PomBase home

protein coding gene - rml2 (SPCC16C4.15) - mitochondrial ribosomal protein subunit L2

Gene summary

Standard name
rml2
Systematic ID
SPCC16C4.15
Product
mitochondrial ribosomal protein subunit L2
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
Q9Y7P4
ORFeome ID
15/15E12
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome III: 695912..697482 forward strand

Annotation

GO biological process

GO:0032543 - mitochondrial translation

References:

GO cellular component

GO:0005762 - mitochondrial large ribosomal subunit

References:

GO molecular function

GO:0003723 - RNA binding

References:

GO:0003735 - structural constituent of ribosome

References:

Protein sequence feature

SO:0001808 - mitochondrial_targeting_signal

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0002199 - inviable vegetative cell with normal cell morphology

References:

Genotypes:

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0000070 - gene structure updated

References:

Protein features

IDNameInterPro nameDB name
PF00181Ribosomal_L2_NRibosomal_uL2_RNA-bd_domPfam
PF03947Ribosomal_L2_CRibosomal_uL2_CPfam
PS00467RIBOSOMAL_L2Ribosomal_uL2_CSPROSITE patterns
SM01382Ribosomal_L2_CRibosomal_uL2_CSMART
SM01383Ribosomal_L2Ribosomal_uL2_RNA-bd_domSMART
G3DSA:2.30.30.30:FF:000001CATH-FunFam
G3DSA:2.40.50.140:FF:000128CATH-FunFam
G3DSA:4.10.950.10:FF:000001CATH-FunFam
G3DSA:2.30.30.30Rib_uL2_dom2CATH-Gene3D
G3DSA:2.40.50.140NA-bd_OB-foldCATH-Gene3D
G3DSA:4.10.950.10Ribosomal_uL2_dom3CATH-Gene3D
SSF50104Translation_prot_SH3-like_sfSUPERFAMILY
SSF50249NA-bd_OB-foldSUPERFAMILY
PTHR13691Ribosomal_uL2PANTHER
TIGR01171rplB_bactRibosomal_uL2_bact_orgNCBIFAM
mobidb-lite-Disorderdisorder_predictionMobiDB-Disorder
mobidb-lite-Polyampholytedisorder_predictionMobiDB-Polyampholyte

Orthologs

References / Literature

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:30321377 - Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome.
Telekawa C et al. Nucleic Acids Res 2018 Nov 30;46(21):11169-11183
PMID:24818994 - The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2.
Jongjitwimol J et al. PLoS One 2014;9(5):e94182
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.
UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83