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Haploid genotype - alp5-1134(S402N aa)

Genotype summary

Description
alp5-1134(S402N aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
alp5 (SPBP23A10.08)Ino80, NuA4 and Swr1 complex actin-like protein Arp4alp5-1134S402Namino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000640 - abnormal chromatin silencing at centromere central core

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FYPO:0003738 - abnormal mitotic cell cycle arrest with condensed chromosomes

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FYPO:0000326 - abnormal mitotic sister chromatid biorientation

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FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0004700 - bent vegetative cell

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FYPO:0005014 - decreased histone H4-K12 acetylation during vegetative growth

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FYPO:0005012 - decreased histone H4-K5 acetylation during vegetative growth

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FYPO:0005013 - decreased histone H4-K8 acetylation during vegetative growth

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FYPO:0002638 - increased activation of mitotic spindle assembly checkpoint

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FYPO:0001837 - increased duration of protein localization to mitotic spindle pole body

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0002430 - inviable after spore germination, multiple cell divisions

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FYPO:0004626 - inviable curved elongated mononucleate vegetative cell

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0004742 - normal chromatin silencing at centromere outer repeat

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FYPO:0003224 - normal histone H3-K14 acetylation during vegetative growth

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FYPO:0003223 - normal histone H3-K9 acetylation during vegetative growth

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FYPO:0002901 - normal protein localization to kinetochore during vegetative growth

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FYPO:0000327 - resistance to trichostatin A

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