snRNA gene - snu4 (SPSNRNA.04) - small nuclear RNA U4

Gene summary

Standard name

snu4

Systematic ID

SPSNRNA.04

Product

small nuclear RNA U4

Organism

Schizosaccharomyces pombe (fission yeast)

Synonyms

prp13

Feature type

snRNA gene

Genomic location

chromosome II: 467489..467615 reverse strand

Annotation

References / Literature

PMID:7616961 - Rescue of the fission yeast snRNA synthesis mutant snm1 by overexpression of the double-strand-specific Pac1 ribonuclease.

Rotondo G et al. Mol Gen Genet 1995 Jun 25;247(6):698-708

PMID:9003295 - Isolation of novel pre-mRNA splicing mutants of Schizosaccharomyces pombe.

Urushiyama S et al. Mol Gen Genet 1996 Nov 27;253(1-2):118-27

PMID:24298023 - Characterization and in vivo functional analysis of the Schizosaccharomyces pombe ICLN gene.

Barbarossa A et al. Mol Cell Biol 2014 Feb;34(4):595-605

PMID:17284461 - Biochemical and genetic analysis of RNA cap guanine-N2 methyltransferases from Giardia lamblia and Schizosaccharomyces pombe.

Hausmann S et al. Nucleic Acids Res 2007;35(5):1411-20

PMID:2795654 - Schizosaccharomyces pombe U4 small nuclear RNA closely resembles vertebrate U4 and is required for growth.

Dandekar T et al. J Mol Biol 1989 Aug 05;208(3):371-9

PMID:2144896 - Immunoprecipitation distinguishes non-overlapping groups of snRNPs in Schizosaccharomyces pombe.

Tollervey D et al. Nucleic Acids Res 1990 Sep 11;18(17):5207-12

PMID:8809017 - Localization of modified nucleotides in Schizosaccharomyces pombe spliceosomal small nuclear RNAs: modified nucleotides are clustered in functionally important regions.

Gu J et al. RNA 1996 Sep;2(9):909-18

PMID:2806913 - Cloning of Schizosaccharomyces pombe genes encoding the U1, U2, U3 and U4 snRNAs.

Dandekar T et al. Gene 1989 Sep 30;81(2):227-35

PMID:2953599 - Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs.

Tollervey D et al. EMBO J 1987 Feb;6(2):469-76

PMID:2406130 - A mutation in a single gene of Schizosaccharomyces pombe affects the expression of several snRNAs and causes defects in RNA processing.

Potashkin J et al. EMBO J 1990 Feb;9(2):525-34

PMID:28765164 - Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation.

Touat-Todeschini L et al. EMBO J 2017 Sep 01;36(17):2626-2641

PMID:20400941 - Specific splicing defects in S. pombe carrying a degron allele of the Survival of Motor Neuron gene.

Campion Y et al. EMBO J 2010 Jun 02;29(11):1817-29

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:20018856 - Involvement of the spliceosomal U4 small nuclear RNA in heterochromatic gene silencing at fission yeast centromeres.

Chinen M et al. J Biol Chem 2010 Feb 19;285(8):5630-8

PMID:1441744 - Mutational analysis of Schizosaccharomyces pombe U4 snRNA by plasmid exchange.

Dandekar T et al. Yeast 1992 Aug;8(8):647-53

PMID:34352089 - Co-transcriptional RNA cleavage by Drosha homolog Pac1 triggers transcription termination in fission yeast.

Yague-Sanz C et al. Nucleic Acids Res 2021 Sep 07;49(15):8610-8624

PMID:28231281 - The intron in centromeric noncoding RNA facilitates RNAi-mediated formation of heterochromatin.

Mutazono M et al. PLoS Genet 2017 Feb;13(2):e1006606

GO_REF:0000051 - S. pombe keyword mapping

PMID:10445882 - Pac1p, an RNase III homolog, is required for formation of the 3' end of U2 snRNA in Schizosaccharomyces pombe.

Zhou D et al. RNA 1999 Aug;5(8):1083-98

PMID:2192258 - Differential distribution of factors involved in pre-mRNA processing in the yeast cell nucleus.

Potashkin JA et al. Mol Cell Biol 1990 Jul;10(7):3524-34