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Haploid genotype - adf1-1(L57S aa)

Genotype summary

Description
adf1-1(L57S aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
adf1 (SPAC20G4.06c)actin depolymerizing factor, cofilinadf1-1L57Samino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0002031 - abnormal actin cable morphology

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FYPO:0000161 - abnormal actomyosin contractile ring assembly

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FYPO:0003338 - abnormal actomyosin contractile ring morphology

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FYPO:0002998 - abolished actomyosin contractile ring assembly, clumped medial cortical nodes

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FYPO:0003371 - abolished protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm

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FYPO:0007200 - aggregated actin cortical patches during mitotic interphase

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FYPO:0005430 - aggregated actin cortical patches during vegetative growth

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FYPO:0006029 - decreased actin filament depolymerization

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FYPO:0006207 - decreased rate of actin filament depolymerization

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FYPO:0001365 - decreased rate of actomyosin contractile ring contraction

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FYPO:0000745 - delayed onset of actin cortical patch internalization

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0004652 - normal actomyosin contractile ring morphology

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FYPO:0002999 - normal protein localization to medial cortical node

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0001904 - premature actomyosin contractile ring disassembly

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FYPO:0002060 - viable vegetative cell population

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