Haploid genotype - brc1delta pku80delta

Genotype summary

Description: brc1delta pku80delta
Organism: Schizosaccharomyces pombe (fission yeast)

Allele summary

gene	Product	Allele name	Description	Type	Expression
brc1 (SPBC582.05c)	BRCT domain protein Brc1	brc1delta	deletion	deletion	Null
pku80 (SPBC543.03c)	Ku domain helicase (human XRCC5 ortholog) Pku80	pku80delta	deletion	deletion	Null

Annotation

Multi-locus phenotype

FYPO:0004709 - increased number of Rad52 foci

References:

PMID:25965521

Genes:

FYPO:0002573 - increased number of Ssb1 foci

References:

PMID:25965521

Genes:

FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

References:

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FYPO:0000089 - sensitive to methyl methanesulfonate

References:

Genes:

FYPO:0000268 - sensitive to UV during vegetative growth

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