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Haploid genotype - cdc13-117(C379Y aa)

Genotype summary

Description
cdc13-117(C379Y aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc13 (SPBC582.03)G2/M B-type cyclin Cdc13cdc13-117C379Yamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000400 - abnormal cell cycle arrest at mitotic G2/M phase transition

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FYPO:0000608 - abnormal cell cycle arrest in mitotic M phase

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FYPO:0006101 - abnormal interphase microtubules

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FYPO:0003738 - abnormal mitotic cell cycle arrest with condensed chromosomes

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FYPO:0000444 - abnormal mitotic cell cycle arrest with replicated DNA

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FYPO:0004596 - abnormal negative regulation of DNA replication initiation during mitotic G2 phase resulting in complete rereplication

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FYPO:0003378 - abolished meiosis I

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FYPO:0003379 - abolished meiosis II

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FYPO:0000941 - abolished protein localization to mitotic spindle pole body

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0001122 - elongated vegetative cell

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FYPO:0002700 - increased protein kinase activity

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FYPO:0000836 - increased protein level

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FYPO:0000650 - increased septation index

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FYPO:0000252 - increased spontaneous diploidization

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FYPO:0003529 - inviable after spore germination, multiple cell divisions, cell cycle arrest in mitotic interphase, elongated cells

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FYPO:0003128 - inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic M phase

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0004382 - meroterically attached lagging mitotic chromosomes

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FYPO:0001928 - normal regulation of mitotic cell cycle

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0003481 - viable elongated vegetative cell, elongated upon mitotic entry

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