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Haploid genotype - cdc18+(wild type)[Knockdown]

Genotype summary

Description
cdc18+(wild type)[Knockdown]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc18 (SPBC14C8.07c)MCM loadercdc18+wild typewild_typeKnockdown

Annotation

Single locus phenotype

FYPO:0001430 - abnormal mitotic cell cycle arrest with unreplicated DNA

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FYPO:0004359 - abolished mitotic cell cycle DNA replication checkpoint

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FYPO:0001508 - abolished protein localization to chromatin during vegetative growth

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FYPO:0002577 - decreased chromatin binding

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FYPO:0002909 - decreased protein localization to chromatin during vegetative growth

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FYPO:0002679 - decreased protein phosphorylation

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FYPO:0001838 - decreased protein phosphorylation during vegetative growth

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FYPO:0001974 - increased number of cells with 1C DNA content

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FYPO:0001490 - inviable elongated vegetative cell

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FYPO:0003075 - normal protein kinase activity

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FYPO:0004083 - normal protein level

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FYPO:0000838 - normal protein localization to nucleus during vegetative growth

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FYPO:0005107 - normal regulation of mitotic DNA replication initiation

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