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lncRNA gene - nam1 (SPNCRNA.1459) - cis-acting regulatory lncRNA nam1, byr2 repressing

Gene summary

Standard name
nam1
Systematic ID
SPNCRNA.1459
Product
cis-acting regulatory lncRNA nam1, byr2 repressing
Organism
Schizosaccharomyces pombe (fission yeast)
Feature type
lncRNA gene
Genomic location
chromosome II: 1742555..1744043 reverse strand

Annotation

Quantitative gene expression

PBO:0011963 - RNA level

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Single locus phenotype

FYPO:0002133 - abolished protein-RNA interaction

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Genotypes:

FYPO:0000303 - decreased conjugation frequency

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Genotypes:

FYPO:0001283 - decreased protein level during cellular response to nitrogen starvation

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Genotypes:

FYPO:0001152 - decreased RNA level during nitrogen starvation

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Genotypes:

FYPO:0006548 - increased gene expression

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Genotypes:

FYPO:0001147 - normal mating efficiency

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Genotypes:

References / Literature

PMID:32415063 - Conserved protein Pir2 ARS2 mediates gene repression through cryptic introns in lncRNAs.
Thillainadesan G et al. Nat Commun 2020 May 15;11(1):2412
PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.
Skribbe M et al. Mol Cell 2025 Feb 19;
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:28765164 - Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation.
Touat-Todeschini L et al. EMBO J 2017 Sep 01;36(17):2626-2641
PMID:29914874 - Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast.
Atkinson SR et al. RNA 2018 Sep;24(9):1195-1213
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6