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lncRNA gene - nc-tgp1 (SPNCRNA.1698) - tgp1 sense interfering RNA

Gene summary

Standard name
nc-tgp1
Systematic ID
SPNCRNA.1698
Product
tgp1 sense interfering RNA
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
INT_0_2957
Feature type
lncRNA gene
Genomic location
chromosome II: 352335..354234 reverse strand

Annotation

GO biological process

GO:0030643 - intracellular phosphate ion homeostasis

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GO:0060633 - negative regulation of transcription initiation by RNA polymerase II

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Multi-locus phenotype

FYPO:0007409 - abnormal mRNA alternative polyadenylation

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Genotypes:

Qualitative gene expression

PomGeneEx:0000012 - RNA level decreased

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Single locus phenotype

FYPO:0007409 - abnormal mRNA alternative polyadenylation

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Genotypes:

FYPO:0007407 - increased level of phosphate starvation gene mRNA during vegetative growth

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Genotypes:

FYPO:0000825 - increased RNA level during vegetative growth

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Genotypes:

FYPO:0006614 - increased termination of RNA polymerase II transcription

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Genotypes:

FYPO:0001317 - normal RNA level during vegetative growth

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Genotypes:

FYPO:0000097 - sensitive to caffeine during vegetative growth

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Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

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Genotypes:

FYPO:0000091 - sensitive to thiabendazole

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Genotypes:

References / Literature

PMID:25428589 - Long non-coding RNA-mediated transcriptional interference of a permease gene confers drug tolerance in fission yeast.
Ard R et al. Nat Commun 2014 Nov 27;5:5576
PMID:32499400 - Nutrient-dependent control of RNA polymerase II elongation rate regulates specific gene expression programs by alternative polyadenylation.
Yague-Sanz C et al. Genes Dev 2020 Jul 01;34(13-14):883-897
PMID:34389684 - Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1.
Schwer B et al. Proc Natl Acad Sci U S A 2021 Aug 17;118(33)
PMID:36794724 - Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis.
Garg A et al. Nucleic Acids Res 2023 Apr 24;51(7):3094-3115