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protein coding gene - tim9 (SPCC24B10.05) - Tim9-Tim10 complex subunit Tim9

Gene summary

Standard name
tim9
Systematic ID
SPCC24B10.05
Product
Tim9-Tim10 complex subunit Tim9
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
Q9P7K0
ORFeome ID
04/04F07
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome III: 908922..909714 forward strand

Annotation

GO biological process

GO:7770063 - beta barrel protein insertion into mitochondrial outer membrane

References:

GO:7770061 - TOM-TIM22-mediated mitochondrial inner membrane protein insertion

References:

GO cellular component

GO:7770105 - Tim9-Tim10 complex

References:

GO molecular function

GO:0140309 - unfolded protein holdase activity

References:

Modification

MOD:00689 - disulfide crosslinked residues

References:

MOD:01148 - ubiquitinylated lysine

References:

Protein features

PBO:0111806 - zf-Tim10/DDP type

PBO:0111743 - zinc finger protein

Qualitative gene expression

PomGeneEx:0000012 - RNA level decreased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0000214 - gene structure may be incorrect

Protein features

IDNameInterPro nameDB name
PF02953zf-Tim10_DDPTim10-likePfam
G3DSA:1.10.287.810Tim10-like_dom_sfCATH-Gene3D
SSF144122Tim10-like_dom_sfSUPERFAMILY
PTHR13172Mito_inner_translocase_subPANTHER

Orthologs

References / Literature

PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.
UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.
Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
PMID:16537923 - Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.
Todd BL et al. Mol Cell Biol 2006 Apr;26(7):2817-31
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:36478272 - Translation-complex profiling of fission yeast cells reveals dynamic rearrangements of scanning ribosomal subunits upon nutritional stress.
Duncan CDS et al. Nucleic Acids Res 2022 Dec 09;50(22):13011-13025
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623