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Haploid genotype - apm1delta

Genotype summary

Description
apm1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
apm1 (SPBP16F5.07)AP-1 adaptor complex mu subunit Apm1apm1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000349 - abnormal Golgi morphology

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FYPO:0000059 - abnormal mitotic cell cycle

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FYPO:0007588 - abolished protein localization to late endosome

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FYPO:0002126 - abolished protein localization to plasma membrane during vegetative growth

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FYPO:0002128 - abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth

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FYPO:0002159 - decreased 1,3-beta-D-glucan synthase activity

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0002321 - decreased cellular ergosterol level

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FYPO:0004572 - decreased exocytosis during vegetative growth

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FYPO:0006637 - decreased protein localization to cell cortex of cell tip, with protein distributed in cortex

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FYPO:0008258 - decreased protein localization to cell surface

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FYPO:0007059 - decreased protein localization to late endosome

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FYPO:0003771 - decreased protein localization to plasma membrane of cell tip during vegetative growth

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FYPO:0001885 - decreased protein phosphorylation during salt stress

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0003279 - excess Golgi cisternae present

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FYPO:0001130 - increased protein localization to nucleus during vegetative growth

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FYPO:0000650 - increased septation index

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FYPO:0001494 - inviable elongated multiseptate vegetative cell

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0006518 - loss of viability in G0

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FYPO:0000426 - normal endocytosis

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0002343 - normal growth on terbinafine

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FYPO:0007676 - normal intracellular sterol transport

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FYPO:0008374 - normal phosphatidylinositol-4-phosphate level in the Golgi

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0008373 - normal protein localization to cell surface during cellular response to salt stress

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FYPO:0005114 - normal protein localization to endosome

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FYPO:0003658 - normal protein localization to Golgi membrane

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0007678 - normal sterol distribution

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FYPO:0007589 - protein mislocalized to endosome

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FYPO:0009032 - resistance to bortezomib

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FYPO:0004325 - sensitive to 5-fluorouracil

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FYPO:0002642 - sensitive to amphotericin B

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FYPO:0002720 - sensitive to beta-glucanase

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FYPO:0000079 - sensitive to caspofungin

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FYPO:0001190 - sensitive to cell wall-degrading enzymes

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FYPO:0002640 - sensitive to clotrimazole

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FYPO:0000106 - sensitive to hygromycin B

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FYPO:0002641 - sensitive to micafungin

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FYPO:0001214 - sensitive to potassium chloride

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FYPO:0002617 - sensitive to sodium butyrate

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FYPO:0000086 - sensitive to tacrolimus

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FYPO:0002328 - sensitive to terbinafine

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FYPO:0002546 - sensitive to trichostatin A

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FYPO:0000115 - sensitive to valproic acid

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FYPO:0002788 - small vacuoles during vegetative growth

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FYPO:0002258 - small vacuoles present in increased numbers

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FYPO:0000647 - vegetative cell lysis

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FYPO:0001492 - viable elongated vegetative cell

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FYPO:0002060 - viable vegetative cell population

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