protein coding gene - rsa4 (SPCC18.05c) - notchless-like ribosome biogenesis protein Rsa4

Gene summary

Standard name

rsa4

Systematic ID

SPCC18.05c

Product

notchless-like ribosome biogenesis protein Rsa4

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

O74855

ORFeome ID

34/34H09

Characterisation status

biological role inferred

Feature type

mRNA gene

Genomic location

chromosome III: 1962945..1964815 reverse strand

Annotation

Protein features

Orthologs

• NLE1 (HGNC:19889) Homo sapiens
• rsa4 (SJAG_02754) Schizosaccharomyces japonicus
• RSA4 (YCR072C) Saccharomyces cerevisiae

References / Literature

PMID:27667686 - Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis.

Kawashima SA et al. Cell 2016 Oct 06;167(2):512-524.e14

PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.

Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:24013502 - Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Wang J et al. Genes Dev 2013 Sep 01;27(17):1886-902

PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.

Skribbe M et al. Mol Cell 2025 Feb 19;

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:25375137 - Systematic analysis of the role of RNA-binding proteins in the regulation of RNA stability.

Hasan A et al. PLoS Genet 2014 Nov;10(11):e1004684

PMID:30099677 - Genome-wide evidences of bisphenol a toxicity using Schizosaccharomyces pombe.

Kim DM et al. Arch Pharm Res 2018 Aug;41(8):830-837

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

PMID:21436456 - Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA.

Zhang K et al. Science 2011 Mar 25;331(6024):1624-7

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

GO_REF:0000033 - Annotation inferences using phylogenetic trees