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Haploid genotype - ark1-as3(L166A,S229A,Q28R,Q176R aa)

Genotype summary

Description
ark1-as3(L166A,S229A,Q28R,Q176R aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
ark1 (SPCC320.13c)Aurora-B kinase Ark1ark1-as3L166A,S229A,Q28R,Q176Ramino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000337 - abnormal mitosis

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FYPO:0005201 - abnormal mitotic cell cycle regulation during cellular response to heat stress

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FYPO:0005206 - abnormal mitotic cell cycle regulation upon nitrogen source shift

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FYPO:0000214 - abnormal mitotic chromosome condensation

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FYPO:0005442 - abnormal telomeric DNA separation

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FYPO:0006302 - abolished intra-arm chromosome contact change during mitosis

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FYPO:0007383 - abolished protein localization to kinetochore during mitotic spindle assembly checkpoint signaling

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FYPO:0005366 - abolished protein phosphorylation during mitosis

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0003286 - decreased mitotic chromosome condensation

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0005300 - decreased protein localization to kinetochore during mitotic spindle assembly checkpoint signaling

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FYPO:0000940 - decreased protein localization to mitotic spindle pole body

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FYPO:0001838 - decreased protein phosphorylation during vegetative growth

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FYPO:0005343 - decreased rate of mitotic spindle elongation during anaphase B

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FYPO:0003970 - incomplete mitotic sister chromatid segregation, with chromatin bridge

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FYPO:0004098 - incomplete mitotic sister chromatid segregation, with phi-shaped DNA mass

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FYPO:0006285 - increased duration of protein localization to telomere during mitotic anaphase B

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FYPO:0000451 - increased protein localization to centromere during vegetative growth

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FYPO:0006267 - increased telomere clustering and tethering at nuclear periphery during mitotic metaphase

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FYPO:0004381 - merotelic kinetochore attachment during mitosis

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FYPO:0004396 - normal mitotic spindle elongation

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FYPO:0005633 - sister kinetochore dissociation in meiotic metaphase I, normal chromosome segregation in meiosis I, and sister chromatid non-disjunction in meiosis II

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FYPO:0001234 - slow vegetative cell population growth

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FYPO:0004683 - unequal nucleolus inheritance

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