protein coding gene - qcr7 (SPCC737.02c) - ubiquinol-cytochrome-c reductase complex subunit 6

Gene summary

Standard name

qcr7

Systematic ID

SPCC737.02c

Product

ubiquinol-cytochrome-c reductase complex subunit 6

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

O74533

ORFeome ID

03/03C05

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome III: 1886995..1888049 reverse strand

Annotation

Protein features

Orthologs

• UQCRB (HGNC:12582) Homo sapiens
• qcr7 (SJAG_03490) Schizosaccharomyces japonicus
• QCR7 (YDR529C) Saccharomyces cerevisiae

References / Literature

GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference

PMID:27886462 - Loss of ppr3, ppr4, ppr6, or ppr10 perturbs iron homeostasis and leads to apoptotic cell death in Schizosaccharomyces pombe.

Su Y et al. FEBS J 2017 Jan;284(2):324-337

PMID:16537923 - Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.

Todd BL et al. Mol Cell Biol 2006 Apr;26(7):2817-31

PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs

PB_REF:0000003 - Disease Association Curation

GO_REF:0000108 - Automatic assignment of GO terms using logical inference, based on on inter-ontology links.

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:22235339 - The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Lando D et al. PLoS One 2012;7(1):e29765

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:25375137 - Systematic analysis of the role of RNA-binding proteins in the regulation of RNA stability.

Hasan A et al. PLoS Genet 2014 Nov;10(11):e1004684

PMID:37939086 - Structure and function of the S. pombe III-IV-cyt c supercomplex.

Moe A et al. Proc Natl Acad Sci U S A 2023 Nov 14;120(46):e2307697120

GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.

Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7

GO_REF:0000033 - Annotation inferences using phylogenetic trees

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:25552606 - Identification of new players in cell division, DNA damage response, and morphogenesis through construction of Schizosaccharomyces pombe deletion strains.

Chen JS et al. G3 (Bethesda) 2014 Dec 31;5(3):361-70

PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.

Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:29996109 - Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.

Swaffer MP et al. Cell Rep 2018 Jul 10;24(2):503-514

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:38272226 - E3 ubiquitin ligase Hul6 modulates iron-dependent metabolism by regulating Php4 stability.

Yao R et al. J Biol Chem 2024 Jan 23;:105670