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Haploid genotype - cdc10-129(T429A aa)

Genotype summary

Description
cdc10-129(T429A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc10 (SPBC336.12c)DNA-binding transcription factor, MBF transcription factor complex subunit Cdc10cdc10-129T429Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003449 - abnormal cell cycle arrest at mitotic G1/S phase transition

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FYPO:0005097 - abnormal cell cycle arrest in mitotic G1 phase

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FYPO:0000848 - abnormal chromosome morphology during vegetative growth

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FYPO:0001430 - abnormal mitotic cell cycle arrest with unreplicated DNA

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FYPO:0004481 - abolished cell population growth at high temperature

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FYPO:0001093 - abolished chromatin binding

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FYPO:0001018 - abolished NETO

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FYPO:0002044 - abolished premeiotic DNA replication

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FYPO:0001508 - abolished protein localization to chromatin during vegetative growth

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FYPO:0003314 - activation of monopolar cell growth at new end

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FYPO:0000445 - cell cycle arrest in mitotic G1 phase

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0005711 - decreased cyclin B1-CDK1 complex level

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FYPO:0000658 - decreased DNA binding

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FYPO:0005933 - decreased protein level during mitotic G1 phase

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FYPO:0003950 - decreased protein localization to chromatin at replication origin

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FYPO:0004630 - decreased RNA level during meiotic cell cycle

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FYPO:0001117 - decreased RNA level during vegetative growth

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FYPO:0004142 - decreased RNA polymerase II proximal promoter sequence-specific DNA binding

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FYPO:0006544 - decreased transcription during mitosis

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FYPO:0006831 - delayed onset of primary cell septum biogenesis

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FYPO:0005773 - elongated mononucleate aseptate vegetative cell

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FYPO:0007380 - elongated T-shaped vegetative cell

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FYPO:0004189 - increased protein level during cellular response to hydroxyurea

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FYPO:0004108 - increased protein level during mitotic G1 phase

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FYPO:0001327 - increased protein level during vegetative growth

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FYPO:0000839 - inviable elongated mononucleate aseptate cell

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FYPO:0001490 - inviable elongated vegetative cell

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0003988 - mislocalized actin cortical patches during vegetative growth

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FYPO:0001398 - monopolar actin cortical patch localization to either end

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FYPO:0001294 - normal actin cortical patch localization

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FYPO:0001395 - normal activation of monopolar cell growth

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FYPO:0006561 - normal CDK-cyclin complex binding during mitotic G1 phase

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FYPO:0005926 - normal protein level during mitotic G1 phase

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0006876 - normal protein localization to cell cortex of cell tip

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FYPO:0001587 - normal protein localization to cell tip during vegetative growth

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FYPO:0000838 - normal protein localization to nucleus during vegetative growth

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FYPO:0006506 - normal RNA level during mitotic G1 phase

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FYPO:0001317 - normal RNA level during vegetative growth

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FYPO:0006279 - normal termination of RNA polymerase II transcription

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FYPO:0006758 - protein absent from cell during mitotic G1 phase

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FYPO:0004072 - RNA absent from cell during cellular response to pheromone

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FYPO:0006975 - RNA absent from cell during meiotic cell cycle

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FYPO:0006103 - short interphase microtubules

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FYPO:0007379 - T-shaped vegetative cell

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FYPO:0001492 - viable elongated vegetative cell

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