protein coding gene - inv1 (SPCC191.11) - external invertase, beta-fructofuranosidase Inv1

Gene summary

Standard name

inv1

Systematic ID

SPCC191.11

Product

external invertase, beta-fructofuranosidase Inv1

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

O59852

ORFeome ID

45/45G05

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome III: 1723434..1726164 forward strand

Annotation

Protein features

Orthologs

• inv1 (SJAG_04301) Schizosaccharomyces japonicus
• SUC2 (YIL162W) Saccharomyces cerevisiae

References / Literature

GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.

PMID:22416758 - Mpg2 interacts and cooperates with Mpg1 to maintain yeast glycosylation.

Muñoz-Centeno MC et al. FEMS Yeast Res 2012 Aug;12(5):511-20

PMID:34460892 - Transcriptome sequencing and screening of genes related to glucose availability in Schizosaccharomyces pombe by RNA-seq analysis.

Tarhan Ç et al. Genet Mol Biol 2021;44(3):e20200245

PMID:11136464 - Functional characterization of the alpha-glucoside transporter Sut1p from Schizosaccharomyces pombe, the first fungal homologue of plant sucrose transporters.

Reinders A et al. Mol Microbiol 2001 Jan;39(2):445-54

PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704

PMID:28410370 - A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Dudin O et al. PLoS Genet 2017 Apr;13(4):e1006721

PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.

Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399

PMID:16049679 - Mpg1, a fission yeast protein required for proper septum structure, is involved in cell cycle progression through cell-size checkpoint.

Donoso I et al. Mol Genet Genomics 2005 Sep;274(2):155-67

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:33536395 - The fission yeast gmn2 + gene encodes an ERD1 homologue of Saccharomyces cerevisiae required for protein glycosylation and retention of luminal endoplasmic reticulum proteins.

Tanaka N et al. J Gen Appl Microbiol 2021 Jun 03;67(2):67-76

PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.

Rodríguez-López M et al. Elife 2023 Oct 03;12

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:25375137 - Systematic analysis of the role of RNA-binding proteins in the regulation of RNA stability.

Hasan A et al. PLoS Genet 2014 Nov;10(11):e1004684

PMID:26896847 - Ensembl comparative genomics resources.

Herrero J et al. Database (Oxford) 2016;2016

PMID:19620394 - Distinctive responses to nitrogen starvation in the dominant active mutants of the fission yeast Rheb GTPase.

Murai T et al. Genetics 2009 Oct;183(2):517-27

PMID:31626996 - Multiplexed proteome profiling of carbon source perturbations in two yeast species with SL-SP3-TMT.

Paulo JA et al. J Proteomics 2020 Jan 06;210:103531

PMID:29432178 - General amino acid control in fission yeast is regulated by a nonconserved transcription factor, with functions analogous to Gcn4/Atf4.

Duncan CDS et al. Proc Natl Acad Sci U S A 2018 Feb 20;115(8):E1829-E1838

GO_REF:0000033 - Annotation inferences using phylogenetic trees

PMID:22140232 - Snf1-like protein kinase Ssp2 regulates glucose derepression in Schizosaccharomyces pombe.

Matsuzawa T et al. Eukaryot Cell 2012 Feb;11(2):159-67

PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.

Skribbe M et al. Mol Cell 2025 Feb 19;

PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.

Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105

PMID:2112088 - The ryh1 gene in the fission yeast Schizosaccharomyces pombe encoding a GTP-binding protein related to ras, rho and ypt: structure, expression and identification of its human homologue.

Hengst L et al. EMBO J 1990 Jun;9(6):1949-55

PMID:9535817 - Isolation and characterization of an invertase and its repressor genes from Schizosaccharomyces pombe.

Tanaka N et al. Biochem Biophys Res Commun 1998 Apr 07;245(1):246-53

PMID:21504829 - Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Stewart EV et al. Mol Cell 2011 Apr 22;42(2):160-71

PMID:2187435 - Purification and characterization of the invertase from Schizosaccharomyces pombe. A comparative analysis with the invertase from Saccharomyces cerevisiae.

Moreno S et al. Biochem J 1990 May 01;267(3):697-702

PMID:20622008 - A chromatin-remodeling protein is a component of fission yeast mediator.

Khorosjutina O et al. J Biol Chem 2010 Sep 24;285(39):29729-37

PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.

Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963

PMID:36478272 - Translation-complex profiling of fission yeast cells reveals dynamic rearrangements of scanning ribosomal subunits upon nutritional stress.

Duncan CDS et al. Nucleic Acids Res 2022 Dec 09;50(22):13011-13025

PMID:27481777 - Identification of nuclear genes affecting 2-Deoxyglucose resistance in Schizosaccharomyces pombe.

Vishwanatha A et al. FEMS Yeast Res 2016 Sep;16(6)

PMID:16624901 - A defect in protein farnesylation suppresses a loss of Schizosaccharomyces pombe tsc2+, a homolog of the human gene predisposing to tuberous sclerosis complex.

Nakase Y et al. Genetics 2006 Jun;173(2):569-78

PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.

UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531