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protein coding gene - mto1 (SPCC417.07c) - gamma tubulin complex linker Mto1

Gene summary

Standard name
mto1
Systematic ID
SPCC417.07c
Product
gamma tubulin complex linker Mto1
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
mbo1, mod20
UniProt ID
O94488
ORFeome ID
30/30D06
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome III: 1679761..1683271 reverse strand

Annotation

Disease association

MONDO:0001149 - microcephaly

References:

MONDO:0011488 - microcephaly 3, primary, autosomal recessive

References:

GO biological process

GO:0030954 - astral microtubule nucleation

References:

GO:0072766 - centromere clustering at the mitotic interphase nuclear envelope

References:

GO:0030989 - dynein-driven meiotic oscillatory nuclear movement

References:

GO:0040001 - establishment of mitotic spindle localization

References:

GO:0000742 - karyogamy involved in conjugation with cellular fusion

References:

GO:0051415 - microtubule nucleation by interphase microtubule organizing center

References:

GO:0098863 - nuclear migration by microtubule mediated pushing forces

References:

GO:0140405 - spindle pole body-led chromosome movement during mitotic interphase

References:

GO cellular component

GO:0000923 - equatorial microtubule organizing center

References:

GO:0061496 - half bridge of mitotic spindle pole body

References:

GO:0031021 - interphase microtubule organizing center

References:

GO:0015630 - microtubule cytoskeleton

References:

GO:0120104 - mitotic actomyosin contractile ring, proximal layer

References:

GO:0044732 - mitotic spindle pole body

References:

GO:0061499 - outer plaque of mitotic spindle pole body

References:

GO:0099070 - static microtubule bundle

References:

GO:0005634 - nucleus

References:

GO molecular function

GO:0005516 - calmodulin binding

References:

GO:0106006 - cytoskeletal protein-membrane anchor activity

References:

GO:0005515 - protein binding

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

MOD:00047 - O-phospho-L-threonine

References:

MOD:00048 - O4'-phospho-L-tyrosine

References:

MOD:01148 - ubiquitinylated lysine

References:

Multi-locus phenotype

FYPO:0000620 - abnormal cell cycle arrest in mitotic metaphase

References:

Genotypes:

FYPO:0001779 - abnormal centromere clustering at nuclear periphery during vegetative growth

References:

Genotypes:

FYPO:0006760 - abnormal centromere detachment from spindle pole body during meiotic chromosome organization

References:

Genotypes:

FYPO:0006770 - abnormal kinetochore disassembly during meiotic prophase I

References:

Genotypes:

FYPO:0005719 - abolished mitotic metaphase chromosome recapture

References:

Genotypes:

FYPO:0008202 - equational sister chromatid separation at meiosis I

References:

Genotypes:

FYPO:0006102 - interphase microtubules absent from cell

References:

Genotypes:

FYPO:0008233 - microtubule bundles present in normal numbers

References:

Genotypes:

FYPO:0000644 - normal protein localization during vegetative growth

References:

Genotypes:

FYPO:0008234 - normal protein localization to cytoplasmic puncta

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0000089 - sensitive to methyl methanesulfonate

References:

Genotypes:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0003013 - abnormal actomyosin contractile ring disassembly

References:

Genotypes:

FYPO:0000325 - abnormal attachment of spindle microtubules to kinetochore

References:

Genotypes:

FYPO:0002029 - abnormal cell division, large and small daughter cells

References:

Genotypes:

FYPO:0001779 - abnormal centromere clustering at nuclear periphery during vegetative growth

References:

Genotypes:

FYPO:0006760 - abnormal centromere detachment from spindle pole body during meiotic chromosome organization

References:

Genotypes:

FYPO:0000234 - abnormal cytoplasmic interphase microtubule nucleation

References:

Genotypes:

FYPO:0000197 - abnormal horsetail movement

References:

Genotypes:

FYPO:0006101 - abnormal interphase microtubules

References:

Genotypes:

FYPO:0006770 - abnormal kinetochore disassembly during meiotic prophase I

References:

Genotypes:

FYPO:0000151 - abnormal meiotic chromosome segregation

References:

Genotypes:

FYPO:0005565 - abnormal microtubule bundle during G0 to G1 transition

References:

Genotypes:

FYPO:0002824 - abnormal protein localization to mitotic spindle

References:

Genotypes:

FYPO:0009108 - abnormal spindle pole body orientation during mitotic telophase

References:

Genotypes:

FYPO:0001894 - abnormal sporulation resulting in formation of ascus with more or fewer than four spores

References:

Genotypes:

FYPO:0003263 - abnormal sporulation resulting in formation of ascus with more than four spores

References:

Genotypes:

FYPO:0004766 - abolished cytoplasmic interphase microtubule nucleation

References:

Genotypes:

FYPO:0005697 - abolished cytoplasmic interphase microtubule nucleation from spindle pole body

References:

Genotypes:

FYPO:0004616 - abolished cytoplasmic microtubule depolymerization at plus end at cell tip

References:

Genotypes:

FYPO:0005696 - abolished cytoplasmic microtubule nucleation from iMTOC

References:

Genotypes:

FYPO:0006366 - abolished meiotic telomere clustering

References:

Genotypes:

FYPO:0004613 - abolished microtubule attachment to spindle pole body

References:

Genotypes:

FYPO:0004622 - abolished mitotic spindle disassembly

References:

Genotypes:

FYPO:0005700 - abolished protein localization to eMTOC

References:

Genotypes:

FYPO:0005701 - abolished protein localization to iMTOC

References:

Genotypes:

FYPO:0000705 - abolished protein-protein interaction

References:

Genotypes:

FYPO:0007192 - abolished spindle pole body-led chromosome movement during mitotic interphase

References:

Genotypes:

FYPO:0004618 - astral microtubules absent from cell

References:

Genotypes:

FYPO:0003327 - curved interphase microtubules

References:

Genotypes:

FYPO:0004728 - cytoplasmic microtubule formation from nuclear microtubules following nuclear envelope breakthrough

References:

Genotypes:

FYPO:0004619 - cytoplasmic microtubules nucleated from eMTOC absent from cell

References:

Genotypes:

FYPO:0003743 - decreased cell population growth during glucose starvation

References:

Genotypes:

FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

References:

Genotypes:

FYPO:0006921 - decreased gene conversion at mitotic DNA replication fork barriers

References:

Genotypes:

FYPO:0000185 - decreased gene conversion during vegetative growth

References:

Genotypes:

FYPO:0005694 - decreased interphase microtubule nucleation

References:

Genotypes:

FYPO:0005386 - decreased protein localization to chromatin at chromosome arms

References:

Genotypes:

FYPO:0006182 - decreased protein localization to interphase microtubule

References:

Genotypes:

FYPO:0007209 - decreased sister chromatid cohesion along chromosome arms during mitotic interphase

References:

Genotypes:

FYPO:0005691 - decreased spindle pole body-led chromosome movement during mitotic interphase

References:

Genotypes:

FYPO:0000584 - decreased sporulation frequency

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0008006 - dynamic microtubule minus ends in interphase bundles

References:

Genotypes:

FYPO:0002638 - increased activation of mitotic spindle assembly checkpoint

References:

Genotypes:

FYPO:0009103 - increased actomyosin contractile ring recoil distance after ring ablation

References:

Genotypes:

FYPO:0009104 - increased actomyosin contractile ring recoil time after ring ablation

References:

Genotypes:

FYPO:0009077 - increased cell population growth on ethanol carbon source

References:

Genotypes:

FYPO:0005261 - increased cell population growth on galactose carbon source

References:

Genotypes:

FYPO:0004167 - increased cell population growth on glycerol carbon source

References:

Genotypes:

FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

References:

Genotypes:

FYPO:0009096 - increased cell population growth on xylose carbon source

References:

Genotypes:

FYPO:0007191 - increased duration of Rad52 focus presence during vegetative growth

References:

Genotypes:

FYPO:0009107 - increased nuclear movement velocity during mitotic telophase

References:

Genotypes:

FYPO:0000972 - increased number of Rad52 foci during vegetative growth

References:

Genotypes:

FYPO:0003580 - increased number of Sad1 foci during response to DNA damage

References:

Genotypes:

FYPO:0002852 - increased protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0006897 - increased rate of actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0004557 - increased vegetative cell population growth

References:

Genotypes:

FYPO:0009102 - interphase microtubules present in decreased numbers

References:

Genotypes:

FYPO:0004511 - long curved interphase microtubules

References:

Genotypes:

FYPO:0003787 - long mitotic spindle microtubules protruding beyond spindle pole body

References:

Genotypes:

FYPO:0004724 - long nuclear microtubules protruding through nuclear envelope during interphase

References:

Genotypes:

FYPO:0002444 - loss of punctate cytoplasmic protein localization

References:

Genotypes:

FYPO:0006518 - loss of viability in G0

References:

Genotypes:

FYPO:0000245 - loss of viability in stationary phase

References:

Genotypes:

FYPO:0003061 - meiotic cell cycle in zygote with unfused nuclei

References:

Genotypes:

FYPO:0002818 - microtubule bundles present in decreased numbers

References:

Genotypes:

FYPO:0005686 - microtubule bundles present in decreased numbers during mitotic interphase

References:

Genotypes:

FYPO:0001369 - mislocalized actomyosin contractile ring

References:

Genotypes:

FYPO:0000339 - mislocalized septum during vegetative growth

References:

Genotypes:

FYPO:0007388 - misoriented mitotic spindle

References:

Genotypes:

FYPO:0001390 - misoriented septum during vegetative growth

References:

Genotypes:

FYPO:0000324 - mitotic metaphase/anaphase transition delay

References:

Genotypes:

FYPO:0003717 - normal actin cytoskeleton morphology during vegetative growth

References:

Genotypes:

FYPO:0001368 - normal actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0007828 - normal actomyosin contractile ring maturation

References:

Genotypes:

FYPO:0006995 - normal chromatin silencing at centromere inner repeat

References:

Genotypes:

FYPO:0004742 - normal chromatin silencing at centromere outer repeat

References:

Genotypes:

FYPO:0003555 - normal chromatin silencing at subtelomere

References:

Genotypes:

FYPO:0004310 - normal duration of mitotic M phase

References:

Genotypes:

FYPO:0007553 - normal G1 to G0 transition

References:

Genotypes:

FYPO:0002826 - normal gamma-tubulin complex assembly

References:

Genotypes:

FYPO:0000969 - normal growth during cellular response to UV

References:

Genotypes:

FYPO:0000963 - normal growth on hydroxyurea

References:

Genotypes:

FYPO:0000957 - normal growth on methyl methanesulfonate

References:

Genotypes:

FYPO:0005699 - normal interphase microtubule nucleation from spindle pole body

References:

Genotypes:

FYPO:0006004 - normal interphase microtubule organization

References:

Genotypes:

FYPO:0001400 - normal interphase microtubules

References:

Genotypes:

FYPO:0001399 - normal mitotic spindle

References:

Genotypes:

FYPO:0004726 - normal mitotic spindle orientation correction

References:

Genotypes:

FYPO:0004722 - normal nuclear microtubules

References:

Genotypes:

FYPO:0006917 - normal onset of mitotic metaphase/anaphase transition

References:

Genotypes:

FYPO:0003332 - normal protein kinase activity during mitotic interphase

References:

Genotypes:

FYPO:0000833 - normal protein level during vegetative growth

References:

Genotypes:

FYPO:0000644 - normal protein localization during vegetative growth

References:

Genotypes:

FYPO:0005707 - normal protein localization to eMTOC

References:

Genotypes:

FYPO:0005708 - normal protein localization to iMTOC

References:

Genotypes:

FYPO:0004731 - normal protein localization to interphase microtubule plus-end

References:

Genotypes:

FYPO:0002967 - normal protein localization to mitotic spindle pole body

References:

Genotypes:

FYPO:0005709 - normal protein localization to mitotic spindle pole body during mitosis

References:

Genotypes:

FYPO:0000703 - normal protein-protein interaction

References:

Genotypes:

FYPO:0004895 - normal rate of actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0004429 - normal rate of mitotic spindle elongation

References:

Genotypes:

FYPO:0009106 - nucleus mislocalized towards cell equator during mitotic telophase

References:

Genotypes:

FYPO:0003302 - nucleus mislocalized towards cell tip during mitotic interphase

References:

Genotypes:

FYPO:0006338 - nucleus mislocalized towards cell tip during mitotic telophase

References:

Genotypes:

FYPO:0003264 - overlapping meiosis I spindles

References:

Genotypes:

FYPO:0003126 - post-anaphase array absent from cell

References:

Genotypes:

FYPO:0004730 - protein mislocalized to lateral cell cortex

References:

Genotypes:

FYPO:0009041 - resistance to 2,2′-dipyridyl

References:

Genotypes:

FYPO:0009036 - resistance to benzamidine

References:

Genotypes:

FYPO:0000067 - resistance to brefeldin A

References:

Genotypes:

FYPO:0000763 - resistance to cadmium

References:

Genotypes:

FYPO:0002693 - resistance to diamide

References:

Genotypes:

FYPO:0009038 - resistance to egtazic acid

References:

Genotypes:

FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0005968 - resistance to sodium chloride

References:

Genotypes:

FYPO:0001034 - resistance to tunicamycin

References:

Genotypes:

FYPO:0000830 - resistance to vanadate

References:

Genotypes:

FYPO:0003595 - S-shaped cell

References:

Genotypes:

FYPO:0009067 - sensitive to amorolfine

References:

Genotypes:

FYPO:0000094 - sensitive to benomyl

References:

Genotypes:

FYPO:0000095 - sensitive to bleomycin

References:

Genotypes:

FYPO:0000085 - sensitive to camptothecin

References:

Genotypes:

FYPO:0000104 - sensitive to cycloheximide

References:

Genotypes:

FYPO:0000799 - sensitive to diamide

References:

Genotypes:

FYPO:0007931 - sensitive to egtazic acid

References:

Genotypes:

FYPO:0000842 - sensitive to ethanol during vegetative growth

References:

Genotypes:

FYPO:0000087 - sensitive to hydrogen peroxide

References:

Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

References:

Genotypes:

FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

References:

Genotypes:

FYPO:0009071 - sensitive to itraconazole

References:

Genotypes:

FYPO:0001719 - sensitive to lithium

References:

Genotypes:

FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

References:

Genotypes:

FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0006836 - sensitive to magnesium chloride

References:

Genotypes:

FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0000089 - sensitive to methyl methanesulfonate

References:

Genotypes:

FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0005252 - sensitive to tamoxifen

References:

Genotypes:

FYPO:0002701 - sensitive to torin1

References:

Genotypes:

FYPO:0001457 - sensitive to tunicamycin

References:

Genotypes:

FYPO:0003656 - sensitive to vanadate

References:

Genotypes:

FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

References:

Genotypes:

FYPO:0003429 - short interphase microtubules present in decreased numbers

References:

Genotypes:

FYPO:0005567 - T-shaped cell during G0 to G1 transition

References:

Genotypes:

FYPO:0004723 - transiently misoriented mitotic spindle

References:

Genotypes:

FYPO:0002112 - viable curved vegetative cell

References:

Genotypes:

FYPO:0002456 - viable curved vegetative cell with abnormal septum

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0003777 - primary name changed

Protein features

IDNameInterPro nameDB name
PF07989Cnn_1NCnn_1NPfam
PF12808Mto2_bdgMto1-like_Mto2p-bdPfam
G3DSA:1.10.287.1490CATH-Gene3D
CoilCOILS
mobidb-lite-Disorderdisorder_predictionMobiDB-Disorder
mobidb-lite-Low-complexitydisorder_predictionMobiDB-Low-complexity
mobidb-lite-Polardisorder_predictionMobiDB-Polar
mobidb-lite-Polyampholytedisorder_predictionMobiDB-Polyampholyte

Orthologs

References / Literature

PMID:29996109 - Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.
Swaffer MP et al. Cell Rep 2018 Jul 10;24(2):503-514
PMID:18495844 - Interphase microtubule bundles use global cell shape to guide spindle alignment in fission yeast.
Daga RR et al. J Cell Sci 2008 Jun 15;121(Pt 12):1973-80
PMID:39471327 - New mutations in the core Schizosaccharomyces pombe spindle pole body scaffold Ppc89 reveal separable functions in regulating cell division.
Hanna SM et al. G3 (Bethesda) 2024 Oct 29;
PMID:25422470 - Oscillatory AAA+ ATPase Knk1 constitutes a novel morphogenetic pathway in fission yeast.
Scheffler K et al. Proc Natl Acad Sci U S A 2014 Dec 16;111(50):17899-904
PMID:18257517 - Phosphoproteome analysis of fission yeast.
Wilson-Grady JT et al. J Proteome Res 2008 Mar;7(3):1088-97
PMID:15800064 - Mto2p, a novel fission yeast protein required for cytoplasmic microtubule organization and anchoring of the cytokinetic actin ring.
Venkatram S et al. Mol Biol Cell 2005 Jun;16(6):3052-63
PMID:16096637 - Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis.
Kanai M et al. EMBO J 2005 Sep 07;24(17):3012-25
PMID:26243668 - Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis.
Borek WE et al. Nat Commun 2015 Aug 05;6:7929
PMID:19001497 - Two distinct regions of Mto1 are required for normal microtubule nucleation and efficient association with the gamma-tubulin complex in vivo.
Samejima I et al. J Cell Sci 2008 Dec 01;121(Pt 23):3971-80
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:29259000 - Genes Important for Schizosaccharomyces pombe Meiosis Identified Through a Functional Genomics Screen.
Blyth J et al. Genetics 2018 Feb;208(2):589-603
PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.
Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704
PMID:24463365 - Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.
Rallis C et al. Biol Open 2014 Feb 15;3(2):161-71
PMID:26124291 - A stable microtubule array drives fission yeast polarity reestablishment upon quiescence exit.
Laporte D et al. J Cell Biol 2015 Jul 06;210(1):99-113
PMID:19111658 - HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms.
Motamedi MR et al. Mol Cell 2008 Dec 26;32(6):778-90
PMID:24704079 - Activation of the γ-tubulin complex by the Mto1/2 complex.
Lynch EM et al. Curr Biol 2014 Apr 14;24(8):896-903
PMID:20970338 - Fission yeast Mto1 regulates diversity of cytoplasmic microtubule organizing centers.
Samejima I et al. Curr Biol 2010 Nov 09;20(21):1959-65
PMID:29958883 - Role of nucleocytoplasmic transport in interphase microtubule organization in fission yeast.
Kume K et al. Biochem Biophys Res Commun 2018 Sep 05;503(2):1160-1167
PMID:25210736 - Dynamics of cell shape inheritance in fission yeast.
Abenza JF et al. PLoS One 2014;9(9):e106959
PMID:21652630 - Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.
Snaith HA et al. J Cell Sci 2011 Jul 01;124(Pt 13):2187-99
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:37099380 - Microtubule competition and cell growth recenter the nucleus after anaphase in fission yeast.
Bellingham-Johnstun K et al. Mol Biol Cell 2023 Jul 01;34(8):ar77
PMID:15837798 - Efficient formation of bipolar microtubule bundles requires microtubule-bound gamma-tubulin complexes.
Janson ME et al. J Cell Biol 2005 Apr 25;169(2):297-308
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
Pfam:PF07989 - Unknown title
PMID:30355493 - Expanded Interactome of the Intrinsically Disordered Protein Dss1.
Schenstrøm SM et al. Cell Rep 2018 Oct 23;25(4):862-870
PMID:15772152 - Effects of {gamma}-tubulin complex proteins on microtubule nucleation and catastrophe in fission yeast.
Zimmerman S et al. Mol Biol Cell 2005 Jun;16(6):2719-33
PMID:28974540 - The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components.
Salas-Pino S et al. J Cell Biol 2017 Nov 06;216(11):3591-3608
PMID:34296454 - The TOR-dependent phosphoproteome and regulation of cellular protein synthesis.
Mak T et al. EMBO J 2021 Aug 16;40(16):e107911
PMID:37783794 - An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrity.
Ader NR et al. Nat Cell Biol 2023 Oct;25(10):1465-1477
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:15120067 - Microtubule nucleation at non-spindle pole body microtubule-organizing centers requires fission yeast centrosomin-related protein mod20p.
Sawin KE et al. Curr Biol 2004 May 04;14(9):763-75
PMID:28218250 - Chromatin remodeller Fun30 Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.
Lee J et al. Nat Commun 2017 Feb 20;8:14527
PB_REF:0000003 - Disease Association Curation
PMID:39476757 - Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.
Cipak L et al. Biochem Biophys Res Commun 2024 Oct 25;736:150895
PMID:18562692 - Latrunculin A delays anaphase onset in fission yeast by disrupting an Ase1-independent pathway controlling mitotic spindle stability.
Meadows JC et al. Mol Biol Cell 2008 Sep;19(9):3713-23
PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.
Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963
PMID:21712547 - Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast.
Koch A et al. Sci Signal 2011 Jun 28;4(179):rs6
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:21444751 - Microtubule stabilization in vivo by nucleation-incompetent γ-tubulin complex.
Anders A et al. J Cell Sci 2011 Apr 15;124(Pt 8):1207-13
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:27984725 - CDK Substrate Phosphorylation and Ordering the Cell Cycle.
Swaffer MP et al. Cell 2016 Dec 15;167(7):1750-1761.e16
PMID:17881496 - The Dam1/DASH complex is required for the retrieval of unclustered kinetochores in fission yeast.
Franco A et al. J Cell Sci 2007 Oct 01;120(Pt 19):3345-51
PMID:24055157 - CK1 is required for a mitotic checkpoint that delays cytokinesis.
Johnson AE et al. Curr Biol 2013 Oct 07;23(19):1920-6
PMID:16111942 - Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement.
Tanaka K et al. Curr Biol 2005 Aug 23;15(16):1479-86
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.
Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:27611693 - A Taz1- and Microtubule-Dependent Regulatory Relationship between Telomere and Centromere Positions in Bouquet Formation Secures Proper Meiotic Divisions.
Katsumata K et al. PLoS Genet 2016 Sep;12(9):e1006304
PMID:30321377 - Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome.
Telekawa C et al. Nucleic Acids Res 2018 Nov 30;46(21):11169-11183
PMID:30427751 - The J-domain cochaperone Rsp1 interacts with Mto1 to organize noncentrosomal microtubule assembly.
Shen J et al. Mol Biol Cell 2019 Jan 15;30(2):256-267
PMID:15659644 - Fission yeast mto2p regulates microtubule nucleation by the centrosomin-related protein mto1p.
Samejima I et al. Mol Biol Cell 2005 Jun;16(6):3040-51
PMID:33260998 - High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence.
Zahedi Y et al. Int J Mol Sci 2020 Nov 27;21(23)
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
PMID:18061564 - Stabilization of overlapping microtubules by fission yeast CLASP.
Bratman SV et al. Dev Cell 2007 Dec;13(6):812-27
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:26628015 - Characterization of Tamoxifen as an Antifungal Agent Using the Yeast Schizosaccharomyces Pombe Model Organism.
Zhang X et al. Kobe J Med Sci 2015 Oct 09;61(2):E54-63
PMID:31483748 - Effects of the microtubule nucleator Mto1 on chromosomal movement, DNA repair, and sister chromatid cohesion in fission yeast.
Zhurinsky J et al. Mol Biol Cell 2019 Oct 01;30(21):2695-2708
PMID:24196444 - Mal3, the Schizosaccharomyces pombe homolog of EB1, is required for karyogamy and for promoting oscillatory nuclear movement during meiosis.
Polakova S et al. Cell Cycle 2014;13(1):72-7
PMID:39833200 - Centromere positioning orchestrates telomere bouquet formation and the initiation of meiotic differentiation.
Jiménez-Martín A et al. Nat Commun 2025 Jan 20;16(1):837
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