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Haploid genotype - cdc10-V50(H362Y aa) cdc13+(wild type)[Knockdown] cig1delta cig2delta

Genotype summary

Description
cdc10-V50(H362Y aa) cdc13+(wild type)[Knockdown] cig1delta cig2delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc10 (SPBC336.12c)DNA-binding transcription factor, MBF transcription factor complex subunit Cdc10cdc10-V50H362Yamino_acid_mutationNot assayed or wild type
cdc13 (SPBC582.03)G2/M B-type cyclin Cdc13cdc13+wild typewild_typeKnockdown
cig1 (SPCC4E9.02)G1/S-specific B-type cyclin Cig1cig1deltadeletiondeletionNull
cig2 (SPAPB2B4.03)G1/S-specific B-type cyclin Cig2cig2deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0001343 - abnormal mitotic DNA replication

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FYPO:0003485 - abolished DNA synthesis

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0004242 - decreased protein kinase activity during mitotic S phase

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FYPO:0000836 - increased protein level

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FYPO:0003332 - normal protein kinase activity during mitotic interphase

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FYPO:0000840 - normal RNA level

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