tatebe H et al. Curr Biol 2008 Mar 11;18(5):322-30
PMID:18931302 - Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes.
Dixon SJ et al. Proc Natl Acad Sci U S A 2008 Oct 28;105(43):16653-8
PMID:15936270 - Wsh3/Tea4 is a novel cell-end factor essential for bipolar distribution of Tea1 and protects cell polarity under environmental stress in S. pombe.
Tatebe H et al. Curr Biol 2005 Jun 07;15(11):1006-15
PMID:15827087 - End4/Sla2 is involved in establishment of a new growth zone in Schizosaccharomyces pombe.
Castagnetti S et al. J Cell Sci 2005 May 01;118(Pt 9):1843-50
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:16951255 - S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner.
Grallert A et al. Genes Dev 2006 Sep 01;20(17):2421-36
PMID:24554432 - The Tea4-PP1 landmark promotes local growth by dual Cdc42 GEF recruitment and GAP exclusion.
Kokkoris K et al. J Cell Sci 2014 May 01;127(Pt 9):2005-16
PMID:29689193 - Mechanosensation Dynamically Coordinates Polar Growth and Cell Wall Assembly to Promote Cell Survival.
Davì V et al. Dev Cell 2018 Apr 23;45(2):170-182.e7
PMID:12789340 - Fission yeast mod5p regulates polarized growth through anchoring of tea1p at cell tips.
Snaith HA et al. Nature 2003 Jun 05;423(6940):647-51
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
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PMID:14596912 - The protein kinase kin1, the fission yeast orthologue of mammalian MARK/PAR-1, localises to new cell ends after mitosis and is important for bipolar growth.
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