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Haploid genotype - cdc12-112(F1355S aa)

Genotype summary

Description
cdc12-112(F1355S aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc12 (SPAC1F5.04c)cytokinetic formin Cdc12cdc12-112F1355Samino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000161 - abnormal actomyosin contractile ring assembly

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FYPO:0002872 - abnormal endoplasmic reticulum localization

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FYPO:0002560 - abnormal protein localization to actomyosin contractile ring

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FYPO:0000731 - abnormal protein localization to medial cortex during vegetative growth

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FYPO:0002023 - abnormal septum morphology during vegetative growth

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FYPO:0003000 - abolished actin filament polymerization

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FYPO:0002998 - abolished actomyosin contractile ring assembly, clumped medial cortical nodes

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FYPO:0004481 - abolished cell population growth at high temperature

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FYPO:0002561 - abolished protein localization to actomyosin contractile ring

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FYPO:0001880 - abolished protein localization to cell division site

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FYPO:0006447 - abolished protein localization to cleavage furrow during vegetative growth

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FYPO:0000272 - abolished septum assembly

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FYPO:0001008 - actomyosin contractile ring absent

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FYPO:0007060 - decreased actin filament depolymerization involved in actomyosin contractile ring assembly

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0001365 - decreased rate of actomyosin contractile ring contraction

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000133 - elongated multinucleate vegetative cell

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FYPO:0005870 - incomplete septum

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FYPO:0002025 - inviable elongated multinucleate vegetative cell with abnormal septum morphology

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FYPO:0001006 - inviable elongated multinucleate vegetative cell with central constriction

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FYPO:0007858 - mitotic DNA re-replication in absence of mitotic spindle

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FYPO:0004652 - normal actomyosin contractile ring morphology

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FYPO:0002141 - normal cell population growth at low temperature

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FYPO:0003876 - normal cytokinesis checkpoint

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FYPO:0001400 - normal interphase microtubules

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FYPO:0002558 - normal protein localization to medial cortex during vegetative growth

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FYPO:0002999 - normal protein localization to medial cortical node

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0003126 - post-anaphase array absent from cell

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FYPO:0001904 - premature actomyosin contractile ring disassembly

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FYPO:0002060 - viable vegetative cell population

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