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Haploid genotype - ago1delta clr4-IDR-Mut2(K109Q,K110Q,K113Q,K114Q,K122Q,R123Q,R126Q,K127Q aa)

Genotype summary

Description
ago1delta clr4-IDR-Mut2(K109Q,K110Q,K113Q,K114Q,K122Q,R123Q,R126Q,K127Q aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
ago1 (SPCC736.11)argonauteago1deltadeletiondeletionNull
clr4 (SPBC428.08c)histone lysine H3-K9 methyltransferase (Suv39) Clr4clr4-IDR-Mut2K109Q,K110Q,K113Q,K114Q,K122Q,R123Q,R126Q,K127Qamino_acid_mutationNot assayed or wild type

Annotation

Multi-locus phenotype

FYPO:0007334 - abolished chromatin silencing at centromere outer repeat

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FYPO:0007336 - abolished chromatin silencing at silent mating-type cassette

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FYPO:0004745 - abolished histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0006112 - abolished histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth

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FYPO:0003573 - decreased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0010050 - decreased protein localization to heterochromatin at silent mating-type cassette cenH region

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FYPO:0004689 - increased cenH-derived RNA level

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