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protein coding gene - for3 (SPCC895.05) - formin For3

Gene summary

Standard name
for3
Systematic ID
SPCC895.05
Product
formin For3
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
O94532
ORFeome ID
30/30G10
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome III: 1002750..1007515 forward strand

Annotation

Disease association

MONDO:0012196 - autosomal dominant auditory neuropathy 1

References:

MONDO:0010350 - premature ovarian failure 2A

References:

GO biological process

GO:0030036 - actin cytoskeleton organization

References:

GO:0061572 - actin filament bundle organization

References:

GO:0061245 - establishment or maintenance of bipolar cell polarity

References:

GO:1903475 - mitotic actomyosin contractile ring assembly

References:

GO cellular component

GO:0051285 - cell cortex of cell tip

References:

GO:1902716 - cell cortex of growing cell tip

References:

GO:0032153 - cell division site

References:

GO:0051286 - cell tip

References:

GO:0005737 - cytoplasm

References:

GO:0043332 - mating projection tip

References:

GO:0031097 - medial cortex

References:

GO:0036391 - medial cortex septin ring

References:

GO:0110085 - mitotic actomyosin contractile ring

References:

GO molecular function

GO:0051015 - actin filament binding

References:

GO:0031267 - small GTPase binding

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

MOD:00047 - O-phospho-L-threonine

References:

MOD:01148 - ubiquitinylated lysine

References:

Multi-locus phenotype

FYPO:0000161 - abnormal actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0002872 - abnormal endoplasmic reticulum localization

References:

Genotypes:

FYPO:0000742 - abnormal protein localization to actin cortical patch

References:

Genotypes:

FYPO:0000026 - abnormal vegetative cell polarity

References:

Genotypes:

FYPO:0002998 - abolished actomyosin contractile ring assembly, clumped medial cortical nodes

References:

Genotypes:

FYPO:0004105 - abolished polar cell growth

References:

Genotypes:

FYPO:0001585 - abolished protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0000537 - abolished protein secretion during vegetative growth

References:

Genotypes:

FYPO:0003315 - actin cables absent from cell

References:

Genotypes:

FYPO:0006030 - actin cortical patches absent from cell

References:

Genotypes:

FYPO:0001008 - actomyosin contractile ring absent

References:

Genotypes:

FYPO:0001407 - decreased cell population growth on glucose carbon source

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

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Genotypes:

FYPO:0003946 - delayed onset of protein localization to cell division site

References:

Genotypes:

FYPO:0000539 - increased protein secretion during vegetative growth

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Genotypes:

FYPO:0006897 - increased rate of actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0002482 - inviable spheroid vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0000118 - multiseptate vegetative cell

References:

Genotypes:

FYPO:0001368 - normal actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0007689 - normal cell growth polarization

References:

Genotypes:

FYPO:0001587 - normal protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0001120 - pear-shaped vegetative cell

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Genotypes:

FYPO:0000107 - sensitive to latrunculin A

References:

Genotypes:

FYPO:0001234 - slow vegetative cell population growth

References:

Genotypes:

FYPO:0000129 - spherical vegetative cell

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Genotypes:

FYPO:0000021 - spheroid vegetative cell

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Genotypes:

FYPO:0000024 - stubby vegetative cell

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Genotypes:

FYPO:0001496 - viable elongated multiseptate vegetative cell

References:

Genotypes:

FYPO:0004256 - viable lemon-shaped cell

References:

Genotypes:

FYPO:0004103 - viable spherical vegetative cell

References:

Genotypes:

FYPO:0002380 - viable spheroid vegetative cell

References:

Genotypes:

FYPO:0007231 - viable spindle-shaped cell

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Genotypes:

FYPO:0002106 - viable stubby vegetative cell

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Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

Qualitative gene expression

PomGeneEx:0000019 - protein level decreased

References:

PomGeneEx:0000018 - protein level increased

References:

PomGeneEx:0000011 - RNA level increased

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Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0000790 - abnormal actin cortical patch organization

References:

Genotypes:

FYPO:0002089 - abnormal exocytosis during vegetative growth

References:

Genotypes:

FYPO:0000054 - abnormal microtubule cytoskeleton organization

References:

Genotypes:

FYPO:0006497 - abnormal plasma membrane phosphatidylserine distribution

References:

Genotypes:

FYPO:0000443 - abnormal protein localization during vegetative growth

References:

Genotypes:

FYPO:0000742 - abnormal protein localization to actin cortical patch

References:

Genotypes:

FYPO:0000928 - abnormal protein localization to cell cortex during vegetative growth

References:

Genotypes:

FYPO:0000121 - abnormal sporulation

References:

Genotypes:

FYPO:0002998 - abolished actomyosin contractile ring assembly, clumped medial cortical nodes

References:

Genotypes:

FYPO:0001585 - abolished protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0006447 - abolished protein localization to cleavage furrow during vegetative growth

References:

Genotypes:

FYPO:0000705 - abolished protein-protein interaction

References:

Genotypes:

FYPO:0003315 - actin cables absent from cell

References:

Genotypes:

FYPO:0001394 - activation of monopolar cell growth at either end

References:

Genotypes:

FYPO:0000016 - curved vegetative cell

References:

Genotypes:

FYPO:0000082 - decreased cell population growth at high temperature

References:

Genotypes:

FYPO:0000080 - decreased cell population growth at low temperature

References:

Genotypes:

FYPO:0001407 - decreased cell population growth on glucose carbon source

References:

Genotypes:

FYPO:0009053 - decreased cell population growth on glutamate nitrogen source

References:

Genotypes:

FYPO:0000684 - decreased cell population growth on glycerol carbon source

References:

Genotypes:

FYPO:0009091 - decreased cell population growth on lysine and proline nitrogen source

References:

Genotypes:

FYPO:0002924 - decreased cell population growth on maltose carbon source

References:

Genotypes:

FYPO:0001586 - decreased protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0001365 - decreased rate of actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0003014 - decreased rate of actomyosin contractile ring disassembly

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0002021 - dispersed actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0002655 - enlarged exocytic vesicles present in increased numbers

References:

Genotypes:

FYPO:0003938 - increased cell population growth during glucose starvation

References:

Genotypes:

FYPO:0009077 - increased cell population growth on ethanol carbon source

References:

Genotypes:

FYPO:0005261 - increased cell population growth on galactose carbon source

References:

Genotypes:

FYPO:0004167 - increased cell population growth on glycerol carbon source

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Genotypes:

FYPO:0009098 - increased cell population growth on mannitol carbon source

References:

Genotypes:

FYPO:0009096 - increased cell population growth on xylose carbon source

References:

Genotypes:

FYPO:0004557 - increased vegetative cell population growth

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0000224 - lemon-shaped cell

References:

Genotypes:

FYPO:0000245 - loss of viability in stationary phase

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Genotypes:

FYPO:0002401 - microtubule bundles present in increased numbers

References:

Genotypes:

FYPO:0001368 - normal actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0001367 - normal cytokinesis

References:

Genotypes:

FYPO:0007708 - normal dynamic protein localization to cell tip

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Genotypes:

FYPO:0000426 - normal endocytosis

References:

Genotypes:

FYPO:0001164 - normal growth on glucose carbon source

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Genotypes:

FYPO:0002619 - normal growth on sodium butyrate

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Genotypes:

FYPO:0000644 - normal protein localization during vegetative growth

References:

Genotypes:

FYPO:0007451 - normal protein localization to cell cortex of cell tip during vegetative growth

References:

Genotypes:

FYPO:0002442 - normal protein localization to cell division site

References:

Genotypes:

FYPO:0001587 - normal protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0002999 - normal protein localization to medial cortical node

References:

Genotypes:

FYPO:0008003 - normal protein localization to site of mechanical stress

References:

Genotypes:

FYPO:0000703 - normal protein-protein interaction

References:

Genotypes:

FYPO:0003193 - normal rate of microtubule depolymerization during vegetative growth

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Genotypes:

FYPO:0003225 - normal rate of microtubule polymerization during vegetative growth

References:

Genotypes:

FYPO:0005806 - normal rate of protein movement within plasma membrane at cell side

References:

Genotypes:

FYPO:0005805 - normal rate of protein movement within plasma membrane at cell tip

References:

Genotypes:

FYPO:0001315 - normal vegetative cell morphology

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0002445 - protein mislocalized to actin cortical patch

References:

Genotypes:

FYPO:0004730 - protein mislocalized to lateral cell cortex

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Genotypes:

FYPO:0000551 - pseudohyphal growth abolished

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Genotypes:

FYPO:0009036 - resistance to benzamidine

References:

Genotypes:

FYPO:0000067 - resistance to brefeldin A

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Genotypes:

FYPO:0009038 - resistance to egtazic acid

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Genotypes:

FYPO:0009034 - resistance to ethylenediaminetetraacetic acid

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Genotypes:

FYPO:0004513 - resistance to latrunculin A

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Genotypes:

FYPO:0001583 - resistance to lithium

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Genotypes:

FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0009040 - resistance to tea tree oil

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Genotypes:

FYPO:0003383 - resistance to tert-butyl hydroperoxide

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Genotypes:

FYPO:0001034 - resistance to tunicamycin

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Genotypes:

FYPO:0000830 - resistance to vanadate

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Genotypes:

FYPO:0007933 - sensitive to 2,2′-dipyridyl

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Genotypes:

FYPO:0001097 - sensitive to amitrole

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Genotypes:

FYPO:0009067 - sensitive to amorolfine

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Genotypes:

FYPO:0007921 - sensitive to benzamidine

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Genotypes:

FYPO:0001701 - sensitive to bortezomib

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Genotypes:

FYPO:0000096 - sensitive to cadmium

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Genotypes:

FYPO:0009080 - sensitive to calcofluor and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0001188 - sensitive to Calcofluor White

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Genotypes:

FYPO:0000085 - sensitive to camptothecin

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Genotypes:

FYPO:0000104 - sensitive to cycloheximide

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Genotypes:

FYPO:0000799 - sensitive to diamide

References:

Genotypes:

FYPO:0007931 - sensitive to egtazic acid

References:

Genotypes:

FYPO:0000842 - sensitive to ethanol during vegetative growth

References:

Genotypes:

FYPO:0000785 - sensitive to formamide

References:

Genotypes:

FYPO:0000087 - sensitive to hydrogen peroxide

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Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

References:

Genotypes:

FYPO:0000107 - sensitive to latrunculin A

References:

Genotypes:

FYPO:0001719 - sensitive to lithium

References:

Genotypes:

FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

References:

Genotypes:

FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0006836 - sensitive to magnesium chloride

References:

Genotypes:

FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0000089 - sensitive to methyl methanesulfonate

References:

Genotypes:

FYPO:0001214 - sensitive to potassium chloride

References:

Genotypes:

FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

References:

Genotypes:

FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0005889 - sensitive to sodium chloride

References:

Genotypes:

FYPO:0009090 - sensitive to sodium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0000841 - sensitive to sodium dodecyl sulfate

References:

Genotypes:

FYPO:0002328 - sensitive to terbinafine

References:

Genotypes:

FYPO:0002701 - sensitive to torin1

References:

Genotypes:

FYPO:0002546 - sensitive to trichostatin A

References:

Genotypes:

FYPO:0000115 - sensitive to valproic acid

References:

Genotypes:

FYPO:0001234 - slow vegetative cell population growth

References:

Genotypes:

FYPO:0000024 - stubby vegetative cell

References:

Genotypes:

FYPO:0002941 - swollen spheroid cell

References:

Genotypes:

FYPO:0004103 - viable spherical vegetative cell

References:

Genotypes:

FYPO:0002106 - viable stubby vegetative cell

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0000055 - no apparent S. cerevisiae ortholog

Protein features

IDNameInterPro nameDB name
PF02181FH2FH2_ForminPfam
PF06367Drf_FH3FH3_domPfam
PS51232GBD_FH3GBD/FH3_domPROSITE profiles
PS51444FH2FH2_ForminPROSITE profiles
SM00498FH2FH2_ForminSMART
SM01139Drf_FH3FH3_domSMART
SM01140Drf_GBDGTPase-bdSMART
G3DSA:1.20.58.2220:FF:000006CATH-FunFam
G3DSA:1.20.58.2220FH2_Formin_sfCATH-Gene3D
G3DSA:1.25.10.10ARM-likeCATH-Gene3D
SSF101447SUPERFAMILY
SSF48371ARM-type_foldSUPERFAMILY
PTHR47102Actin_filament_regulatorPANTHER
CoilCOILS
mobidb-lite-Disorderdisorder_predictionMobiDB-Disorder
mobidb-lite-Low-complexitydisorder_predictionMobiDB-Low-complexity
mobidb-lite-Polardisorder_predictionMobiDB-Polar
mobidb-lite-Polyampholytedisorder_predictionMobiDB-Polyampholyte
mobidb-lite-Proline-richdisorder_predictionMobiDB-Proline-rich

Orthologs

References / Literature

PMID:16141239 - Endocytosis in fission yeast is spatially associated with the actin cytoskeleton during polarised cell growth and cytokinesis.
Gachet Y et al. J Cell Sci 2005 Sep 15;118(Pt 18):4231-42
PMID:19542312 - Functional genomics of adhesion, invasion, and mycelial formation in Schizosaccharomyces pombe.
Dodgson J et al. Eukaryot Cell 2009 Aug;8(8):1298-306
PMID:23041194 - Plasma membrane tethering of the cortical ER necessitates its finely reticulated architecture.
Zhang D et al. Curr Biol 2012 Nov 06;22(21):2048-52
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:24554432 - The Tea4-PP1 landmark promotes local growth by dual Cdc42 GEF recruitment and GAP exclusion.
Kokkoris K et al. J Cell Sci 2014 May 01;127(Pt 9):2005-16
PMID:21504829 - Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.
Stewart EV et al. Mol Cell 2011 Apr 22;42(2):160-71
PMID:29996109 - Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.
Swaffer MP et al. Cell Rep 2018 Jul 10;24(2):503-514
PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.
Mata J et al. Nat Genet 2002 Sep;32(1):143-7
PMID:18060866 - ADP-ribosylation factor arf6p may function as a molecular switch of new end take off in fission yeast.
Fujita A Biochem Biophys Res Commun 2008 Feb 01;366(1):193-8
PMID:25422470 - Oscillatory AAA+ ATPase Knk1 constitutes a novel morphogenetic pathway in fission yeast.
Scheffler K et al. Proc Natl Acad Sci U S A 2014 Dec 16;111(50):17899-904
PMID:25825517 - A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast.
Dudin O et al. J Cell Biol 2015 Mar 30;208(7):897-911
PMID:34613787 - Counting actin in contractile rings reveals novel contributions of cofilin and type II myosins to fission yeast cytokinesis.
Malla M et al. Mol Biol Cell 2022 May 15;33(6):ar51
PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.
Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
PMID:25411334 - The Rho-GEF Gef3 interacts with the septin complex and activates the GTPase Rho4 during fission yeast cytokinesis.
Wang N et al. Mol Biol Cell 2015 Jan 15;26(2):238-55
PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323
PMID:19710424 - Pob1 participates in the Cdc42 regulation of fission yeast actin cytoskeleton.
Rincón SA et al. Mol Biol Cell 2009 Oct;20(20):4390-9
PMID:22907753 - Posttranscriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in Schizosaccharomyces pombe.
Wells ML et al. Mol Cell Biol 2012 Oct;32(20):4206-14
PMID:35673994 - Actin assembly requirements of the formin Fus1 to build the fusion focus.
Billault-Chaumartin I et al. J Cell Sci 2022 Jul 01;135(13)
PMID:26960792 - Rga6 is a Fission Yeast Rho GAP Involved in Cdc42 Regulation of Polarized Growth.
Revilla-Guarinos MT et al. Mol Biol Cell 2016 Mar 09;27(9):1524-35
PMID:29290560 - ER-PM Contacts Restrict Exocytic Sites for Polarized Morphogenesis.
Ng AYE et al. Curr Biol 2018 Jan 08;28(1):146-153.e5
PMID:30318352 - A Positive Feedback between Growth and Polarity Provides Directional Persistency and Flexibility to the Process of Tip Growth.
Haupt A et al. Curr Biol 2018 Oct 22;28(20):3342-3351.e3
PMID:21899677 - Cdc42 regulates multiple membrane traffic events in fission yeast.
Estravís M et al. Traffic 2011 Dec;12(12):1744-58
PMID:33496728 - Molecular organization of cytokinesis node predicts the constriction rate of the contractile ring.
Bellingham-Johnstun K et al. J Cell Biol 2021 Mar 01;220(3)
PMID:15184402 - Regulation of a formin complex by the microtubule plus end protein tea1p.
Feierbach B et al. J Cell Biol 2004 Jun 07;165(5):697-707
PMID:23185032 - Nonmedially assembled F-actin cables incorporate into the actomyosin ring in fission yeast.
Huang J et al. J Cell Biol 2012 Nov 26;199(5):831-47
PMID:24947517 - The putative exchange factor Gef3p interacts with Rho3p GTPase and the septin ring during cytokinesis in fission yeast.
Muñoz S et al. J Biol Chem 2014 Aug 08;289(32):21995-2007
PMID:11696322 - Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division.
Feierbach B et al. Curr Biol 2001 Oct 30;11(21):1656-65
PMID:15743909 - Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast.
Kovar DR et al. Mol Biol Cell 2005 May;16(5):2313-24
PMID:19646873 - The conserved NDR kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42.
Das M et al. Curr Biol 2009 Aug 11;19(15):1314-9
GO_REF:0000002 - Comments
PMID:23051734 - Myosin Vs organize actin cables in fission yeast.
Lo Presti L et al. Mol Biol Cell 2012 Dec;23(23):4579-91
PMID:12415007 - The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast.
Nakano K et al. J Cell Sci 2002 Dec 01;115(Pt 23):4629-39
PMID:22137473 - Shaping fission yeast cells by rerouting actin-based transport on microtubules.
Lo Presti L et al. Curr Biol 2011 Dec 20;21(24):2064-9
PMID:25963819 - Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly.
Lucena R et al. J Cell Biol 2015 May 11;209(3):387-402
PMID:23861937 - Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast.
Zhang L et al. PLoS One 2013;8(7):e68738
PMID:39012625 - Arp2/3-dependent endocytosis ensures Cdc42 oscillations by removing Pak1-mediated negative feedback.
Harrell MA et al. J Cell Biol 2024 Sep 02;223(10)
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:23695164 - Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.
Das J et al. Sci Signal 2013 May 21;6(276):ra38
PMID:22891673 - Fission yeast sec3 bridges the exocyst complex to the actin cytoskeleton.
Jourdain I et al. Traffic 2012 Nov;13(11):1481-95
PMID:29259000 - Genes Important for Schizosaccharomyces pombe Meiosis Identified Through a Functional Genomics Screen.
Blyth J et al. Genetics 2018 Feb;208(2):589-603
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:25837586 - Spontaneous Cdc42 polarization independent of GDI-mediated extraction and actin-based trafficking.
Bendezú FO et al. PLoS Biol 2015 Apr;13(4):e1002097
PMID:39476757 - Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.
Cipak L et al. Biochem Biophys Res Commun 2024 Oct 25;736:150895
PMID:34666001 - Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast.
Neeli-Venkata R et al. Dev Cell 2021 Oct 25;56(20):2856-2870.e7
PMID:17085965 - Function of rax2p in the polarized growth of fission yeast.
Choi E et al. Mol Cells 2006 Oct 31;22(2):146-53
PMID:22505610 - Cylindrical cellular geometry ensures fidelity of division site placement in fission yeast.
Mishra M et al. J Cell Sci 2012 Aug 15;125(Pt 16):3850-7
PMID:22891259 - Fission yeast Ags1 confers the essential septum strength needed for safe gradual cell abscission.
Cortés JC et al. J Cell Biol 2012 Aug 20;198(4):637-56
PMID:27918601 - Identifying genes required for respiratory growth of fission yeast.
Malecki M et al. Wellcome Open Res 2016;1:12
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:12214236 - Actin dynamics in the contractile ring during cytokinesis in fission yeast.
Pelham RJ et al. Nature 2002 Sep 05;419(6902):82-6
PMID:19264558 - Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.
Deshpande GP et al. DNA Repair (Amst) 2009 May 01;8(5):672-9
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:24146635 - Hsp70-Hsp40 chaperone complex functions in controlling polarized growth by repressing Hsf1-driven heat stress-associated transcription.
Vjestica A et al. PLoS Genet 2013;9(10):e1003886
PMID:16866873 - Actin-capping protein is involved in controlling organization of actin cytoskeleton together with ADF/cofilin, profilin and F-actin crosslinking proteins in fission yeast.
Nakano K et al. Genes Cells 2006 Aug;11(8):893-905
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.
Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:20362451 - Electrical control of cell polarization in the fission yeast Schizosaccharomyces pombe.
Minc N et al. Curr Biol 2010 Apr 27;20(8):710-6
PMID:17377067 - Regulation of cell diameter, For3p localization, and cell symmetry by fission yeast Rho-GAP Rga4p.
Das M et al. Mol Biol Cell 2007 Jun;18(6):2090-101
PMID:30044717 - Roles of the fission yeast UNC-13/Munc13 protein Ync13 in late stages of cytokinesis.
Zhu YH et al. Mol Biol Cell 2018 Sep 15;29(19):2259-2279
PMID:21652630 - Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.
Snaith HA et al. J Cell Sci 2011 Jul 01;124(Pt 13):2187-99
PMID:26941334 - Unique spatiotemporal activation pattern of Cdc42 by Gef1 and Scd1 promotes different events during cytokinesis.
Wei B et al. Mol Biol Cell 2016 Apr 15;27(8):1235-45
PMID:15809031 - Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity.
Martin SG et al. Dev Cell 2005 Apr;8(4):479-91
PMID:22768263 - Fission yeast Sec3 and Exo70 are transported on actin cables and localize the exocyst complex to cell poles.
Bendezú FO et al. PLoS One 2012;7(6):e40248
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
PMID:31495586 - Capping Protein Insulates Arp2/3-Assembled Actin Patches from Formins.
Billault-Chaumartin I et al. Curr Biol 2019 Oct 07;29(19):3165-3176.e6
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:19474789 - A spatial gradient coordinates cell size and mitotic entry in fission yeast.
Moseley JB et al. Nature 2009 Jun 11;459(7248):857-60
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
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