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Haploid genotype - cdc17-K42(E298K aa)

Genotype summary

Description
cdc17-K42(E298K aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc17 (SPAC20G8.01)ATP-dependent DNA replication ligase Cdc17cdc17-K42E298Kamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000608 - abnormal cell cycle arrest in mitotic M phase

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FYPO:0000051 - abnormal meiosis

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FYPO:0000444 - abnormal mitotic cell cycle arrest with replicated DNA

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FYPO:0000348 - abnormal spore morphology

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FYPO:0000913 - abnormal sporulation resulting in formation of ascus containing non-uniform spores

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FYPO:0000664 - abolished catalytic activity

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FYPO:0002678 - abolished protein phosphorylation

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FYPO:0000663 - decreased catalytic activity

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FYPO:0000584 - decreased sporulation frequency

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0005773 - elongated mononucleate aseptate vegetative cell

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FYPO:0002019 - elongated telomeres during vegetative growth

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FYPO:0006689 - increased insertion/deletion frequency

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FYPO:0001815 - increased level of Okazaki fragments

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FYPO:0000455 - increased number of double-strand break sites during vegetative growth

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0001038 - increased protein phosphorylation during vegetative growth

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FYPO:0002082 - increased protein ubiquitination during vegetative growth

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0001490 - inviable elongated vegetative cell

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0000256 - mutator

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FYPO:0001133 - normal DNA replication

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FYPO:0000838 - normal protein localization to nucleus during vegetative growth

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FYPO:0000776 - normal protein phosphorylation during vegetative growth

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FYPO:0004423 - normal protein threonine phosphorylation

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FYPO:0000097 - sensitive to caffeine during vegetative growth

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FYPO:0001719 - sensitive to lithium

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FYPO:0002060 - viable vegetative cell population

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