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Haploid genotype - adf1-M3(E132A,K133A aa)

Genotype summary

Description
adf1-M3(E132A,K133A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
adf1 (SPAC20G4.06c)actin depolymerizing factor, cofilinadf1-M3E132A,K133Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000230 - abnormal actomyosin contractile ring actin filament organization

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FYPO:0003338 - abnormal actomyosin contractile ring morphology

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FYPO:0003444 - abnormal medial cortical node condensation

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FYPO:0003838 - abolished actomyosin contractile ring contraction

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FYPO:0002656 - decreased actin filament binding

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FYPO:0006307 - decreased actin filament severing

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FYPO:0003339 - decreased rate of actomyosin contractile ring assembly

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FYPO:0003014 - decreased rate of actomyosin contractile ring disassembly

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0001881 - elongated actin filaments

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FYPO:0003336 - increased duration of protein localization to actomyosin contractile ring

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FYPO:0004854 - increased protein localization to actomyosin contractile ring

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FYPO:0007899 - increased rate of protein localization to actomyosin contractile ring

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FYPO:0006305 - normal actin monomer binding

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FYPO:0004895 - normal rate of actomyosin contractile ring contraction

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FYPO:0001904 - premature actomyosin contractile ring disassembly

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FYPO:0005475 - swollen vegetative cell with normal cell length

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FYPO:0006308 - thick actin cables in medial region

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