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protein coding gene - myo52 (SPCC1919.10c) - myosin type V

Gene summary

Standard name
myo52
Systematic ID
SPCC1919.10c
Product
myosin type V
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
myo4
UniProt ID
O94477
ORFeome ID
31/31A01
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome III: 2224882..2229940 reverse strand

Annotation

Disease association

MONDO:0030810 - cholestasis, progressive familial intrahepatic, 10

References:

MONDO:0008962 - Griscelli syndrome type 1

References:

MONDO:0009635 - microvillus inclusion disease

References:

GO biological process

GO:0061572 - actin filament bundle organization

References:

GO:0061573 - actin filament bundle retrograde transport

References:

GO:0006897 - endocytosis

References:

GO:0070649 - formin-nucleated actin cable assembly

References:

GO:1904600 - mating projection actin fusion focus assembly

References:

GO:1990896 - protein localization to cell cortex of cell tip

References:

GO:1904601 - protein transport to mating projection actin fusion focus

References:

GO:0097576 - vacuole fusion

References:

GO:0030050 - vesicle transport along actin filament

References:

GO cellular component

GO:0030479 - actin cortical patch

References:

GO:0051285 - cell cortex of cell tip

References:

GO:1902716 - cell cortex of growing cell tip

References:

GO:0032153 - cell division site

References:

GO:0051286 - cell tip

References:

GO:0090726 - cortical dynamic polarity patch

References:

GO:0097575 - lateral cell cortex

References:

GO:1990819 - mating projection actin fusion focus

References:

GO:0031097 - medial cortex

References:

GO:0016020 - membrane

References:

GO:0031475 - myosin V complex

References:

GO molecular function

GO:0051015 - actin filament binding

References:

GO:0005524 - ATP binding

References:

GO:0016887 - ATP hydrolysis activity

References:

GO:0000146 - microfilament motor activity

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

MOD:00047 - O-phospho-L-threonine

References:

MOD:00048 - O4'-phospho-L-tyrosine

References:

MOD:00696 - phosphorylated residue

References:

Multi-locus phenotype

FYPO:0002872 - abnormal endoplasmic reticulum localization

References:

Genotypes:

FYPO:0006497 - abnormal plasma membrane phosphatidylserine distribution

References:

Genotypes:

FYPO:0004802 - abnormal protein localization to shmoo tip

References:

Genotypes:

FYPO:0000117 - abnormal septum assembly

References:

Genotypes:

FYPO:0000026 - abnormal vegetative cell polarity

References:

Genotypes:

FYPO:0000413 - abolished cell fusion during mating

References:

Genotypes:

FYPO:0001585 - abolished protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0002482 - inviable spheroid vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0002401 - microtubule bundles present in increased numbers

References:

Genotypes:

FYPO:0007689 - normal cell growth polarization

References:

Genotypes:

FYPO:0007114 - normal microtubule bundle

References:

Genotypes:

FYPO:0001587 - normal protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0001945 - normal protein secretion

References:

Genotypes:

FYPO:0006386 - protein abnormally dispersed at shmoo tip

References:

Genotypes:

FYPO:0007393 - septum mislocalized to cell tip

References:

Genotypes:

FYPO:0006821 - slow vegetative cell growth

References:

Genotypes:

FYPO:0000021 - spheroid vegetative cell

References:

Genotypes:

FYPO:0000024 - stubby vegetative cell

References:

Genotypes:

FYPO:0002380 - viable spheroid vegetative cell

References:

Genotypes:

FYPO:0007231 - viable spindle-shaped cell

References:

Genotypes:

FYPO:0002106 - viable stubby vegetative cell

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

Protein features

PBO:0111829 - IQ domain

Qualitative gene expression

PomGeneEx:0000018 - protein level increased

References:

PomGeneEx:0000011 - RNA level increased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002030 - abnormal actin cable organization

References:

Genotypes:

FYPO:0000801 - abnormal actin cytoskeleton organization during vegetative growth

References:

Genotypes:

FYPO:0002089 - abnormal exocytosis during vegetative growth

References:

Genotypes:

FYPO:0001370 - abnormal protein localization

References:

Genotypes:

FYPO:0000443 - abnormal protein localization during vegetative growth

References:

Genotypes:

FYPO:0004802 - abnormal protein localization to shmoo tip

References:

Genotypes:

FYPO:0004481 - abolished cell population growth at high temperature

References:

Genotypes:

FYPO:0001880 - abolished protein localization to cell division site

References:

Genotypes:

FYPO:0001585 - abolished protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0003209 - abolished protein localization to cell tip, with protein mislocalized to cytoplasm

References:

Genotypes:

FYPO:0001512 - branched, elongated cell

References:

Genotypes:

FYPO:0000082 - decreased cell population growth at high temperature

References:

Genotypes:

FYPO:0000080 - decreased cell population growth at low temperature

References:

Genotypes:

FYPO:0009075 - decreased cell population growth on fructose carbon source

References:

Genotypes:

FYPO:0001407 - decreased cell population growth on glucose carbon source

References:

Genotypes:

FYPO:0000684 - decreased cell population growth on glycerol carbon source

References:

Genotypes:

FYPO:0001176 - decreased cell population growth on sucrose carbon source

References:

Genotypes:

FYPO:0001324 - decreased protein level during vegetative growth

References:

Genotypes:

FYPO:0002699 - decreased protein localization to actomyosin contractile ring

References:

Genotypes:

FYPO:0002869 - decreased protein localization to cell division site

References:

Genotypes:

FYPO:0001586 - decreased protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0006589 - decreased protein localization to shmoo tip membrane, with protein distributed in plasma membrane

References:

Genotypes:

FYPO:0000538 - decreased protein secretion during vegetative growth

References:

Genotypes:

FYPO:0002441 - decreased rate of actin cable retrograde transport

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0000729 - delayed onset of actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0002021 - dispersed actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0001122 - elongated vegetative cell

References:

Genotypes:

FYPO:0002086 - exocytic vesicles present in increased numbers

References:

Genotypes:

FYPO:0004806 - incomplete cell wall disassembly at cell fusion site

References:

Genotypes:

FYPO:0009077 - increased cell population growth on ethanol carbon source

References:

Genotypes:

FYPO:0005261 - increased cell population growth on galactose carbon source

References:

Genotypes:

FYPO:0009052 - increased cell population growth on glutamate nitrogen source

References:

Genotypes:

FYPO:0009101 - increased cell population growth on glycerol and galactose carbon source

References:

Genotypes:

FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

References:

Genotypes:

FYPO:0009072 - increased cell population growth on lysine nitrogen source

References:

Genotypes:

FYPO:0005262 - increased cell population growth on maltose carbon source

References:

Genotypes:

FYPO:0009098 - increased cell population growth on mannitol carbon source

References:

Genotypes:

FYPO:0009096 - increased cell population growth on xylose carbon source

References:

Genotypes:

FYPO:0005543 - increased duration of actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0003482 - increased punctate cytoplasmic protein localization

References:

Genotypes:

FYPO:0000650 - increased septation index

References:

Genotypes:

FYPO:0004557 - increased vegetative cell population growth

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0002444 - loss of punctate cytoplasmic protein localization

References:

Genotypes:

FYPO:0000245 - loss of viability in stationary phase

References:

Genotypes:

FYPO:0004097 - normal actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0005465 - normal cell polarity

References:

Genotypes:

FYPO:0000426 - normal endocytosis

References:

Genotypes:

FYPO:0000644 - normal protein localization during vegetative growth

References:

Genotypes:

FYPO:0002442 - normal protein localization to cell division site

References:

Genotypes:

FYPO:0001587 - normal protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0008003 - normal protein localization to site of mechanical stress

References:

Genotypes:

FYPO:0004895 - normal rate of actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0001120 - pear-shaped vegetative cell

References:

Genotypes:

FYPO:0009031 - resistance to bleomycin

References:

Genotypes:

FYPO:0009032 - resistance to bortezomib

References:

Genotypes:

FYPO:0000073 - resistance to caffeine

References:

Genotypes:

FYPO:0009068 - resistance to ciclopirox olamine

References:

Genotypes:

FYPO:0009034 - resistance to ethylenediaminetetraacetic acid

References:

Genotypes:

FYPO:0001103 - resistance to hydrogen peroxide

References:

Genotypes:

FYPO:0001583 - resistance to lithium

References:

Genotypes:

FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0000725 - resistance to methyl methanesulfonate

References:

Genotypes:

FYPO:0009081 - resistance to potassium chloride and methyl methanesulfonate

References:

Genotypes:

FYPO:0000077 - resistance to rapamycin

References:

Genotypes:

FYPO:0009040 - resistance to tea tree oil

References:

Genotypes:

FYPO:0000830 - resistance to vanadate

References:

Genotypes:

FYPO:0009065 - resistance to X-rays and rapamycin during vegetative growth

References:

Genotypes:

FYPO:0007933 - sensitive to 2,2′-dipyridyl

References:

Genotypes:

FYPO:0004325 - sensitive to 5-fluorouracil

References:

Genotypes:

FYPO:0009067 - sensitive to amorolfine

References:

Genotypes:

FYPO:0000104 - sensitive to cycloheximide

References:

Genotypes:

FYPO:0007931 - sensitive to egtazic acid

References:

Genotypes:

FYPO:0000842 - sensitive to ethanol during vegetative growth

References:

Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

References:

Genotypes:

FYPO:0009071 - sensitive to itraconazole

References:

Genotypes:

FYPO:0001719 - sensitive to lithium

References:

Genotypes:

FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0006836 - sensitive to magnesium chloride

References:

Genotypes:

FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0001214 - sensitive to potassium chloride

References:

Genotypes:

FYPO:0000111 - sensitive to rapamycin

References:

Genotypes:

FYPO:0005889 - sensitive to sodium chloride

References:

Genotypes:

FYPO:0009090 - sensitive to sodium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0000841 - sensitive to sodium dodecyl sulfate

References:

Genotypes:

FYPO:0002328 - sensitive to terbinafine

References:

Genotypes:

FYPO:0000115 - sensitive to valproic acid

References:

Genotypes:

FYPO:0009063 - sensitive to X-rays during vegetative growth

References:

Genotypes:

FYPO:0002438 - short, misoriented actin cables

References:

Genotypes:

FYPO:0001234 - slow vegetative cell population growth

References:

Genotypes:

FYPO:0002792 - small vacuoles present in increased numbers during cellular hypotonic response

References:

Genotypes:

FYPO:0000021 - spheroid vegetative cell

References:

Genotypes:

FYPO:0000024 - stubby vegetative cell

References:

Genotypes:

FYPO:0002380 - viable spheroid vegetative cell

References:

Genotypes:

FYPO:0002106 - viable stubby vegetative cell

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0006616 - viable vegetative cell with increased cell diameter

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

Protein features

IDNameInterPro nameDB name
PF00063Myosin_headMyosin_head_motor_dom-likePFAM
PF01843DILDilute_domPFAM
PF00612IQIQ_motif_EF-hand-BSPFAM
cd01380MYSc_Myo5MYSc_Myo5CDD
cd15474Myo5p-like_CBD_fungalCDD
PS51456MYOSIN_MOTORMyosin_head_motor_dom-likePROSITE_PROFILES
PS51844SH3_LIKESH3_MyosinPROSITE_PROFILES
PS50096IQPROSITE_PROFILES
PS51126DILUTEDilute_domPROSITE_PROFILES
SM01132DIL_2Dilute_domSMART
SM00015iq_5IQ_motif_EF-hand-BSSMART
SM00242MYSc_2aMyosin_head_motor_dom-likeSMART
PR00193MYOSINHEAVYMyosin_head_motor_dom-likePRINTS
G3DSA:1.10.10.820:FF:000001FUNFAM
G3DSA:1.20.5.190:FF:000001FUNFAM
SSF52540P-loop containing nucleoside triphosphate hydrolasesP-loop_NTPaseSUPERFAMILY
G3DSA:1.20.5.190GENE3D
G3DSA:1.20.58.530GENE3D
G3DSA:3.40.850.10Kinesin motor domainKinesin_motor_dom_sfGENE3D
G3DSA:1.10.10.820GENE3D
G3DSA:1.20.5.4820GENE3D
G3DSA:1.20.120.720Myosin VI head, motor domain, U50 subdomainGENE3D
PTHR13140MYOSINPANTHER
CoilCoilCOILS

Orthologs

References / Literature

GO_REF:0000002 - Comments
PMID:22891259 - Fission yeast Ags1 confers the essential septum strength needed for safe gradual cell abscission.
Cortés JC et al. J Cell Biol 2012 Aug 20;198(4):637-56
PMID:11509236 - Myosin V-mediated vacuole distribution and fusion in fission yeast.
Mulvihill DP et al. Curr Biol 2001 Jul 24;11(14):1124-7
PMID:19646873 - The conserved NDR kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42.
Das M et al. Curr Biol 2009 Aug 11;19(15):1314-9
PMID:19547744 - Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.
Beltrao P et al. PLoS Biol 2009 Jun 16;7(6):e1000134
PMID:21642440 - Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast.
Skau CT et al. J Biol Chem 2011 Jul 29;286(30):26964-77
PMID:23294323 - The Kin1 kinase and the calcineurin phosphatase cooperate to link actin ring assembly and septum synthesis in fission yeast.
Cadou A et al. Biol Cell 2013 Mar;105(3):129-48
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:28784611 - Phosphoinositide-mediated ring anchoring resists perpendicular forces to promote medial cytokinesis.
Snider CE et al. J Cell Biol 2017 Oct 02;216(10):3041-3050
PMID:31495586 - Capping Protein Insulates Arp2/3-Assembled Actin Patches from Formins.
Billault-Chaumartin I et al. Curr Biol 2019 Oct 07;29(19):3165-3176.e6
PMID:27852900 - Gradients of phosphatidylserine contribute to plasma membrane charge localization and cell polarity in fission yeast.
Haupt A et al. Mol Biol Cell 2017 Jan 01;28(1):210-220
PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.
Halova L et al. Open Biol 2021 Apr;11(4):200405
PMID:25411334 - The Rho-GEF Gef3 interacts with the septin complex and activates the GTPase Rho4 during fission yeast cytokinesis.
Wang N et al. Mol Biol Cell 2015 Jan 15;26(2):238-55
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:24954052 - Formins determine the functional properties of actin filaments in yeast.
Johnson M et al. Curr Biol 2014 Jul 07;24(13):1525-30
PMID:34250083 - Barcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast.
Romila CA et al. Microb Cell 2021 Jul 05;8(7):146-160
PMID:11359928 - Identification of two type V myosins in fission yeast, one of which functions in polarized cell growth and moves rapidly in the cell.
Motegi F et al. Mol Biol Cell 2001 May;12(5):1367-80
PMID:22137473 - Shaping fission yeast cells by rerouting actin-based transport on microtubules.
Lo Presti L et al. Curr Biol 2011 Dec 20;21(24):2064-9
PMID:27798845 - Spatial focalization of pheromone/MAPK signaling triggers commitment to cell-cell fusion.
Dudin O et al. Genes Dev 2016 Oct 01;30(19):2226-2239
PMID:22768263 - Fission yeast Sec3 and Exo70 are transported on actin cables and localize the exocyst complex to cell poles.
Bendezú FO et al. PLoS One 2012;7(6):e40248
PMID:21849474 - Spatial control of Cdc42 activation determines cell width in fission yeast.
Kelly FD et al. Mol Biol Cell 2011 Oct;22(20):3801-11
PMID:30201262 - Fission yeast Adf1 is necessary for reassembly of actin filaments into the contractile ring during cytokinesis.
Ueda EI et al. Biochem Biophys Res Commun 2018 Nov 25;506(2):330-338
PMID:16421926 - A critical role for the type V myosin, Myo52, in septum deposition and cell fission during cytokinesis in Schizosaccharomyces pombe.
Mulvihill DP et al. Cell Motil Cytoskeleton 2006 Mar;63(3):149-61
PMID:24146635 - Hsp70-Hsp40 chaperone complex functions in controlling polarized growth by repressing Hsf1-driven heat stress-associated transcription.
Vjestica A et al. PLoS Genet 2013;9(10):e1003886
PMID:24196839 - Fission yeast tropomyosin specifies directed transport of myosin-V along actin cables.
Clayton JE et al. Mol Biol Cell 2014 Jan;25(1):66-75
PMID:27082518 - Roles of the TRAPP-II Complex and the Exocyst in Membrane Deposition during Fission Yeast Cytokinesis.
Wang N et al. PLoS Biol 2016 Apr;14(4):e1002437
PMID:28410370 - A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.
Dudin O et al. PLoS Genet 2017 Apr;13(4):e1006721
PMID:26941334 - Unique spatiotemporal activation pattern of Cdc42 by Gef1 and Scd1 promotes different events during cytokinesis.
Wei B et al. Mol Biol Cell 2016 Apr 15;27(8):1235-45
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:29134248 - The ancient claudin Dni2 facilitates yeast cell fusion by compartmentalizing Dni1 into a membrane subdomain.
Curto MÁ et al. Cell Mol Life Sci 2018 May;75(9):1687-1706
PMID:29290560 - ER-PM Contacts Restrict Exocytic Sites for Polarized Morphogenesis.
Ng AYE et al. Curr Biol 2018 Jan 08;28(1):146-153.e5
PMID:19098712 - Rng3, a member of the UCS family of myosin co-chaperones, associates with myosin heavy chains cotranslationally.
Amorim MJ et al. EMBO Rep 2009 Feb;10(2):186-91
PMID:19808886 - Myosin V spatially regulates microtubule dynamics and promotes the ubiquitin-dependent degradation of the fission yeast CLIP-170 homologue, Tip1.
Martín-García R et al. J Cell Sci 2009 Nov 01;122(Pt 21):3862-72
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:25651869 - Chemical genomics approach to identify genes associated with sensitivity to rapamycin in the fission yeast Schizosaccharomyces pombe.
Doi A et al. Genes Cells 2015 Apr;20(4):292-309
PMID:19543678 - Polycystic kidney disease channel and synaptotagmin homologues play roles in schizosaccharomyces pombe cell wall synthesis/repair and membrane protein trafficking.
Aydar E et al. J Membr Biol 2009 Jun;229(3):141-52
PMID:30355493 - Expanded Interactome of the Intrinsically Disordered Protein Dss1.
Schenstrøm SM et al. Cell Rep 2018 Oct 23;25(4):862-870
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
PMID:27918601 - Identifying genes required for respiratory growth of fission yeast.
Malecki M et al. Wellcome Open Res 2016;1:12
PMID:22891673 - Fission yeast sec3 bridges the exocyst complex to the actin cytoskeleton.
Jourdain I et al. Traffic 2012 Nov;13(11):1481-95
PMID:34382996 - Ultrastructural plasma membrane asymmetries in tension and curvature promote yeast cell fusion.
Muriel O et al. J Cell Biol 2021 Oct 04;220(10)
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:18003699 - In vivo movement of the type V myosin Myo52 requires dimerisation but is independent of the neck domain.
Grallert A et al. J Cell Sci 2007 Dec 01;120(Pt 23):4093-8
PMID:11112691 - Two type V myosins with non-overlapping functions in the fission yeast Schizosaccharomyces pombe: Myo52 is concerned with growth polarity and cytokinesis, Myo51 is a component of the cytokinetic actin ring.
Win TZ et al. J Cell Sci 2001 Jan;114(Pt 1):69-79
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:29996109 - Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.
Swaffer MP et al. Cell Rep 2018 Jul 10;24(2):503-514
PMID:18257517 - Phosphoproteome analysis of fission yeast.
Wilson-Grady JT et al. J Proteome Res 2008 Mar;7(3):1088-97
PMID:34666001 - Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast.
Neeli-Venkata R et al. Dev Cell 2021 Oct 25;56(20):2856-2870.e7
PMID:25825517 - A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast.
Dudin O et al. J Cell Biol 2015 Mar 30;208(7):897-911
PMID:21712547 - Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast.
Koch A et al. Sci Signal 2011 Jun 28;4(179):rs6
PMID:19371376 - Schizosaccharomyces pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor.
Hanyu Y et al. Genes Cells 2009 May;14(5):539-54
PMID:21340088 - Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.
Arita Y et al. Mol Biosyst 2011 May;7(5):1463-72
PMID:24531330 - Getting myosin-V on the right track: tropomyosin sorts transport in yeast.
Pollard LW et al. Bioarchitecture 2014;4(1):35-8
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.
Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963
PMID:34910579 - Involvement of Smi1 in cell wall integrity and glucan synthase Bgs4 localization during fission yeast cytokinesis.
Longo LVG et al. Mol Biol Cell 2022 Feb 01;33(2):ar17
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23200991 - Cdc42 explores the cell periphery for mate selection in fission yeast.
Bendezú FO et al. Curr Biol 2013 Jan 07;23(1):42-7
PMID:24798735 - The novel proteins Rng8 and Rng9 regulate the myosin-V Myo51 during fission yeast cytokinesis.
Wang N et al. J Cell Biol 2014 May 12;205(3):357-75
PMID:36202103 - Condensation of the fusion focus by the intrinsically disordered region of the formin Fus1 is essential for cell-cell fusion.
Billault-Chaumartin I et al. Curr Biol 2022 Nov 07;32(21):4752-4761.e10
PMID:30318352 - A Positive Feedback between Growth and Polarity Provides Directional Persistency and Flexibility to the Process of Tip Growth.
Haupt A et al. Curr Biol 2018 Oct 22;28(20):3342-3351.e3
PMID:23041194 - Plasma membrane tethering of the cortical ER necessitates its finely reticulated architecture.
Zhang D et al. Curr Biol 2012 Nov 06;22(21):2048-52
PMID:23051734 - Myosin Vs organize actin cables in fission yeast.
Lo Presti L et al. Mol Biol Cell 2012 Dec;23(23):4579-91
PMID:25483073 - Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.
Mojardín L et al. Cell Cycle 2015;14(2):206-18
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:19805578 - Genome-wide mapping of myosin protein-RNA networks suggests the existence of specialized protein production sites.
Mata J FASEB J 2010 Feb;24(2):479-84
PMID:21148300 - Actin cables and the exocyst form two independent morphogenesis pathways in the fission yeast.
Bendezú FO et al. Mol Biol Cell 2011 Jan 01;22(1):44-53
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.
Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:27022830 - Microscopy of Fission Yeast Sexual Lifecycle.
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PMID:16772338 - The fission yeast Chs2 protein interacts with the type-II myosin Myo3p and is required for the integrity of the actomyosin ring.
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