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Haploid genotype - alp13delta

Genotype summary

Description
alp13delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
alp13 (SPAC23H4.12)Clr6 histone deacetylase complex, chromodomain subunit Alp13/Eaf3alp13deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0007472 - abnormal histone exchange

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FYPO:0000059 - abnormal mitotic cell cycle

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FYPO:0005046 - abnormal mitotic sister chromatid segregation with lagging chromosomes, complete sister chromatid separation, and decreased rate of mitotic spindle elongation

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0007217 - decreased histone H3-K9 acetylation at protein coding gene during vegetative growth

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FYPO:0008183 - decreased histone H3-S10 phosphorylation during vegetative growth

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FYPO:0008224 - decreased histone H4-K20 trimethylation during mitotic G2/M phase

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FYPO:0000470 - decreased mating type switching

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FYPO:0001117 - decreased RNA level during vegetative growth

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0003557 - increased antisense RNA level

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FYPO:0005315 - increased chromatin silencing at centromere central core

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FYPO:0003547 - increased DNA damage during vegetative growth

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FYPO:0005522 - increased forward centromeric outer repeat transcript level

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FYPO:0005518 - increased histone H3-K14 acetylation at protein coding gene during vegetative growth

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FYPO:0005310 - increased histone H3-K14 acetylation during vegetative growth

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FYPO:0008219 - increased histone H3-K56 acetylation in transcribed regions during mitotic G2/M phase

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FYPO:0004347 - increased histone H3-K9 acetylation at protein coding gene during vegetative growth

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FYPO:0000892 - increased histone H3-K9 acetylation during vegetative growth

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FYPO:0000887 - increased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0006987 - increased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth

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FYPO:0006361 - increased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0008220 - increased histone H4-K20 monomethylation in transcribed regions during mitotic G2/M phase

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FYPO:0005309 - increased histone H4-K5 acetylation during vegetative growth

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FYPO:0005308 - increased histone H4-K8 acetylation during vegetative growth

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FYPO:0005523 - increased reverse centromeric outer repeat transcript level

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0008221 - normal histone H3-K56 acetylation during mitotic G2/M phase

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FYPO:0008222 - normal histone H4-K20 monomethylation during mitotic G2/M phase

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FYPO:0005336 - normal level of histone H3 in cell

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FYPO:0000857 - normal nucleosome positioning in euchromatin

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0004325 - sensitive to 5-fluorouracil

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000111 - sensitive to rapamycin

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0005750 - sensitive to Zeocin

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FYPO:0002215 - viable curved elongated vegetative cell

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FYPO:0002060 - viable vegetative cell population

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