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Haploid genotype - cdc13+(wild type)[Knockdown]

Genotype summary

Description
cdc13+(wild type)[Knockdown]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc13 (SPBC582.03)G2/M B-type cyclin Cdc13cdc13+wild typewild_typeKnockdown

Annotation

Single locus phenotype

FYPO:0000444 - abnormal mitotic cell cycle arrest with replicated DNA

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FYPO:0001430 - abnormal mitotic cell cycle arrest with unreplicated DNA

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FYPO:0001425 - abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication

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FYPO:0006575 - abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication, with otherwise normal S phase

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FYPO:0004759 - abnormal negative regulation of premeiotic DNA replication initiation resulting in complete rereplication

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FYPO:0001093 - abolished chromatin binding

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FYPO:0003378 - abolished meiosis I

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FYPO:0003379 - abolished meiosis II

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FYPO:0000835 - decreased protein level

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FYPO:0003950 - decreased protein localization to chromatin at replication origin

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FYPO:0001838 - decreased protein phosphorylation during vegetative growth

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FYPO:0004189 - increased protein level during cellular response to hydroxyurea

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FYPO:0006291 - increased protein level during mitotic G2 phase

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FYPO:0004961 - increased protein localization to chromatin at replication origin

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FYPO:0002096 - increased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0002083 - inviable swollen elongated cell with enlarged nucleus

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FYPO:0001221 - normal nucleus:cytoplasm ratio

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0004962 - normal protein localization to chromatin at replication origin

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FYPO:0006290 - normal protein phosphorylation during mitotic S phase during cellular response to hydroxyurea

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