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Haploid genotype - asf1-1(C30F,D54N aa)

Genotype summary

Description
asf1-1(C30F,D54N aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
asf1 (SPCC663.05c)histone H3-H4 chaperone Asf1asf1-1C30F,D54Namino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0006993 - decreased chromatin silencing at centromere otr1R

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0003096 - decreased histone H3-K9 methylation at centromere outer repeat during vegetative growth

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FYPO:0000470 - decreased mating type switching

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FYPO:0008151 - decreased nucleosome occupancy at centromeric heterochromatin

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FYPO:0005516 - decreased nucleosome occupancy in euchromatin

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FYPO:0003557 - increased antisense RNA level

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FYPO:0007339 - increased cen-dg RNA level

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FYPO:0004347 - increased histone H3-K9 acetylation at protein coding gene during vegetative growth

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FYPO:0008150 - increased rDNA intergenic repeat RNA level

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FYPO:0005917 - increased subtelomeric heterochromatin RNA level

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000089 - sensitive to methyl methanesulfonate

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