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protein coding gene - cox14 (SPCC757.15) - cytochrome c oxidase assembly protein Cox14

Gene summary

Standard name
cox14
Systematic ID
SPCC757.15
Product
cytochrome c oxidase assembly protein Cox14
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
C6Y4C7
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome III: 59097..60867 reverse strand

Annotation

Disease association

MONDO:0033639 - mitochondrial complex IV deficiency, nuclear type 10

References:

GO biological process

GO:0033617 - mitochondrial respiratory chain complex IV assembly

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GO cellular component

GO:0005743 - mitochondrial inner membrane

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Protein sequence feature

SO:0001812 - transmembrane_helix

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Quantitative gene expression

PBO:0006310 - protein level

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PBO:0011963 - RNA level

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Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

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PBO:0011071 - conserved in eukaryotes only

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PBO:0011064 - conserved in fungi

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PBO:0011069 - conserved in metazoa

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PBO:0011070 - conserved in vertebrates

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Warnings

PBO:0000082 - new gene

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Protein features

IDNameInterPro nameDB name
PF14880COX14COX14PFAM

Orthologs

References / Literature

GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:11152613 - Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
Krogh A et al. J Mol Biol 2001 Jan 19;305(3):567-80
PMID:39289458 - Characterization of Shy1, the Schizosaccharomyces pombe homolog of human SURF1.
Luo Y et al. Sci Rep 2024 Sep 17;14(1):21678
Pfam:PF14880 - Unknown title
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:18488015 - Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution.
Wilhelm BT et al. Nature 2008 Jun 26;453(7199):1239-43