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lncRNA gene - fbp1-ot2 (SPNCRNA.1326) - fbp1 upstream regulatory lncRNA b

Gene summary

Standard name
fbp1-ot2
Systematic ID
SPNCRNA.1326
Product
fbp1 upstream regulatory lncRNA b
Organism
Schizosaccharomyces pombe (fission yeast)
Feature type
lncRNA gene
Genomic location
chromosome II: 197660..201812 reverse strand

Annotation

GO biological process

GO:0010628 - positive regulation of gene expression

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Multi-locus phenotype

FYPO:0010065 - decreased nucleosome occupancy at transcription regulatory region

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Genotypes:

FYPO:0010066 - decreased transcription regulatory region sequence-specific DNA binding during cellular response to glucose starvation

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Genotypes:

FYPO:0004171 - normal RNA level during glucose starvation

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Quantitative gene expression

PBO:0011963 - RNA level

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Single locus phenotype

FYPO:0007808 - resistance to valproic acid

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Genotypes:

FYPO:0000095 - sensitive to bleomycin

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Genotypes:

References / Literature

PMID:41916008 - The RNA molecule or the transcription process: which is critical in the regulation of fbp1 gene activation mediated by metabolic stress-induced lncRNA (mlonRNA) in fission yeast.
Oe H et al. Biochem Biophys Res Commun 2026 Mar 26;815:153674
PMID:18820678 - Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs.
Hirota K et al. Nature 2008 Nov 06;456(7218):130-4
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:29914874 - Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast.
Atkinson SR et al. RNA 2018 Sep;24(9):1195-1213
PMID:34984977 - Functional profiling of long intergenic non-coding RNAs in fission yeast.
Rodriguez-Lopez M et al. Elife 2022 Jan 05;11