snRNA gene - snu6 (SPSNRNA.06) - small nuclear RNA U6

Gene summary

Standard name

snu6

Systematic ID

SPSNRNA.06

Product

small nuclear RNA U6

Organism

Schizosaccharomyces pombe (fission yeast)

Synonyms

U6snRNA, U6

Feature type

snRNA gene

Genomic location

chromosome I: 2562276..2562419 reverse strand

Annotation

References / Literature

PMID:11842100 - The Schizosaccharomyces pombe mgU6-47 gene is required for 2'-O-methylation of U6 snRNA at A41.

Zhou H et al. Nucleic Acids Res 2002 Feb 15;30(4):894-902

PMID:22064476 - A U1-U2 snRNP interaction network during intron definition.

Shao W et al. Mol Cell Biol 2012 Jan;32(2):470-8

PMID:35277511 - The methyl phosphate capping enzyme Bmc1/Bin3 is a stable component of the fission yeast telomerase holoenzyme.

Porat J et al. Nat Commun 2022 Mar 11;13(1):1277

PMID:9001235 - Severe growth defect in a Schizosaccharomyces pombe mutant defective in intron lariat degradation.

Nam K et al. Mol Cell Biol 1997 Feb;17(2):809-18

PMID:9745017 - Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutants.

Potashkin J et al. Curr Genet 1998 Sep;34(3):153-63

PMID:12374752 - Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23).

Huang T et al. EMBO J 2002 Oct 15;21(20):5516-26

PMID:32518066 - Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes.

Montemayor EJ et al. RNA 2020 Oct;26(10):1400-1413

PMID:2336389 - Schizosaccharomyces U6 genes have a sequence within their introns that matches the B box consensus of tRNA internal promoters.

Frendewey D et al. Nucleic Acids Res 1990 Apr 25;18(8):2025-32

PMID:2798130 - Splicing of the U6 RNA precursor is impaired in fission yeast pre-mRNA splicing mutants.

Potashkin J et al. Nucleic Acids Res 1989 Oct 11;17(19):7821-31

GO_REF:0000115 - Automatic Gene Ontology annotation of non-coding RNA sequences through association of Rfam records with GO terms

PMID:1620594 - Activity of chimeric RNAs of U6 snRNA and (-)sTRSV in the cleavage of a substrate RNA.

Tani T et al. Nucleic Acids Res 1992 Jun 25;20(12):2991-6

PMID:2909894 - The gene for the U6 small nuclear RNA in fission yeast has an intron.

Tani T et al. Nature 1989 Jan 05;337(6202):87-90

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:2398900 - Evolutionary origin of the U6 small nuclear RNA intron.

Reich C et al. Mol Cell Biol 1990 Oct;10(10):5548-52

PMID:2795654 - Schizosaccharomyces pombe U4 small nuclear RNA closely resembles vertebrate U4 and is required for growth.

Dandekar T et al. J Mol Biol 1989 Aug 05;208(3):371-9

PMID:2299673 - An intron-containing Schizosaccharomyces pombe U6 RNA gene can be transcribed by human RNA polymerase III.

Kleinschmidt AM et al. J Mol Biol 1990 Jan 05;211(1):7-9

PMID:31294478 - Senataxin homologue Sen1 is required for efficient termination of RNA polymerase III transcription.

Rivosecchi J et al. EMBO J 2019 Aug 15;38(16):e101955

PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.

Skribbe M et al. Mol Cell 2025 Feb 19;

PMID:10409726 - Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing.

McDonald WH et al. Mol Cell Biol 1999 Aug;19(8):5352-62

PMID:2044950 - mRNA-type introns in U6 small nuclear RNA genes: implications for the catalysis in pre-mRNA splicing.

Tani T et al. Genes Dev 1991 Jun;5(6):1022-31

PMID:23022480 - Mpn1, mutated in poikiloderma with neutropenia protein 1, is a conserved 3'-to-5' RNA exonuclease processing U6 small nuclear RNA.

Shchepachev V et al. Cell Rep 2012 Oct 25;2(4):855-65

PMID:25263959 - Structural and functional insights into the N-terminus of Schizosaccharomyces pombe Cdc5.

Collier SE et al. Biochemistry 2014 Oct 21;53(41):6439-51

PMID:2144896 - Immunoprecipitation distinguishes non-overlapping groups of snRNPs in Schizosaccharomyces pombe.

Tollervey D et al. Nucleic Acids Res 1990 Sep 11;18(17):5207-12

GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.

PMID:37403782 - The fission yeast methyl phosphate capping enzyme Bmc1 guides 2'-O-methylation of the U6 snRNA.

Porat J et al. Nucleic Acids Res 2023 Sep 08;51(16):8805-8819

PMID:23754748 - Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly.

Banerjee S et al. Mol Cell Biol 2013 Aug;33(16):3125-36

PMID:28525753 - The U6 snRNA m 6 A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.

Pendleton KE et al. Cell 2017 May 18;169(5):824-835.e14

PMID:2192258 - Differential distribution of factors involved in pre-mRNA processing in the yeast cell nucleus.

Potashkin JA et al. Mol Cell Biol 1990 Jul;10(7):3524-34

PMID:8809017 - Localization of modified nucleotides in Schizosaccharomyces pombe spliceosomal small nuclear RNAs: modified nucleotides are clustered in functionally important regions.

Gu J et al. RNA 1996 Sep;2(9):909-18