PomBase home

protein coding gene - atp9 (SPMIT.10) - F1-FO ATP synthase membrane subunit, Atp9

Gene summary

Standard name
atp9
Systematic ID
SPMIT.10
Product
F1-FO ATP synthase membrane subunit, Atp9
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
P21537
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome Mitochondrial: 17808..18046 forward strand

Annotation

Disease association

MONDO:0859215 - dystonia, early-onset, and/or spastic paraplegia

References:

GO biological process

GO:0042776 - proton motive force-driven mitochondrial ATP synthesis

References:

GO:1902600 - proton transmembrane transport

References:

GO cellular component

GO:0099617 - matrix side of mitochondrial inner membrane

References:

GO:0045259 - proton-transporting ATP synthase complex

References:

GO:0033177 - proton-transporting two-sector ATPase complex, proton-transporting domain

References:

GO molecular function

GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism

References:

Protein sequence feature

SO:0001812 - transmembrane_helix

References:

Qualitative gene expression

PomGeneEx:0000011 - RNA level increased

References:

Quantitative gene expression

PBO:0011963 - RNA level

References:

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF00137ATP-synt_CATPase_proteolipid_c-like_domPfam
cd18182ATP-synt_Fo_c_ATP5G3CDD
PS00605ATPASE_CATP_synth_F0_csu_DDCD_BSPROSITE patterns
PR00124ATPASECATP_synth_F0_csuPRINTS
G3DSA:1.20.20.10:FF:000003CATH-FunFam
G3DSA:1.20.20.10ATP_synth_F0_csu_sfCATH-Gene3D
SSF81333F/V-ATP_Csub_sfSUPERFAMILY
PTHR10031ATP_synth_F0_csuPANTHER
NF005733PRK07558.1NCBIFAM
Transmembrane alpha helixDeepTMHMM
MF_01396ATP_synth_c_bactATP_synth_F0_csuHAMAP

Orthologs

References / Literature

PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:39289458 - Characterization of Shy1, the Schizosaccharomyces pombe homolog of human SURF1.
Luo Y et al. Sci Rep 2024 Sep 17;14(1):21678
PMID:26896847 - Ensembl comparative genomics resources.
Herrero J et al. Database (Oxford) 2016;2016
PMID:21727087 - A genome wide study in fission yeast reveals nine PPR proteins that regulate mitochondrial gene expression.
Kühl I et al. Nucleic Acids Res 2011 Oct;39(18):8029-41
PMID:11152613 - Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
Krogh A et al. J Mol Biol 2001 Jan 19;305(3):567-80
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
PMID:17135288 - Prohibitins interact genetically with Atp23, a novel processing peptidase and chaperone for the F1Fo-ATP synthase.
Osman C et al. Mol Biol Cell 2007 Feb;18(2):627-35
PMID:40427588 - The Insertion Domain of Mti2 Facilitates the Association of Mitochondrial Initiation Factors with Mitoribosomes in Schizosaccharomyces pombe .
Luo Y et al. Biomolecules 2025 May 10;15(5)
GO_REF:0000002 - Comments
PMID:28334955 - The Schizosaccharomyces pombe PPR protein Ppr10 associates with a novel protein Mpa1 and acts as a mitochondrial translational activator.
Wang Y et al. Nucleic Acids Res 2017 Apr 07;45(6):3323-3340
PMID:33049028 - Schizosaccharomyces pombe Ppr10 is required for mitochondrial translation.
Liu Z et al. FEMS Microbiol Lett 2020 Oct 21;367(19)
PMID:31364709 - Intraspecific Diversity of Fission Yeast Mitochondrial Genomes.
Tao YT et al. Genome Biol Evol 2019 Aug 01;11(8):2312-2329
PMID:38499152 - Sls1 and Mtf2 mediate the assembly of the Mrh5C complex required for activation of cox1 mRNA translation.
Wang Y et al. J Biol Chem 2024 Mar 16;:107176
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:38269097 - Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology.
Morozumi Y et al. iScience 2024 Jan 19;27(1):108777
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.
Mata J et al. Nat Genet 2002 Sep;32(1):143-7
GO_REF:0000033 - Annotation inferences using phylogenetic trees